– Geoffrey Sher, MD
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Embryos & Genetic Testing
I have done an I VF and I am right now in the two week wait anxiety . I have tried 4 times previously and have a failure . The doctor this time did surgical scratching for the uterus ,… — Monica E.
Dr. Geoffrey Sher answered
I suggest you await the outcome and if you do not conceive, that you contact my assistant Patti Converse (702-533-2691) and set up a consultation online, with me. Good luck! Geoff Sher
Embryos & Genetic Testing
I'm 36 and doing IVF with PGT-A and PGT-M to avoid passing on a genetic condition I'm a carrier for. I don't have any identified fertility issues and have had a viable natural pregnancy before at age 34. I've had… — Charlotte D.
Dr. Geoffrey Sher answered
Frankly, you and I should have an in depth discussion to address these issues. I do not believe there is merit in transferring day 7 blastocysts whether or not they are euploid. The chance of pregnancy is dismal. There could be embryo issues relating to a possible deficiency…
Embryos & Genetic Testing
Hi Dr Sher. I am from New Zealand and almost 2 years on in my fertility journey. I’m 42 now and have 3 children of my own. My husband has 1. We are both fit and healthy. I’ve always had… — Barbara C.
Dr. Geoffrey Sher answered
Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is why! Was it simply due to, bad luck?, How likely is the failure to recur in future attempts and what can be done differently, to avoid it happening next time?.…
Embryos & Genetic Testing
Hello Dr. I have had 3 MCs ( chromosome issues) 3 rounds of er, in total 34 eggs, 23 fertilized, 5 blasts no euploid, 1 failed fresh 3-day transfer. I am 40 started all this when I was 38. My… — Desiree B.
Dr. Geoffrey Sher answered
There is really a great deal to talk about here. I strongly urge you to call my assistant Patti at 702-533-2691 and set up an online consultation with me. Given your history of 3 losses I think that aside from an egg/embryo quality issue you could, in addition,…
Clinic & Practice
Dr. Drew - we have been working with another clinic and are pretty upset with them - we have 6 embryos and just found out the lab - Igenmonix - destroyed all samples. Our friend is a patient of yours.… — Tanya G.
Dr. Geoffrey Sher answered
You have posted on my board. I suggest you re-post on that of Dr Tortoriello! Geoff Sher
Embryos & Genetic Testing
Hi! I would like to book a consultation and consider next steps. I did two precision IVF and the transfer failed. Genetically normal embryos. I’m trying to figure out if seeing a RI would be worth it. I’m open to… — Gloria K.
Dr. Geoffrey Sher answered
When women with infertility due to endometriosis seek treatment, they are all too often advised to first try ovarian stimulation (ovulation Induction) with intrauterine insemination (IUI) ………as if to say that this would be just as likely to result in a baby as would in vitro fertilization (IVF).…
Embryos & Genetic Testing
Just wondering if you see any pitfalls in doing a simple oestrogen/progesterone protocol. I asked about adding in prednisolone, as a precaution. But the clinic is not keen using steroid medications- such as prednisolone, in patients who do not necessarily… — Cassidy C.
Dr. Geoffrey Sher answered
Perhaps we should talk! 702-533-2691
Embryos & Genetic Testing
Good afternoon dear doctor! I am 42 years old, after 8 hormonal stimulations, I have a single mosaic embryo. Blastocyst 7 days. I need to decide an important question whether to transfer it or not. Embryo seq(3)x1~2,(6)x1~2. Mosaic monosomy of… — Olga M.
Dr. Geoffrey Sher answered
I would not advise using this embryo! Human embryo development occurs through a process that encompasses reprogramming, sequential cleavage divisions and mitotic chromosome segregation and embryonic genome activation. Chromosomal abnormalities may arise during germ cell and/or preimplantation embryo development and represents a major cause of early pregnancy loss.…
Embryos & Genetic Testing
We have an extra embryo to donate to another couple or science. What are our options? — Patrick R.
Dr. Geoffrey Sher answered
Please call 646-792--7476 and ask for Bushra Sudal RN. She will be glad to assist you.
Egg Health & Ovarian Reserve
Hi Dr. Sher, I am asking this question after first egg retrieval. I am 40 years old, first time doing this IVF. I saw about 23 follicles during ultrasound and was on 21 days lupron protocol ended with 20 eggs,… — Esther L.
Dr. Geoffrey Sher answered
The importance of the IVF stimulation protocol on egg/embryo quality cannot be overstated. This factor seems often to be overlooked or discounted by t IVF practitioners who use a “one-size-fits-all” approach to ovarian stimulation. My experience is that the use of individualized/customized COS protocols can greatly improve IVF…
Embryos & Genetic Testing
Im looking to have a girl for my third pregnancy after having 2 boys. I have had no fertility issue and for both my kids I got pregnant in my first try. Do you have any gender selection service? Like… — Maryam F.
Dr. Geoffrey Sher answered
Couples have for centuries sought to influence the gender of their offspring. More than seven centuries ago the ancient Chinese developed a birth calendar said to be able to predict gender on the basis of when conception occurred. Later, the ancient Greeks suggested that by lying on her…
Embryos & Genetic Testing
Dear Dr. Sher, Do you recommend Sildenafil 4x 25mg/day during the follicular phase or only when the embryo transfer is scheduled? Do you recommend Sildenafil although there are no previous evidences of lack of thickening of the endometrial walls? Thank… — Ola
Dr. Geoffrey Sher answered
Yes…only in the follicular phase but not in the absence of an endometrial thickness issue! Geoff Sher
Embryos & Genetic Testing
I need your advice. I have had two failed embryo transfers. I had my embryos PGT tested and they were normal and very high-quality embryos. I am 37 years old with no underlining health conditions. But maternal history of endometriosis.… — Vanessa A.
Dr. Geoffrey Sher answered
antibodies (APA) that can compromise development of the embryo’s root system (trophoblast). In addition and far more serious, is the fact that in about one third of cases endometriosis, regardless of its severity is associated with NKa and cytotoxic uterine lymphocytes (CTL) which can seriously jeopardize implantation. This…
