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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Search 1,006 questions patients have already asked, or narrow them by topic.

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  1. Egg Health & Ovarian Reserve

    “Empty follicles”

    Dr. Sher, I have a problem with my right ovary. Every time if we have more than one follicle > 17 mm in diameter on this side, we cannot retrieve the eggs (experienced that 3 times). We tried multiple protocols,… — Patricia K.

    Dr. Geoffrey Sher answered

    I suggest you call my assistant "Patti" (702-533-2691) and set up an online consultation with me to discuss...see below. EMPTY FOLLICLE SYNDROME” “Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely…

  2. Egg Health & Ovarian Reserve

    Bad quality eggs

    Dear Dr. Sher. I am out of options i feel. Unknown fertility problem, endometriosis. I am now 30 years old. For the last 5 years: 5 IVF/ICSI cycles, 65 mature eggs, 30 fertilized, 0 good blastocyst, only poor quality, nothing… — Maggy M.

    Dr. Geoffrey Sher answered

    Embarking on the journey of IVF often raises questions about the likelihood of success and the quality of embryos. While it’s challenging to predict outcomes due to various factors, there’s hope and information to guide you. Firstly, the key to fertilization potential lies in the chromosomal integrity of…

  3. Egg Health & Ovarian Reserve

    poor egg quality

    Im 37F no other medical history. AMH 2.01, Day 3 FSH 5.7, estradiol 56. Have done two cycles of IVF: First cycles I was on menopur (150) and gonal (initially 150 and bumped to 300) for about 11 days with… — Serena B.

    Dr. Geoffrey Sher answered

    In my opinion, you are young enough and have a normal ovarian reserve, such that egg quality should not likely be an inherent problem. In such cases, it is very often the protocol used for ovarian stimulation that plays a role here. It needs to be individualized to…

  4. Embryos & Genetic Testing

    Failed FET

    Hi Dr. Sher, You did my egg retrieval 3 years ago, and we welcomed our beautiful daughter 2 years ago. We just did another transfer of 1 pgt embryo for a baby boy, and it failed. We only have 1… — Megan L.

    Dr. Geoffrey Sher answered

    We should talk. Please call my assistant, Patti (702-533-2691) and set up an online consultation to discuss. Geoff Sher

  5. Egg Health & Ovarian Reserve

    Same Agonist/Antagonist Conversion Protocols with Very Different AFC 6 Months Apart

    Dr. Sher, I convinced my IVF doctor to let me use your agonist/antagonist conversion protocol with Zomacton (using Ganirelix to replace Lupron and keep using it until trigger date). My March cycle resulted in 4 eggs retrieved, 3 fertilized, unfortunately… — Meredith S.

    Dr. Geoffrey Sher answered

    There can be a very rapid decline in AFC at your age . This is because of inevitable decline in ovarian reserve and in egg quality. If you wish, you coulkd call my assistant Patti Converse at 702-533-2691 and set up an online consultation with me to discuss…

  6. Egg Health & Ovarian Reserve

    Protocol for second round after low maturity in the first

    Hi Dr Sher, We recently embarked on IVF after 1x TFMR at 24 weeks for genetic disorder (22q syndrome) of which neither me or my partner are carriers followed by 3x chemical miscarriage around 4.5/5 weeks. Our first cycle was… — Victoria L.

    Dr. Geoffrey Sher answered

    We should talk. There is no doubt in my my mind that the protocol used for ovarian stimulation has to be individualized to optimize egg/embryo "competency. I invite you to call 702-533-2691 and ask my assistant, Patti Converse, to set up an online consultation with me to discuss.…

  7. Egg Health & Ovarian Reserve

    CoQ10

    I am 43 years old with AMH of 3. My egg retrieval was yesterday. My HCG trigger did not absorb after 7 days of Stims and no priming starting on day 5 of my period. I was given 150 meno… — Kristin H.

    Dr. Geoffrey Sher answered

    The COQ10 likely had nothing to do with your follicle development. However, the protocol used for ovarian stimulation and/or its implementation, probably underlies your issue.We should talk: Please call my assistant, Patti Converse (702-533-2691 and set up an online consultation with me. EGG/ EMBRYO QUALITY IN IVF &…

  8. Egg Health & Ovarian Reserve

    Protocol

    Hi, I am 44 with an Amh between 2.3 and 3 ng/ml, we had failed Icsis but always blastocysts. Would you also recommend the protocol you normally describe here or at the egg whisperer podcast in my case? Last year… — M M.

