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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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216 answers

Uterine & Endometrial Health

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Infertility Basics Aug 7, 2023

Fertility options

My wife was diagnoses last year with Adenomyosis after having a miscarriage, and had a DNC. We've been having trouble getting pregnant ever since, and would like to know all options. We saw this on a show, and wondering if… — Adam L.

Dr. Geoffrey Sher answered

Adenomyosis is a condition where endometrial glands develop outside the uterine lining (endometrium), within the muscular wall of the uterus (myometrium). Definitive diagnosis of adenomyosis is difficult to make. The condition should be suspected when a premenopausal woman (usually>25 years of age) presents with pelvic pain, heavy painful…
Ovarian Stimulation & OHSS Aug 5, 2023

IVF FET PREP

I am doing my first FET prep cycle - I am on oral estrogen (2mg) and estrogen patches (0.1mg/day) I started at 2 patches and 1 pill per day and then gradually bumped up to 3 pills and 3 patches… — Mikie D.

Dr. Geoffrey Sher answered

There are different approaches to hormonal preparation of the uterine lining for FET. In my practice, the following is the approach I take.. I think using this might prevent the kind of response you experienced last time. Until less than 3 decades ago, most women undergoing IVF would…
Embryos & Genetic Testing Aug 5, 2023

Repeated Implantation/Loss

Hi There, I had 12 'healthy' embryos from 2 retrevials . NO natural cycles all with. Progesterone, Esradiol, Prednisone, Baby Aspirin Did 3 transfers for these . 1st failed. - did ERA came back normal. 2nd. B.O. - needed two… — Katrina S.

Dr. Geoffrey Sher answered

Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. In the pursuit of optimizing outcome with IVF, the clinician has a profound responsibility to meticulously assess and address this important issue if IVF success is to be optimized. This is especially relevant in cases…
Embryos & Genetic Testing Aug 5, 2023

Do You Offer Reproductive Immunology As A Separate Specialty/Service?

Hello Dr. Sher, I am a patient working with an IVF Clinic that holds 2 more of my PGT-A Euploid Embryos (using Donor Eggs and my husband's sperm), but we have unfortunately arrived at a crossroads where my smaller clinic… — Deanna T.

Dr. Geoffrey Sher answered

Of course we offer the service independent of whether the patient undergoes egg retrieval with us. Geoff Sher In the world of assisted reproduction, when IVF fails repeatedly or without explanation, it's often assumed that poor embryo quality is the main culprit. However, this view oversimplifies the situation.…
Uterine & Endometrial Health Aug 1, 2023

Ethanol Sclerotherapy?

Hi, I have what appears to be a 7cm endometrioma on my left ovary. I had surgery to remove an ovarian cyst on the same ovary a year ago and it regrew to the same size within 4 months. An… — Sarah K.

Dr. Geoffrey Sher answered

I introduced ovarian sclerotherapy using 5% tetracycline hydrochloride (THCL). Unfortunately we cannot access THCL any longer. Therefore, surgery is advised in your case. Personally, it is rarely necessary to remove the entire ovary. In my opinion, the cyst should be isolated and removed leaving most of the ovary…
Uterine & Endometrial Health Aug 1, 2023

High progesterone

Hi Dr., On the day of my last fresh transfer my progesterone level was 350nmol/l (far too high) & I still wonder if it contributed to my failed cycle. Five days later I produced/was leaking breast milk & had symptoms… — Rosie S.

Dr. Geoffrey Sher answered

Respectfully, I do not believe your sad loss had anything to do with the high progesterone. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization…
Embryos & Genetic Testing Jul 26, 2023

Receptiva Test

Hi Dr. Sher, I have a question. I am 30 years old. No known medical issues, with unexplained infertility. I did a recent retrieval, and got 5 chromosomally normal embryos. I have transferred 2 now, both failed. The first was… — Rosina H.

