Polycystic ovary syndrome (PCOS) is a common hormonal system disorder
among women affecting between 5% and 10% of women of reproductive age
worldwide. Women with PCOS may have enlarged ovaries that contain
small collections of fluid — called follicles — located in each
ovary as seen during an ultrasound. The condition is characterized by
abn…
IVF FAILURE AND RECURRENT PREGNANCY LOSS WITH GUEST DR. GEOFFREY SHER
Dr. Geoffrey Sher is an internationally renowned expert in the field
of ART. He trained under the fathers of IVF, Dr. Patrick Steptoe and
Robert Edwards in the UK. He came to the United States in 1982 to
establish the first private non-university-based IVF program, the
fourth IVF clinic in the nation. He then expanded his presence to
include 10 IVF cente…
IVF Failure and Recurrent Pregnancy Loss with guest Dr. Geoffrey Sher Read More »
EGG FREEZING VERSUS BANKING OF PGS-TESTED BLASTOCYSTS, IN A YOUNG
WOMAN WITH PREMATURELY DIMINISHING OVARIAN RESERVE (DOR)?
Questions posed:
Hi Dr Sher, thank you for all that you do in sharing your fertility
knowledge. I have learned a lot from your articles and
questions/comments. I was also hoping to get your advice:
I am 32 almost 33 and my fiancé is 27. We just got engaged and are
ready to start building our family. I was thinking about freezi…
Prolactin (PRL) is a protein hormone (closely related to human growth
hormone
[https://drgeoffreysherivf.com/human-growth-hormone-administration-in-ivf-does-it-enhance-eggembryo-quality-and-outcome/])
that is secreted by specialized cells in the anterior part of the
pituitary gland. In addition, the hormone is also produced and
secreted by a broad range of other cells in the body, most prominently
various immune cells, the brain, and the endometrium (lining of the
uterus). …
Raised Blood Prolactin Read More »
Acupuncture involves the insertion of thin needles into the skin along
so called meridians (energy channels). It has been used in China for
centuries to regulate and treat many health disorders including
ailments involving the female reproductive system.
When I visited China back in 1987, I actually witnessed a Cesarean
birth being performed without sedation, pain killers or anesthesia…
using only acupuncture. The mother lay there relaxed, conversing with
the surgeon and…
Acupuncture and IVF: Does it Improve Success? Read More »
When women with infertility due to endometriosis seek treatment, they
are often advised to first try ovarian stimulation (ovulation
Induction) with intrauterine insemination (IUI). As with essentially
all reasons for infertility, IVF offers a much higher chance of
success than proceeding with multiple IUI cycles in endometriosis
patients. This is not to suggest that all women with
infertility-related endometriosis should automatically resort to IVF.
Quite to the contrary; in spi…
Endometriosis and IVF Read More »
Whenever a patient fails to achieve a viable pregnancy following
embryo transfer (ET), the first question asked is “Why?”
Was it simply due to bad luck? How likely is the failure to recur in
future attempts and what can be done differently to avoid it happening
next time?.
It is an indisputable fact that any IVF procedure is at least as
likely to fail as it is to succeed. Thus when it comes to outcome,
luck is an undeniable factor. Notwithstanding, it is incumben…
Embryo transfer (ET) is undoubtedly a rate limiting factor in IVF. The
IVF doctor’s expertise in performing ET is one of the most important
factors determining IVF outcome. It requires the dexterity, skill, and
gentle touch that can only truly come through experience. Of all the
procedures in IVF, this is the most difficult to teach. It is a true
“art” and there is little doubt that many women will fail to
conceive following IVF from a suboptima…
Embryo Transfer: Simply Crucial in IVF Read More »
In 1989, Dr. Sher first published a study that examined the
correlation between the thickness of a woman’s uterine lining (the
endometrium), and the odds of embryo implantation in IVF patients.
This study revealed that when the uterine lining measured at least 9mm
in thickness by the day of the “hCG trigger” (in fresh IVF
cycles), or at the time of initiating progesterone therapy (in embryo
recipient cycles, e.g. frozen embryo transfers-FET, egg donation-IVF
etc.) , pregna…
A Thin Uterine Lining: Vaginal Viagra may help Read More »
Central to making a diagnosis of an immunologic implantation
dysfunction (IID) is a need for the appropriate interpretation of
Natural Killer Cell Activity (NKa). In this regard, one of the
commonest and most serious errors, is interpret the blood
concentration of natural killer cells as being relevant. Rather it is
the activity (toxicity) of NK cells that matters as mentioned. This
activity can best be measured using the blood, K-562 target cell test
(the gold standard). and/ o…
Diagnosing and Treating Immunologic Implantation Dysfunction (IID) Read More »