    Dr. Geoffrey Sher answered

    Your normal AMH at 44y comes as a surprise but that is decidedly in your favor. However, independently, age impacts egg "competency" and it is the egg (rather than the sperm that is most important in propagating normal "competent" embryos. Age should never be a barrier to hope…

  9. Ovarian Stimulation & OHSS

    Trigger shot

    Why is a 10,000 HCG trigger better than a 5,000 my clinic recent triggered me with only 5,000 and they say I have DOR. We also did a mini stim with letrozole and menopure. Which I am reading you don’t… — Vern T.

    Dr. Geoffrey Sher answered

    To optimize response, all available hCG receptors in the cells of the follicle should be occupied to insure an optimal response. In many cases, 5,000U hCG wont do the trick. Since there is no down-side or risk in giving 10,000U there is n in my opinion safer to…

  10. Ovarian Stimulation & OHSS

    Agonist/antagonist conversion protocol

    Hello, I am a patient with DOR at ACFS in Scottsdale, AZ. Would you be willing to send me the written agonist/antagonist conversion protocol in detail so my doctor can follow it? I am 34 with an AMH of 0.8… — Kathleen T.

    Dr. Geoffrey Sher answered

    I cannot post a detailed protocol here. Your Re is free to call us to discuss this at will (702-533-2691). ADDRESSING DIMINISHING OVARIAN RESERVE (DOR) IN IVF Understanding the impact of ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive…

  11. Egg Health & Ovarian Reserve

    Ivf low responder

    Dear Dr. Sher, I am in my late 30s and have an amh of 0,3. My period is very regular with regular ovulation (day 11 to 13) and I do not have any problems in the luteal phase like spotting.… — Sandra W.

    Dr. Geoffrey Sher answered

    I think I can help here! Please see my repose to your 2nd post...Same recommendation applies...We should talk. Geoff Sher

  12. Embryos & Genetic Testing

    Frozen embryo transfer add on

    Hello Dr. Sher, Hope you are doing well.. 1. What is your view about hcg booster shots between ovulation induction and transfer for modified natural transfer? Does it have positive effect on endometrium before transfer? If yes what will be… — Sreevidhya V.

    Dr. Geoffrey Sher answered

    What is your view about hcg booster shots between ovulation induction and transfer for modified natural transfer? Does it have positive effect on endometrium before transfer? If yes what will be the ideal protocol and dose for hcg booster? A: I do not advocate this! 2. What is…

  13. Embryos & Genetic Testing

    2nd opinion

    Hi. Is it possible to get a second opinion on my IVF process? I'm located in Philadelphia and won't be getting IVF at your clinic. I just wanted to find out Dr. Sher's opinion about my IVF protocols and what… — Kseniya F.

    Dr. Geoffrey Sher answered

    Please call Patti at 702-533-2691 or email her at concierge@sherivf.com and set up an online consultation with me. Geoff Sher EGG/ EMBRYO QUALITY IN IVF & HOW SELECTION OF THE IDEAL PROTOCOL FOR OVARIAN STIMULATION INFLUENCES EGG/EMBRYO QUALITY AND OUTCOME. The journey of in vitro fertilization can be…

  14. Immunology & Implantation

    IVF medication regiment

    I am seeing Dr Klitz at Cny fertility. I have had two filled IUI and two filled IVF. I have no health history besides a tilted uterus. My husband, sperm mythology is low and abnormal, but does have some normal… — Victoria S.

    Dr. Geoffrey Sher answered

    If you've undergone in vitro fertilization (IVF) and didn't achieve a successful pregnancy, you may be wondering why. It's important to know that IVF outcomes can be unpredictable, but there are factors that can affect your chances. Let's explore some common reasons for IVF failure in simpler terms.…

  15. Egg Health & Ovarian Reserve

    HGH for DOR

    I have read about increasing primordial follicles and thus increasing the antral follicle count by using HGH for 70 days, after ovarian PRP. Is there long term affects for the mother either during use of HGH or from withdrawal affect… — Kristina L.

    Dr. Geoffrey Sher answered

    This is very controversial. I am not at all convinced of its benefit! Geoff Shert

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