Dr. Geoffrey Sher

Measuring and interpreting Blood hCG to Assess Pregnancy Viability Following ART Treatments

I know of no medical announcement associated with the degree of
emotional anticipation and anguish as that associated with a pending
diagnosis/confirmation of pregnancy following infertility treatment.
In fact, hardly a day goes by where I am not confronted by a patient
anxiously seeking interpretation of a pregnancy test result.

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Infertility Caused by Pelvic Tuberculosis: An Easily Missed Diagnosis

Tuberculosis is caused by a bacterium known as mycobacterium
tuberculosis. It is primarily an infectious process that involves the
lungs it is capable of spreading elsewhere (extra-pulmonary TB) It can
spread to the woman’s reproductive tract and cause infertility. The
commonest site is the Fallopian tubes. From there it can spread to
uterine lining (endometrium) and to the ovaries. The lower genital
tract (cervix, vagina and vulva can also be affected b…

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Autism and Reproduction

Autism Spectrum Disorder (ASD) encompasses a range of conditions that
most commonly affect males and are characterized by lifelong
neurodevelopmental derangements manifesting as deficiencies in social
interaction, verbal and nonverbal communication, and dysfunctional
interests and behavioral pattern that range from social isolation,
delayed speech, and repetitious movement, to Asperger’s syndrome,
characterized by higher levels of cognition and social behavior. It
result from a comple…

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IVF Failure and Implantation Dysfunction: The Role of Endometrial Thickness, Uterine Pasthology and Immunologic Factors

The considerable emotional, physical and financial burden associated
with infertility treatment in general and with IVF in specific, demand
that factors known to affect outcome be identified and regulated prior
to initiating treatment. Just as a successful garden needs a
”good” seed properly planted in fertile soil to produce healthy
plants, successful embryo implantation requires a good seed
(genetically “norma…

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Ovarian Stimulation For Women with Diminished Ovarian Reserve (DOR) and in Older Women undergoing IVF

Two main factors determine the quality of a woman’s eggs at
ovulation or egg retrieval.  First is her age and second is the
protocol used for ovarian stimulation. With the possible the exception
of cases where there is severe sperm dysfunction, it is the
chromosomal integrity of the egg rather than t…

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Fertility Drugs for IVF: How safe are They and do They Cause Cancer?

Are unsuspecting infertile women at increased risk through the drugs
and treatment they administered with fertility treatment? When it
comes to fertility drugs (e.g. gonadotropins such as Follistim, Gonal
F, Puregon, Bravelle, Menopur, Lupron, Superfact, Ganirelix, Cetrotide
etc.,) used in IVF, claims that there are long term serious side
effects have been grossly over stated. While it is indeed a fact
indiscriminate overdosing of women who is inor…

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IVF following previous Tubal ligation is a Better Option than Surgical Reversal

There is a relatively high success rates following tubal re-connection
(reanastomosisis) in cases of previous tubal ligation (a birth rate of
+/- 50% within 3 years of a successful surgery). However, IVF
performed in a center of excellence produces almost the same success
rate following a single attempt and is far less invasive than surgery.
IVF also does not require general anesthesia, hospitalization, or a
protracted time off work. Moreover by doing IVF …

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COMMERCIAL EGG BANKING FOR FERTILITY PRESERVATION (FP) AND A REPOSITORY FOR DONOR EGGS

For more than a thirty years, attempts by medical scientists to freeze
and bank (cryobank) a woman’s eggs have yielded limited success. In
fact, to date, since the birth of the 1st “frozen egg baby” in the
mid 1980’s, fewer than 2,000 births resulting from the fertilization
of thawed eggs have been reported worldwide. Compare this to > 4
million IVF babies born worldwide in the same time period, and
approximately 1,000,000 babies resulting from the…

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The Role of Gender Selection: The Pros and Cons

Couples have for centuries sought to influence the gender of their
offspring. More than seven centuries ago the ancient Chinese developed
a birth calendar said to be able to predict gender on the basis of
when conception occurred. Later, the ancient Greeks suggested that by
lying on her right side during intercourse, a woman could improve the
likelihood of having a male child. And 300 years ago, the French
suggested that placing a ligature around the right…

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The BCP: Does Launching a Cycle of Controlled Ovarian Stimulation (COS) Coming off the BCP Compromise Response?

One often hears the expressed opinion that the BCP suppresses response
to ovarian stimulation. This is not the case, provided that the BCP is
overlapped with administration of an agonist (e.g. Lupron, Buserelin,
Superfact) for several days leading up to the start of menstruation
and the initiation of ovarian stimulation cycle with gonadotropin
drugs. If the latter precaution is not taken, and the cycle of
stimulation is initiated coming directly off the BC…

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