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Infertility diagnosis/treatment

The causes of infertility are multiple and are often difficult to define but may include anatomical conditions involving tubal patency and/or function as well as diseases of the testicles and/or or sperm ducts, dysfunctional levels of certain hormones in both men and women, and ovulation difficulties in women.

Recurrent miscarriage diagnosis/treatment

The time has come to embrace the reality that the term “unexplained” is rarely applicable to 1) infertility of unknown cause, 2) repeated IVF failure, and 3) recurrent pregnancy loss (RPL). More often than not, rather than being “unexplained,” the condition is simply ignored and as such remains “undiagnosed.” All that is needed is to investigate and treat the issue appropriately in order to solve the problem.

Egg freezing for future fertility

There are many reasons why patients may need to preserve their fertility. For some, it may be a focus on education and career delays and for others it may be due to an illness. Although the decline in reproductive potential that occurs with age cannot be reversed, freezing your eggs at a younger age may allow the eggs to be preserved until you are ready to conceive. While there are no guarantees, using cryopreserved eggs may improve your chances for pregnancy in the future.

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Ask Our Doctors

Dear Patients,
I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

I Have a Question

Positive lads after 4th lit treatment

Name: Irit L

Dear Dr. Sher,

Thank you for your answer.
I did take ivig before pregnancy was diagnosed. Took 30g ivig on ovulation and on positive hgc test but it faild to relax my immune system.

I refuse to take steroids as i was provided with 20mg prednison for 8 months. I had adison crises and ovarian shutdown with extremly elevated fsh. Took me a year to heal my ovaries and get pregnant again after i did a big research how to heal my ovaries and it luckily worked.

I want to try treatments that wont affect egg quality at all like ivig, lit, intralipids and plasmapheresis. I hope that i’ll manage to bank embryos for surrogacy but i am 44 so i need to see if ivf works for me.

I have a few questions:
1. I Did 3 lit treatments 1.5 years ago. Lads were negative.
After the last pregnancy loss I did the 4th lit. Finally lad became weak positive 40%. Do you think that positive lads gives me a better chance to carry a pregnancy?

2. Do you think tacro can be a good option after failing with ivig? Does it have horrible side effects like steroids?

Thanks a lot for your advises and terrific website. It helped me a lot.
Irit

This is my original message:
Just had my 6th miscarriage, natural conception with ivig and lit.

I am disgnosed with partial dq-alpha gene match (0301) and elevated nk cells.
We have a 4.5 years old son concieved naturaly and easily.

My miscarriages are very early.
We had 3 LITs a year and a half ago however LAD is still negative.
I took 30g IVIG on ovulution and on positive hgc test.
Aldo added ovidral on positive hgc test.

Immune pannel taken a day after the second ivig showed elevated tnf-alpha, elevated nk cell activity and 29.4% nk cell count.

We lost the pregnancy, the sac was empty and matched 4 weeks size.

Answer:

I Did 3 lit treatments 1.5 years ago. Lads were negative.
After the last pregnancy loss I did the 4th lit. Finally lad became weak positive 40%. Do you think that positive lads gives me a better chance to carry a pregnancy?

A: I do not believe this to be so

2. Do you think tacro can be a good option after failing with ivig? Does it have horrible side effects like steroids?

A: Sorry, I have no experience with this treatment.

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Causes of Infertility

Causes of Infertility

Infertility refers to the inability to conceive despite engaging in well-timed unprotected sex for...

Our Team

The emphasis we put on innovative, state-of-the-art technology began with our founder, Dr. Geoffrey Sher, one of the pioneers in the field of IVF, who has been influential in the births of more than 17,000 IVF babies. Dr. Sher plays an active role alongside our medical director, Dr. Drew Tortoriello. Together they have over 55 years of clinical and academic experience in the field of Reproductive Medicine.

Together, they were the first to introduce Preimplantation Genetic Testing which vastly increases the chances of IVF success and is now performed worldwide. They also pioneered the testing and treatment of Immunologic Implantation Dysfunction (IID) that frequently leads to “unexplained” infertility, repeated IVF failure, and recurrent miscarriage. We’re able to conduct a variety of other treatments and tests right on site. For example, we offer on-site sperm testing to ensure proper sperm selection techniques are used to create the healthiest possible embryos.

For those women seeking to preserve their fertility, we offer vitrification, a state-of-the-art technology that ensures their eggs will ultimately be thawed successfully.

From the moment you walk into our state-of-the-art New York fertility clinic, you’ll feel the warmth and compassion that will define your experience with us. Drew Tortoriello, MD serves as our Medical Director. He’s an outstanding fertility specialist that you’ll find to be caring, compassionate and personable.

When you receive fertility treatment with us, your doctor will participate with hands-on management of your case throughout your treatment. We’ve gained a reputation of being the place to turn to when all other treatment options have failed, and patients are searching for hope and fresh alternatives.

TL;DR:

  • Our doctors are among the best in the world, with over 55 years of combined experience
  • Together, they pioneered several tests and treatments that can help where other treatments have failed
  • We do many tests right here at the clinic, which means faster results and ensures proper techniques are used
  • Your doctor will be with you at every step of your treatment
  • Everyone here will get to know you during your treatment so you won’t just feel like a number
  • We’re known for being the clinic to go to when all other treatments have failed
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