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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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160 answers

Egg Health & Ovarian Reserve

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Clinic & Practice Sep 28, 2026

Consultation Request – DOR and Difficult Response to IVF Stimulation

Dear Dr. Sher, I would like to arrange a consultation regarding my IVF history and response to stimulation. I have diminished ovarian reserve (DOR) with a very low AFC and have had several disappointing cycles with inconsistent responses. My current… — Daniela K.

Dr. Geoffrey Sher answered

It would be my pleasure to interact with you. However, you should please contact my office Manager, Patti Converse and have her send you a brief questionnaire to complete, upon which she will set you up with an online consultation and we can discuss your issues in detail..…
Egg Health & Ovarian Reserve Sep 21, 2026

Cyst

Do you have recommended someone with an chocolate cyst to get sclerotherapy treatment ? Planning on freezing eggs and have no symptoms of endometriosis and OBGYN said they didn’t think I should do Surgery yet as it lowers egg quality… — Jen L.

Dr. Geoffrey Sher answered

Here is an article I wrote on sclerotherapy, a procedure I pioneered >15 years ago. We should tal. Please email Patti , my asistant at cocierge@sherivf.com and she can arrange for us to have an online consultation to discuss. Addressing Ovarian Endometriotic Cysts, and Fertility A Simpler, Safer…
Egg Health & Ovarian Reserve Jul 6, 2026

Hashimotos DOR- Protocol

Hello Dr, I’m 37 years old and have Hashimotos and Diminished ovarian reserve what t protocol would you recommend for me — Emoata O.

Dr. Geoffrey Sher answered

Here is some informaion on the effect of Hashimoto's on embryo implantation. Unfortunately I would need a lot more information to recommend a protocol for you. I suggest you contact Patti at concierge@sherIVF.com and set up an online consultation to talk it through with me. Geoff Sher Thyroid…
Egg Health & Ovarian Reserve Jan 21, 2026

Research papers on trigger dosage for POI/DOR patients

Dear Dr. Sher, with great interest have I read your articles on the "empty" follicle syndrome: I was diagnosed with premature ovarian insufficiency incl. elevated LH levels. In my two egg retrieval attempts only 1 egg could be retrieved out… — Lena T.

Dr. Geoffrey Sher answered

I suggest you email Patti Converse (concierge@sherivf.com and set up an online consultation with me. Geoff Sher
Egg Health & Ovarian Reserve May 29, 2025

Stimulation protocols for DOR in 45 yr old

I'm trying to write up the protocol outlined in one of your recent videos with the egg whisper to take to my Dr. whom is going to do my next cycle. We've started the HGH and we did the PRP… — Ariane B.

Dr. Geoffrey Sher answered

I would never presume tom tell your doctor what to do with regard to your stimulation. I can tell you that regardless of protocol, the chance of propagating euploid ("competent") eggs at 45y is very slim (!:2o eggs or so will end up being viable). Obviously if in…
Egg Health & Ovarian Reserve Apr 27, 2025

Lack of maturation of eggs in stimulation cycle

Dear Dr. Sher, I just watched your video on egg maturation and learned more than I have in over a year of reading and asking questions on this. My question also relates to egg maturation but specifically on why eggs… — Laura C.

Dr. Geoffrey Sher answered

When confronted with such an exaggerated response, doctors often trigger egg maturation by cutting the cycle short through triggering early. While this protects against OHSS, the eggs are oft yet not ready for maturation. This leads mto "poor egg yield and quality . Second, in such cases doctors…
Egg Health & Ovarian Reserve Apr 27, 2025

Empty folicals

Hi, I'm on my first round of ivf due to same sex relationship. Im from the UK. I have just had my first egg retrieval and I'm bitterly disappointed with the amount of egg they collected. I'm 37, amh 14.1,… — Katie M.

Dr. Geoffrey Sher answered

Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely to happen when multiple attempts are needed to retrieve an egg from a follicle, indicating the egg may have chromosomal abnormalities. The…
Egg Health & Ovarian Reserve Mar 13, 2025

Failed Embyro transfer

Hi, I have low AMH. I have had 1 round of IVF and did not obtain any embyros. I had a second round of ICSI and obtained 3 embyros. From this round, I have had two Embyro transfers which did… — Tara B.

