– Geoffrey Sher, MD
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Uterine & Endometrial Health
Thanks for taking the time to provide all this info and answer questions on this blog. It's so very much appreciated. We just had a frozen embryo transfer cancelled due to a thin lining and excess fluid in the endometrial… — Mike M.
Dr. Geoffrey Sher answered
A lining
Immunology & Implantation
I am 4+1 week pregnant. Had miscarriages before. I have hashimotos. What test should I do to confirm the autoimmune issue this time. Any suggestions for that? — Farhana A.
Dr. Geoffrey Sher answered
Between 2% and 5% of women of the childbearing age have reduced thyroid hormone activity (hypothyroidism). Women with hypothyroidism often manifest with reproductive failure i.e. infertility, unexplained (often repeated) IVF failure, or recurrent pregnancy loss (RPL). The condition is 5-10 times more common in women than in men.…
Early Pregnancy & hCG
5.8 hcg is it pregnant? how many weeks — Feabe G.
Dr. Geoffrey Sher answered
That is a low level. You need to Repeat the hCG test in 48h of the last one, to see if it at least doubles as it should do! Good luck! Geoff Sher
Early Pregnancy & hCG
17790mIU/mL in HCG blood test means pregnancy positive or negative — Devika N.
Dr. Geoffrey Sher answered
POSITIVE!!
Early Pregnancy & hCG
656 IU/L is good at 4 week 2 days?? — Janbat U.
Dr. Geoffrey Sher answered
Very good. Repeat it in 2 days to see if it (at least) doubles...as it should!
Ovarian Stimulation & OHSS
Dear Dr. Sher, My spouse and I are both 36 years old with unexplained infertility. We've had 6 failed IUIs (4 with letrozole, 1 with letrozole and Menopur, and 1 with Gonal-F). My spouse's AMH is 1.27 ng/mL and AFC… — Gautam J.
Dr. Geoffrey Sher answered
. Obviously there are differences of opinion. What I have espoused is based upon 38Y in the field and >17000babies. The importance of the IVF stimulation protocol on egg/embryo quality cannot be overstated. This factor seems often to be overlooked or discounted by t IVF practitioners who use…
Age & Fertility
Hello Hello, I am not sure my last email went through. we were successful with Elin Fifer being born on 8/28/2013. I am from Colorado and saw you 3 times. Elin is extremely smart and tested a high IQ. she… — Elizabeth A.
Dr. Geoffrey Sher answered
I personally do not see this as an absolute contraindication. The dosage would be the same! I do however suggest you discuss this with a Hematologist. Geoff Sher
Cost & Insurance
Dear Dr. Sher, In 2 days, due to partial DQA match with my husband and weak positive LAD Im going to have LIT in Greece. There are 2 clinics with big differences in price. One does the transfer to my… — Ola K.
Dr. Geoffrey Sher answered
The subcutaneous injection of the male partner’s lymphocytes to the mother is thought to enhance the ability for the mother’s decidua (uterus) to recognize the DQ alpha matching embryo as “self” or “friend” and thereby avert its rejection. LIT has been shown to up-regulate Treg cells and thus…
Age & Fertility
Dear Dr. Sher, thank you very much for all the things you do for our community of fertility warriors. I have heard that gonadotrophins stimulation in older women with low ovarian reserve should only be done with FSH and no… — Shira M.
Dr. Geoffrey Sher answered
It is primarily the egg (rather than the sperm) that determines the chromosomal integrity (karyotype) of the embryo, the most important determinant of egg/embryo competency”. A “competent” egg is therefore one that has a normal karyotype and has the best potential to propagate a “competent” embryo. In turn,…
Embryos & Genetic Testing
I had my first child with no difficulty. followed by 3 losses due to chromosomal issues then went to IVF and had 1 successful birth! We have been trying for the last 4 years and it has resulted in 2… — Tasnem A.
Dr. Geoffrey Sher answered
Your raised TH1: TH2 suggests activated uterine natural killer cells. In your case, having had a child already, this suggests that it is alloimmune rather than autoimmune, immunologic implantation dysfunction (IID). This would require a different approach to treatment. First, however you need to establish a diagnosis. We…
Embryos & Genetic Testing
Hello Dr., I am currently 36 with unexplained infertility. We sought help in 2019 and ended up with a successful IVF cycle, 7 PGS -tested normal embryos (1 day 5 and 6 day 6). We transferred our day 5 embryo… — Natasha B.
Dr. Geoffrey Sher answered
Obviously I cannot with certainty define the cause of your thin lining. I can tell you 2 things: 1. A lining of
Third-Party Reproduction
Using another doner — Mary L.
Dr. Geoffrey Sher answered
Please clarify your question/issue!
I am a colleague of Geoff Sher and i am anxious to contact him . Can you please let me know asap his telephone number or personal email or ask him to contact me directly. This is the second email… — Victor L.
Dr. Geoffrey Sher answered
Hi Victor, So good hearing from you. I do not want to publish my personal contact information on this busy forum. Could you please contact my assistant, Patti Converse at concierge@sherIVF.com or 702-533-2691 and she will provide you with all my contact information. G-d bless! Geoff
Cost & Insurance
Hola doct mi pregunta es ase 8años me operaron. Tube 3niños me deje con mi pareja La doct que me operó me dijo que me habían cortado las trompas y que solo con in vitro podía aserlo cuánto tiempo dura… — Sindy V.
Dr. Geoffrey Sher answered
Please re-post this question in English! Geoff Sher
Embryos & Genetic Testing
I have have had 2 pregnancies, 1 resulted in miscarriage and the other resulted in mono-di girls. I am a permutation fragile x carrier and they have the gene as well. Myself and my husband would like to go through… — Randi T.
Dr. Geoffrey Sher answered
The answer to both questions is yes! Fragile X syndrome occurs in individuals who carry the gene, FMR1 on an X-chromosome. This condition is inherited as a dominant X-linked disorder. With a dominant disorder, the condition results when there is only one copy of the altered gene in…
