The question
I'm 36 and doing IVF with PGT-A and PGT-M to avoid passing on a genetic condition I'm a carrier for. I don't have any identified fertility issues and have had a viable natural pregnancy before at age 34. I've had a two normal saline songrams and everything else looks good on paper for my age. But, my husband was found to have high double strand DNA fragmentation - although not so high that we couldn't use Zymot. I have two Day 6 euploid embryos and two Day 7 euploid embryos from 3 cycles of IVF. We've had early blastocysts on Day 5 but never anything that's more progressed than that. Our embryos seem to grow more slowly, but we are able to produce euploids.
Could slow embryo development (either due to my age or husband's sperm) mean that our embryos are less likely to work despite being euploid?
Also, what is your opinion on Day 7 euploids?
Answer from Dr. Geoffrey Sher
Frankly, you and I should have an in depth discussion to address these issues. I do not believe there is merit in transferring day 7 blastocysts whether or not they are euploid. The chance of pregnancy is dismal.
There could be embryo issues relating to a possible deficiency in the protocols used for ovarian stimulation and/or there could be implantation issues as well.
I suggest you contact my assistant, Patti Converse at 702-533-2691 and set up an online consultation with me.
Geoff Sher
General information only, not medical advice for your own situation. For that, book a consultation.