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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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214 answers

Uterine & Endometrial Health

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Egg Health & Ovarian Reserve Oct 30, 2023

Reoccurring failed implantation

Hi Dr. Sher, I found your website after researching pgt embryos that fail to implant. I’m 38 years old, I have DOR, AMH .5 when tested a year ago, FSH 10.3. I did three retrievals and ended up with 5… — Jill D.

Dr. Geoffrey Sher answered

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Hormones & Ovulation Oct 26, 2023

Repeated Miscarriage

Hi Dr. Sher, Thanks so much for taking the time to read and answer our questions, and for the valuable resources on your site. I have PCOS and have had 4 losses, no live births yet. Each miscarriage at a… — Irma M.

Dr. Geoffrey Sher answered

When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
Ovarian Stimulation & OHSS Oct 20, 2023

If I miss a day of my Buserelin injection

Hi, am currently going through an IVF process and I have been taking my injection since the 8th and it'll continue till next month but I realized this morning that I forgot to do my injection yesterday and also forgot… — Blessing A.

Dr. Geoffrey Sher answered

Without knowing your case and your diagnosis, I cannot respond authoritatively. You will need to talk to your treating doctor.. Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A…
Uterine & Endometrial Health Oct 20, 2023

Viagra vaginal insertion

Please, can Viagra help grow my uterine lining,i did Hysteroscopy 4 months ago and my doctor just prescribed Viagra to help my womb before Embryo transfer. Thank you. — Okeoma N.

Dr. Geoffrey Sher answered

Back in 1989, I conducted a study that examined how the thickness of a woman's uterine lining, known as the endometrium, affected the successful implantation of embryos in IVF patients. The study revealed that when the uterine lining measured less than 8mm in thickness by the day of…
Embryos & Genetic Testing Oct 18, 2023

SET vs. DET

I read through your website in your opinion of how many embryos to transfer. Would your recommendation change in the case of multiple failed euploid transfers in someone under 35? I have done all of the recommended testing and have… — Tasha T.

Dr. Geoffrey Sher answered

If multiple euploid embryo transfers have failed, you likely have an implantation dysfunction and it wont matter whether you transfer 1 or 2 embryos...outcome would be the same. What is needed is ti identify and address the cause of the implantation failure (see below). IVF FAILURE WITH “NORMAL”…
Uterine & Endometrial Health Oct 16, 2023

progesterone in the days prior to FET

atiI took an extra progestrone shot (1 ml) in the morning 4 days prior to my scheduled FET. I'm supposed to take in the evening (yesterday was my first day on progesterone injections and the clinic had me take one… — Mary M.

Dr. Geoffrey Sher answered

I wish I could help but you need to discuss this directly with your treating doctor! Sorry! Geoff Sher
Hormones & Ovulation Oct 9, 2023

Do Intralipids in IVF cause weight gain

I am 37, have low egg count and poor egg quality in the last 3 egg retreivals. There is mild adenomyosis and possible endometrioma on my scans. I don’t have any known autoimmune conditions. My fertility specialist feels I might… — Michaela T.

Dr. Geoffrey Sher answered

It should not cause weight gain. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) ; http://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf Recurrent Pregnancy Loss and…
Ovarian Stimulation & OHSS Sep 25, 2023

Why is Lupron decreased

Hi there, I was wondering why you decrease the dosage of Lupron once the Estrogen begins? I struggle with a thin endometrium lining and was reading your protocol for FET. I was wondering if the reason why my lining may… — Tracy W.

Dr. Geoffrey Sher answered

Frankly , little to no Lupron is needed once the estrogen therapy begins. A thin uterine lining can have numerous causes. Back in 1989, I conducted a study that examined how the thickness of a woman's uterine lining, known as the endometrium, affected the successful implantation of embryos…
Uterine & Endometrial Health Sep 25, 2023

Lining 1 week prior to transfer

Hello I’m concerned because my ultrasound yesterday 9-22 had my lining at 6.2. My doctor gave me the green light to continue but I’m worried my lining isn’t good enough to go through the transfer and I can’t afford to… — Rachel R.

Dr. Geoffrey Sher answered

Respectfully, I would not do an ET with a lining
Uterine & Endometrial Health Sep 17, 2023

Wrong Progesterone Dosage!!

Hello Dr.S I am in full on panic mode. I am 5 weeks 3 days pregnant. I am supposed to be taking 400 mgs of prog (suppositories) 200 mgs x 2 daily. I just realized that the clinic accidently gave… — Hannah H.

Dr. Geoffrey Sher answered

I can understand your concern/confusion...but respectfully, I think 100-200mg daily is quite adequate. Sincerely, Geoff Sher
Early Pregnancy & hCG Sep 15, 2023

hcg and progesterone halved value in 2 days

On 12 dpt, hcg level was in 300 and Progesterone was in 90s.. 2 days later, HCG level halved and so did progesterone... I know I have to wait for next lab.. I'm scared... would I be losing this? — N B.

Dr. Geoffrey Sher answered

Sadly, this does not look good! Sorry Geoff Sher
Early Pregnancy & hCG Sep 10, 2023

Progesterone dropped at 6-7 weeks while on pessaries

Hi Dr Sher, Im currently 7 weeks pregnant and beta hcg was last measured at 6+5 weeks and was 35000. However, my progesterone has dropped from a high of 73nmol (about 22ng) to 50nmol (around 16ng). This drop has come… — Dani C.

Dr. Geoffrey Sher answered

I really do not believe this will be an issue. A P4 of 16ng/ml at this stage is still adequate. Good luck! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY…
Uterine & Endometrial Health Sep 9, 2023

Lubion injections of progesterone

Hello Dr Sher, I hope you’re well. I am pleased to say that I got my first pregnancy confirmed on Monday, beta levels/ rises are healthy so far. I’m using Lubion instead of PIO for progesterone support and I’m concerned… — Cassidy O.

Dr. Geoffrey Sher answered

Congratulations Cassidy, The needle size (although unnecessarily large) will in no way adversely effect delivery of the medication or outcome. Good luck! Geoff Sher
Uterine & Endometrial Health Sep 4, 2023

Progesterone Timing and Receptivity

Hi Doctor. I am worried about my uterine receptivity and progesterone exposure. I'm in the TWW after a modified natural cycle. On a Monday my follicle was 17mm. and my doctor told me to trigger the next day not expecting… — Albena T.

Dr. Geoffrey Sher answered

I do not think the surge or the "trigger" with Ovidrel will change the timing of the FET. But to be quite honest, I personally prevent FET's in hormone replacement cycles to better pinpoint the ideal window of implantation. Prior to 2 decades ago, most women undergoing IVF…
Infertility Basics Sep 1, 2023

Unexplained infertility

Hi Dr Sher, Having heard some of your talks online, I felt reinvigorated and am now determined to find out the cause of my infertility. I am 25 years old and my husband is 29. We had been trying for… — Layla A.

Dr. Geoffrey Sher answered

Given your age and history, I would not be at all surprised if this were an implantation dysfunction (possibly immunologic). See the urticles below . In my opinion, you should delay doing another FET until there is a diagnosis. Infertility affects y 10%-15% of couples who are unable…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

214 answers

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