Dr. Geoffrey Sher answered

Understanding the Power of Receptiva Test The Receptiva Test is often inconclusive but would do no harm. However, 30% of endometriosis is associated with an immunologic implantation dysfunction (IID). If present and there is evidence of increased natural killer cell activity (NKa) and/or antiphospholipid antibodies, this could cause…
Embryos & Genetic Testing Jul 26, 2023

Endometriosis

Hello Dr Im 35yo. Been trying to conceive since 2020. Did 3 IUI in 2022-did not work. Normal hormone levels. Miraculously got pregnant for the first time in Jan 2023 but miscarriage at around 7 weeks reports say likely due… — Pareet A.

Dr. Geoffrey Sher answered

You are correct, the Receptiva test is often inconclusive, but would do no harm. And, unless ultrasound shows endometriotic cysts I would not do a laparoscopy or take Lupron. Rather, I would undergo blood testing for an immunologic implantation dysfunction (IID) specifically looking for antiphospholipid antibodies (APA) and…
Egg Health & Ovarian Reserve Jul 22, 2023

Cut off Age for using own egg

Do you have a cut off age for using own egg. I am 46 and have never been pregnant, my last amh was about 0.4. Main reason of my infertility is currently blocked tubes which i experienced after fibroid surgery… — Jane M.

Dr. Geoffrey Sher answered

Our cut off for egg retrievals is 47Y. Frozen embryo transfers....no definitive cut off. See below: Age should never be a barrier to hope and fulfillment when it comes to IVF. Many women in their early to mid-40s are successfully having IVF babies using their own eggs, especially…
Uterine & Endometrial Health Jul 22, 2023

Viagra

I inserted viagra and the next day it came out what does that mean ? It was recommended by the doc for blood flow in my uterus, did I do it wrong or why did it take the next day… — Aisha A.

Dr. Geoffrey Sher answered

The dosage is 25mg inserted high in the vagina 4 times daily from early in the cycle to the day of hCG or progesterone administration. Back in 1989, I conducted a study that examined how the thickness of a woman's uterine lining, known as the endometrium, affected the…
Uterine & Endometrial Health Jul 22, 2023

PRP treatment request

Dear Dr. Tortoriello, I have extremely low ovarian reserve despite my age of 32. I had done PRP before in Korea, and I saw 3 follicles 2 months after, which is rare for me (I usually see one). Although I… — Jiseon P.

Dr. Geoffrey Sher answered

Yes we do! However, to be honest, I am not a true believer. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions…
Embryos & Genetic Testing Jul 22, 2023

Implantation dysfunction

I saw your interview on THE EGG WISPERER podcast and really appreciated your information and inspiration. We have been trying to conceive for about 6 years now (age 37) with no children, have low AMH (last tested about 18 months… — Ponda C.

Dr. Geoffrey Sher answered

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Uterine & Endometrial Health Jul 19, 2023

Took Progesterone tablet during IVF

Hi, I am doing cycle 3 of IVF stimulation. Day 6 today and I took progesterone tablet 10 mg by mistake. I am worried now if it will affect my IVF cycle. Please advise. Thanks. — Renu V.

Dr. Geoffrey Sher answered

That is not sufficient to disrupt your cycle...in my opinion. Discuss with your treating RE. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher…
Uterine & Endometrial Health Jul 17, 2023

Endometrial lining

I am doing a frozen embryo transfer I am taking 6 x2mg Estradiol tablets a day. Endometrial lining on day 14 was 8.1mm then on day 16 was about 7 mm. I am now taking progesterone and in 5 days… — Reema K.

Dr. Geoffrey Sher answered

I would not go ahead with a lining of
Uterine & Endometrial Health Jul 17, 2023

Vagina Sildenafil

Hi there We are in the UK but cannot get vaginal Sildenafil. Do you ship to the UK at all with a prescription? Thanks — Sean B.

Dr. Geoffrey Sher answered

Sorry! We do not produce compounded Viagra suppositories. We obtain it from MDRx located in Encino, CA. THE IMPACT OF A THIN UTERINE LINING ON EMBRYO IMPLANTATION: THE BENEFITS OF VIAGRA THERAPY Geoffrey Sher MD Back in 1989, I conducted a study that examined how the thickness of…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

216 answers

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