Dr. Geoffrey Sher answered

It is very likely that your issue is an embryo quality issue stemming from the egg. The egg rather than the sperm is the main determinant of embryo "competency". Women with diminished ovarian reserve are at at greater risk of poor egg quality if the protocol used for…
Egg Health & Ovarian Reserve Jan 29, 2025

Cyst at baseline for FET

Hi Dr. Sher, a resolving functional hemorrhagic cyst was found during ultrasound for my modified natural (Letrazole assisted) FET. I had delayed ovulation and they performed an ultrasound and found the cyst. On Friday, ultrasound showed cyst was 36 mm,… — Peg T.

Dr. Geoffrey Sher answered

Very respectfully, I would not enter an FET until the cyst is gone and you have had at least one interim natural cycle. I would also strongly recommend a medicated FET. FROZEN EMBRYO TRANSFER : ONE PREFERRED APPROACH AT SFS. Two decades ago, when women went through IVF…
Egg Health & Ovarian Reserve Jan 23, 2025

Fertility at 41

Hello Dr Sher, I am a physician G3P2 who has gone through 6 cycles of IVF for my 3rd child. (My elder two are 11 and 9 who were naturally conceived and delivered NSVD). I have done luteal phase stimulation… — Heena P.

Dr. Geoffrey Sher answered

Thank you for reaching out to me. We should talk. I recommend that you contact my assistant, Patti Converse at concierge@sherivf.com and set up an online consultation with me to discuss. In the meanwhile, please see below. Geoff Sher ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN…
Egg Health & Ovarian Reserve Jan 11, 2025

Dor Diagnosis

I’ve been diagnosed with Dor. First antagonist cycle only ended up with 4 follicles on trigger day after 10days of stimming. However, e2 never got above 380 and seemed to have dipped on trigger day to 373. Clinic still proceeded… — Avie H.

Dr. Geoffrey Sher answered

There is a great deal to discuss! I suggest that you contact my assistant, Patti (concierge@sherIVF.com ) and set up a time to discuss online. ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF Understanding the impact of age and ovarian reserve on the success of in…
Egg Health & Ovarian Reserve Nov 24, 2024

IVF

I am 28 and my husband is 27. My husband was diagnosed with male factor infertility 1 year ago (low count, low motility). Our first IVF round produced 17 eggs, 14 mature, 14 fertilized and 6 untested fair quality blasts.… — Payton D.

Dr. Geoffrey Sher answered

I do not think the reason for your failed cycles was due to the male factor. It sounds more like an implantation dysfunction. We should connect online and discuss this in depth. I think I can help. Please call my assistant, Patti Converse at 702-533-2691 and set up…
Egg Health & Ovarian Reserve Oct 30, 2024

Changes to a 4th cycle

I’m at a bit of a loss. Having ICSI for secondary infertility (1st child conceived naturally age 29) and just midway through my 3rd cycle. I have paid up for a 4th cycle already so I’m keen to get some… — Amy E.

Dr. Geoffrey Sher answered

WE would need to discuss this complex matter. I suggest you call my assistant, Patti Converse (702-533-2691 and set up an online consultation with me. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my…
Egg Health & Ovarian Reserve Oct 28, 2024

Advice for last IVF round

Dear Dr. Sher: Thank you for hosting this forum. I am just shy of 41 with social infertility and have had two failed IVF cycles. The first used an antagonist protocol at 300 IU gonadotropin and resulted in one whole… — Claire C.

Dr. Geoffrey Sher answered

Please read what follows and thereupon, might I suggest that we talk . Please call my assistant. Patti at 702-533-2691 and set up an online consultation with me to discuss. The journey of in vitro fertilization can be a rollercoaster of emotions for many patients. Often times they…
Egg Health & Ovarian Reserve Oct 16, 2024

Adderall for DODR

Hello- I'm hearing a lot about the value of Adderall for patients with DOR and difficulty with implantation. Is there any data for this? What are the risks/benefits? Thank you! — Kristen S.

Dr. Geoffrey Sher answered

Respectfully, to my knowledge there is no data to support this. ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

160 answers

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