Infertility is defined as inability to conceive in spite of engaging in well-timed unprotected sex for more than one year. The causes of infertility are multiple and are often difficult to define but may include anatomical conditions involving tubal patency and/or function as well as diseases of the testicles and/or or sperm ducts, dysfunctional levels […]
Causes of Infertility Read More »
Cryopreservation of human embryos has been a routine procedure since the early 1980s. Until quite recently, it involved a “conventional” slow freezing process which unfortunately resulted in intracellular ice crystal formation which damaged embryos, destroying some and reducing the ability of most to propagate viable pregnancies. pregnancy. The introduction over the last 10-15 years of
Because of the emotional, physical, and financial toll exacted by IVF, it is preferable that no one undertake a one‑shot attempt. If a couple can only afford one treatment cycle, IVF is probably not the right course of action. After all, with conventional IVF there is only about one chance in three that it will result in a live birth ‑and a tremendous letdown if it fails. It is thus unreasonable to undergo IVF with the attitude that “if it doesn’t work the first time, we’re giving up.” In vitro fertilization is a gamble even in the best of circumstances.
IVF Using Own Eggs : When is it Time to Move on? Read More »
_WHEN IT COMES TO THE SELECTION OF OVARIAN STIMULATION PROTOCOLS FOR
OLDER WOMEN AND THOSE WHO HAVE DOR THERE IS IN MY OPINION, NO
JUSTIFICATION FOR THE USE OF A “ONE SIZE FITS ALL” OR “RECIPE
APPROACH”. I FIRMLY BELIEVE THAT THE TIME HAS ARRIVED TO REFLECT
SERIOUSLY ON AN INDIVIDUALIZED SELECTION OF OVARIAN STIMULATION
PROTOCOLS THAT WOULD OPTIMIZE EGG/EMBRYO QUALITY, RATHER THAN SIMPLY
TRYING TO MAXIMIZE THE TOTAL EGG YIELD._
A woman is bo…
This interview originally ran on The Egg Whisperer Show with Dr.
Aimee.
TO WATCH THE EPISODE, AND LEARN MORE, PLEASE VISIT HER WEBSITE AT
HTTPS://DRAIMEE.ORG/HOW-TO-AVOID-IMPLANTATION-FAILURE-DURING-IVF-WITH-GUEST-DR-GEOFFREY-SHER
How to Avoid Implantation Failure During IVF with Dr. Geoffrey Sher Read More »
All humans have two DQ-alpha genes, one of which is contributed by the
father and the other by the mother. In a small percentage of patients
undergoing IVF, paternal-maternal DQ-alpha gene similarities occur. In
such cases, following repeated exposures to such genetically matching
embryos, this will provoke activation of the decidual immune system.
In most cases, repeated exposure to DQ alpha matching embryos will
over time activate uterine NK cells, resulting in reproductive dy…
In order for any organism to attain an optimal state of maturation
(ripening) it must first undergo full growth and development. A fruit
plucked from a tree before having developed fully or a poorly
developed fruit might still ripen (mature) on the shelf and might even
appear as enticing as one that had previously undergone proper
development, but it will lack the same quality. The same principles
apply to the development and maturation of h…
Controlled Ovarian Stimulation (COS) for IVF: Selecting the ideal protocol Read More »
_Ovarian reserve_ is the term used to describe the extent of a
woman’s ovarian egg supply. Diminished ovarian reserve (DOR) refers
to a reduction in the total number of eggs left in the ovaries such
that resistance builds to ovarian stimulation with fertility drugs.
With progressively diminishing ovarian reserve, an ever increasing
amount of fertility drugs is required to stimulate optimal follicle
and egg development…
Diagnosing and Treating Infertility due to Diminished Ovarian Reserve (DOR) Read More »
Thrombophilia (Hereditary Clotting Defect) is defined as the genetic
predisposition to developing intravascular thrombosis. It is due to
hypercoagulability of blood leading to impairment of initial
vascularization that takes place during implantation.
Thrombophilia affects as many as one in five people in the United
States and is responsible for pregnancy loss (most particularly after
the 1st tri…
Hereditary Clotting Defects (Thrombophilia) Read More »
The potential for a woman’s eggs to undergo orderly development and
maturation, while in large part being genetically determined can be
profoundly influenced by the woman’s age, her “ovarian reserve”
and proximity to menopause. It is also influenced by the protocol used
for controlled ovarian stimulation (COH) which by fashioning the
intra-ovarian hormonal environment, profoundly impacts egg development
and maturation.
