Dr. Geoffrey Sher, Author at Sher Fertility Solutions | Begin Your Fertility Journey

Diagnosing and Treating Immunologic Implantation Dysfunction (IID)

Central to making a diagnosis of an immunologic implantation
dysfunction (IID) is a need for the appropriate interpretation of
Natural Killer Cell Activity (NKa). In this regard, one of the
commonest and most serious errors, is interpret the blood
concentration of natural killer cells as being relevant. Rather it is
the activity (toxicity) of NK cells that matters as mentioned. This
activity can best be measured using the blood, K-562 target cell test
(the gold standard). and/ o…

Diagnosing and Treating Immunologic Implantation Dysfunction (IID) Read More »

Raised Blood Prolactin Levels (Hyperprolactinemia) in Women Undergoing Infertility Treatment

Dr. Geoffrey Sher

Prolactin (PRL) is a protein hormone (closely related to human growth
hormone
[https://blog.drgeoffreysherivf.com/human-growth-hormone-administration-in-ivf-does-it-enhance-eggembryo-quality-and-outcome/])
that is secreted by specialized cells in the anterior part of the
pituitary gland. In addition, the hormone is also produced and
secreted by a broad range of other cells in the body, most prominently
various immune cells, the brain, and the endometrium (lining of t…

Raised Blood Prolactin Levels (Hyperprolactinemia) in Women Undergoing Infertility Treatment Read More »

What Is Diminished Ovarian Reserve?

Dr. Geoffrey Sher

Ovarian reserve refers to the reproductive potential left within a
woman’s two ovaries based on number of eggs (oocytes). If you have
diminished ovarian reserve, this means that the number of your eggs is
lower than expected for your age. Although the relative quality
(chromosomal normalcy or competency) of eggs in DOR patients may also
be compromised, we often see quality being more aligned with a
patient’s age rather than her number of eggs.
Normal aging causes mos…

What Is Diminished Ovarian Reserve? Read More »

Violet™ Artificial Intelligence (AI)-based Software: A Break-through in the Field of Egg Banking which Reliably Predicts Reproductive Potential by Scoring “Egg Competency”

Dr. Geoffrey Sher

In order for a human embryo to develop into a viable, healthy
pregnancy it needs to be “competent” (capable, upon being
transferred to the uterus, of propagating a viable pregnancy).
Currently, the most reliable determinant of such embryo
“competence” is the measurement of the number of chromosomes in
the embryo’s cells (i.e., its karyotype). An embryo whose cells have
all 46 chromosomes intact, is seen as a requirement and therefore
deemed to be one that is most likel…

Violet™ Artificial Intelligence (AI)-based Software: A Break-through in the Field of Egg Banking which Reliably Predicts Reproductive Potential by Scoring “Egg Competency” Read More »

Total Absence of Sperm in the Ejaculate due to Complete Obstruction of the Vas deferens: Congenital or acquired.

Dr. Geoffrey Sher

Following male orgasm, sperm are ejaculated after traveling rapidly in
sequence through the vas deferens duct, the prostate gland, and the
urethra. The vas deferens must be patent to allow the passage of sperm
in the ejaculate.

CAUSES OF TOTAL OBSTRUCTION OF THE VAS DEFERENS:

* _Primary occlusion: Congenital (Bilateral) Absence of the Vas
Deferens (CBAVD): _In some cases men are born with occlusion of
the vas deferens, obstructing the…

Total Absence of Sperm in the Ejaculate due to Complete Obstruction of the Vas deferens: Congenital or acquired. Read More »

Egg Banking-Fertility Preservation

Dr. Geoffrey Sher

THE BOTTOM LINE IS THAT BECAUSE OF THE TRAUMATIC EFFECT OF FREEZING ON
EGG VIABILITY AND “COMPETENCY” THE STATISTICAL CHANCE OF EACH
FROZEN/ THAWED EGG ULTIMATELY RESULTING IN A BABY IS ONLY AT BEST
6-8%. SO, WHILE SUCCESS RATES FOLLOWING THE TRANSFER OF EMBRYOS
DERIVED FROM FROZEN EGGS HAVE INDEED IMPROVED SUBSTANTIALLY OVER THE
LAST 5-10 YEARS, THEY REMAIN SIGNIFICANTLY LOWER THAN WHEN EMBRYOS
DERIVED THROUGH FERTILIZATION OF FRESH (NOT FROZEN) EGGS, ARE
TRANSFERRED. …

Egg Banking-Fertility Preservation Read More »

Recurrent Pregnancy Loss (RPL)

Dr. Geoffrey Sher

The bottom line is that because of the traumatic effect of freezing on
egg viability and “competency” the statistical chance of each
frozen/ thawed egg ultimately resulting in a baby is only at best
6-8%. So, while success rates following the transfer of embryos
derived from frozen eggs have indeed improved substantially over the
last 5-10 years, they remain significantly lower than when embryos
derived through fertilization of fresh (not frozen) eggs, are
transferre…

Recurrent Pregnancy Loss (RPL) Read More »

Prolactin (PRL)

Dr. Geoffrey Sher

Prolactin (PRL) is a protein hormone (closely related to human growth
hormone
[/blog/human-growth-hormone-administration-in-ivf-does-it-enhance-eggembryo-quality-and-outcome/])
that is secreted by specialized cells in the anterior part of the
pituitary gland. In addition, the hormone is also produced and
secreted by a broad range of other cells in the body, most prominently
variou…

Prolactin (PRL) Read More »

EZ-IVF

Dr. Geoffrey Sher

…

EZ-IVF Read More »

EZ-IVF: AN IMPROVED , LOW-COST, LOW-STIMULATION, SAFE & SUCCESSFUL ALTERNATIVE T0 MINI-IVF AND NATURAL CYCLE-IVF

Dr. Geoffrey Sher

Geoffrey Sher MD & Drew Tortoriello MD
Mini-IVF is a procedure that involves ovarian stimulation with oral
fertility drugs such as clomiphene or letrozole to promote the
development of follicles, for egg extraction. This is on the pretext
that Mini-IVF, involves the administration of oral low-dosage
medication, cuts down on cost, reduces the need for intensive
monitoring and is highly successful. Natural-cycle (NC)- IVF is an
extension of the same concept….

EZ-IVF: AN IMPROVED , LOW-COST, LOW-STIMULATION, SAFE & SUCCESSFUL ALTERNATIVE T0 MINI-IVF AND NATURAL CYCLE-IVF Read More »

(646)792-7476

(702)533-2691

Dr. Geoffrey Sher

Diagnosing and Treating Immunologic Implantation Dysfunction (IID)

Raised Blood Prolactin Levels (Hyperprolactinemia) in Women Undergoing Infertility Treatment

What Is Diminished Ovarian Reserve?

Violet™ Artificial Intelligence (AI)-based Software: A Break-through in the Field of Egg Banking which Reliably Predicts Reproductive Potential by Scoring “Egg Competency”

Total Absence of Sperm in the Ejaculate due to Complete Obstruction of the Vas deferens: Congenital or acquired.

Egg Banking-Fertility Preservation

Recurrent Pregnancy Loss (RPL)

Prolactin (PRL)

EZ-IVF

EZ-IVF: AN IMPROVED , LOW-COST, LOW-STIMULATION, SAFE & SUCCESSFUL ALTERNATIVE T0 MINI-IVF AND NATURAL CYCLE-IVF

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Dr. Geoffrey Sher

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