Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Answers from our doctors

Search 1,017 questions patients have already asked, or narrow them by topic.

  1. Hormones & Ovulation

    Failed ivf cycle

    Hello doctor; i am 32 yo female, amh 1.59 ng/ml. Partner 32 years old with varicocele, 0 morphology and very low count. (Impossible to check for dna fragmentation) I am Insulin resistant, on metformin 750 for 5 months now with… — Nino K.

    Dr. Geoffrey Sher answered

    There clearly is both male factor infertility and diminished ovarian reserve (DOR). Both issues need to be thoroughly evaluated and addressed. The cause of the male factor will need further testing and the DOR requires a very individualized approach to ovarian stimulation...(see below). I strongly suggest that you…

  2. Embryos & Genetic Testing

    IVF Question

    I'm almost 40 y/o. I've had 4 failed IUIs and two egg retrievals, resulting in only 1 euploid from 47 total eggs retrieved. My fertilization and blast rates are "average" to above average, but my maturity rates are very low.… — Jessica W.

    Dr. Geoffrey Sher answered

    "Empowering Choices: Embryo Banking vs. Egg Banking for Fertility Preservation" It's crucial for women to make informed decisions about preserving their fertility. Delaying trying to conceive, relying on egg freezing, or assuming the biological clock can be paused are misconceptions. As women age, egg quality declines, affecting the…

  3. Age & Fertility

    Question regarding EFS

    Hello. I hope you are well, Dr. Sher. In the rate event that you are reading this, I wanted to see if I might be able to receive your insight. I have just completed my first attempt at egg retrieval… — Kristin B.

    Dr. Geoffrey Sher answered

    Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…

  4. Age & Fertility

    Fiv

    Hola. Tengo 40 años y 0,73 Amh. Me sometí q un ciclo fiv con fostipur 300 y meriofert 150, luego cetrotide, me quedé embarazada pero lo perdí. Me han realizado otro ciclo pero me incluyeron femara y progynova y quitaron… — Rj C.

    Dr. Geoffrey Sher answered

    Please post in English!

  5. Ovarian Stimulation & OHSS

    Inflammation

    Hi Dr. Sher, I had a hscore of 3.4 on Receptiva dx but had a lap done afterwards that showed 0 endometriosis. Why should I lower estrogen with Lupron if there is no endometriosis? — Crystal M.

    Dr. Geoffrey Sher answered

    Respectfully, I do not see a reason! Geoff Sher

  6. Egg Health & Ovarian Reserve

    Unexplained infertility

    Greetings! I am a 39yo f, pmhx prolactinoma (dx 1/2023, medically managed now), ulcerative proctitis (on stelara, almost in remission) with 1 natural conception and loss at 8 weeks due to trisomy, now 3 failed IVF stim attempts. My AMH… — Lindsey A.

    Dr. Geoffrey Sher answered

    In my opinion, we need to have a detailed online consultation to discuss the following issues in detail: 1. Egg/embryo quality issues: and the influence of the protocol used for ovarian stimulation as well as diminishing ovarian reserve and advancing age.. 2. Implantation dysfunction as it might relate…

  7. Ovarian Stimulation & OHSS

    Sobre la estimulación ovarica

    Doctor ayúdeme tengo miedo de haber malogrado mi estimulación ovarica, en mi última inyección que era de ovidrel de 250, no supe ponérmela la inyecte dos veces porque no había puesto la dosis correcta y me di cuenta después de… — Isa F.

    Dr. Geoffrey Sher answered

    Please re-post this in English and I will respond promptly! Geoff Sher

  8. Early Pregnancy & hCG

    withdrawal bleeding during estrogen and progesteron supplementation a week after FET

    Dear Dr.Sher. I am an ENT doctor from Europe. I am diagnosed with PCOS and I have amenorrhea and no ovulation at all. One year ago my fertility doctor prescribed me Letrozol, because I wanted to conceive. Not only that… — Maria K.

    Dr. Geoffrey Sher answered

    It could be an implantation dysfunction due to another thin endometrium (endometrial insufficiency, Back in 1989, I conducted a study that examined how the thickness of a woman's uterine lining, known as the endometrium, affected the successful implantation of embryos in IVF patients. The study revealed that when…

  9. IUI & Insemination

    Seeking advice – IUI + letrozole

    Hi Dr. Sher, I listened to the podcast on IUI with you and Dr. Aimee, the egg whisperer and I wanted to reach out to you in hopes of seeking your advice. I am a 34 year old who is… — Mallory F.

    Dr. Geoffrey Sher answered

    My bigger concern is that you might have an immunologic inmmplantation dysfunction and if so , IUI alone wont bve effective. This could explain your losses too. Between 2% and 5% of women in their childbearing years deal with hypothyroidism, a condition that affects women more than men.…

  10. Egg Health & Ovarian Reserve

    Stimulation poor responder

    Advice on stimulation proctol please. Background: I’m 36y, normal BMI, pelvic and bowel endometriosis (lap confirmed and excised), high activated NK cells, persistently raised cardiolipin IgM titre, 3+ yr history primary infertility.5 failed embryo transfers. I did have brief chemical… — Maya G.

    Dr. Geoffrey Sher answered

    A. Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing…

  11. Egg Health & Ovarian Reserve

    Mistake on one dosage

    Hi Dr Sher, On the 5th day of my FSH treatment with Gonal-F only, I made a mistake and used Pergoveris instead of Gonal-F (same dosage), It's the same follitropin alfa, but I am afraid of the LH surge, that… — Jennifer S.

    Dr. Geoffrey Sher answered

    I don't think it will be a problem. I would not cancel...but discuss with your own RE. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your…

  12. Hormones & Ovulation

    Ovidrel dosage on low BMI

    Dear Dr. Sher, I am low BMI. Should I do 500mcg hCGr for trigger or is 250mcg enough? Thanks again for all the help, A.C. — Anne C.

    Dr. Geoffrey Sher answered

    500mcg Ovidrel! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions…

  13. Egg Health & Ovarian Reserve

    Omnitrope dosage

    Dear Dr. Sher, Should Omnitrope continue to be taken on the day of the trigger and the next day, all the way till egg retrieval day, or stop two days before, when FSH stops? And what's the optimal dosage? Thanks… — Anne C.

    Dr. Geoffrey Sher answered

    No! It stops on the day of the "trigger". Good luck! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro…

  14. Egg Health & Ovarian Reserve

    Empty follicles

    I am currently 33 years old and have already had 3 ICSIs. However, the first one was 5 years ago. Last year I stimulated for 2 days with 375 Gonal f and 75 Menopur and then with 225 Gonal f… — Monika O.

    Dr. Geoffrey Sher answered

    “Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely to happen when multiple attempts are needed to retrieve an egg from a follicle, indicating the egg may have chromosomal abnormalities. The…

  15. Ovarian Stimulation & OHSS

    Endometrial cavity fluid

    I’ve had ECF ever since a d&c and forcep removal of rpoc in Jan 2022. I’ve taken prophylactic abx, hysteroscopy with loa and normal lap, 2.5 months lupron and letrozole for adeno. Failed medicated FET. 1) should I do a… — Arielle M.

    Dr. Geoffrey Sher answered

    There is too much here to discuss with a short response. We should talk. If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or email her at

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