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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Search 1,006 questions patients have already asked, or narrow them by topic.

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  1. Egg Health & Ovarian Reserve

    Am I a lost cause?

    Dear doctor Sher, I am 33 years old and my husband is 36. After 5 months of trying to conceive (that was back in November 2022), we decided to visit a fertility specialist in Switzerland where we are currently located.… — Alexandra C.

    Dr. Geoffrey Sher answered

    Hi Alexandra, Yes indeed, based on your AMH blood level, you have prematurely developed diminished ovarian reserve (DOR) and this means you have very much reduced egg population (which cannot be replenished) and accordingly will propagate very few follicles. In addition, women with DOR often have an adverse…

  2. Hormones & Ovulation

    2 failed cycles, No transfer

    Hi Dr Sher I’m a 30 year old living in London. I have had 2 IVF cycles, but after both, all embryos stopped growing after 2-3 days post egg retrieval. I was also told I have mild PCO in my… — Abi S.

    Dr. Geoffrey Sher answered

    Very respectfully, this is not likely to be a uniform genetic issue. More than likely ity has to do with the protocol used for ovarian stimulation (see below). The importance of the IVF stimulation protocol on egg/embryo quality cannot be overstated. This factor seems often to be overlooked…

  3. Egg Health & Ovarian Reserve

    Hormone levels during IVF

    I am 36 years old and only freezing eggs. My AMH was just over 1 ng about a year ago, AFC usually 6-8. I have a long history of stage 4 endometriosis. 1. Could a disproportionately high estrogen to follicle… — Lilly G.

    Dr. Geoffrey Sher answered

    I do not believe tyhat an E2 of 3000pg/ml at peak, is potentially harmful. This having been said, the protocol used for ovarian stimulation is important, but without much more information in this regard, I cannot comment authoritatively. Av separate issue is the effect of endometriosis on IVF…

  4. Hormones & Ovulation

    2 Failed FETs

    Hi Dr Sher, first of all thank you for taking the time to read my question. I am 35 years old, and I just had my 2nd failed FET. On both occasions we transferred a 5aa hatching embryo non PGT… — Alisa W.

    Dr. Geoffrey Sher answered

    I think we should talk. P)lease consider calling my assistant, Patti Converse at 702-533-2691 to set up an online consultation with me. Geoff Sher Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is why! Was it simply due to,…

  5. Age & Fertility

    Pcos, AMH and menopause?

    Hello Dr. I am turning 40 this year and have pcos. Can you explain why my AMH is still very high? 12 years ago it was 10 ng/ml, now it’s 6.85. I also used to have 15 follicles on each… — Amanda B.

    Dr. Geoffrey Sher answered

    It ism true thatvwo9men with PCOS have an increased risk of developing breast and ovarian cancer. However, this is by no means a great risk. You need to have regular check-up evaluations at least yearly, but I would not become paranoid about this. In the vast majority of…

  6. Hormones & Ovulation

    IVF failure 1x

    I just went through my 1st IVF transfer on 2/15/23, I have found out I failed. My uterus lining was 9+ , Embryo was 4AA. I am wondering if it’s my natural killer cells. I had Endometriosis and a Septate… — Marisa T.

    Dr. Geoffrey Sher answered

    Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is why! Was it simply due to, bad luck?, How likely is the failure to recur in future attempts and what can be done differently, to avoid it happening next time?.…

  7. Hormones & Ovulation

    BMI limit

    Is there a bmi limit for IVF treatment? — Christie C.

    Dr. Geoffrey Sher answered

    Not really! ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “ http://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf “Recurrent Pregnancy Loss and Unexplained…

  8. Hormones & Ovulation

    Fertility Inducing Medications

    Hello! Do you use BMI as a metric for prescribing fertility inducing medication (Clomid/letrozole)? If so, what is the maximum BMI allowed? Thank you! — Audrey V.

    Dr. Geoffrey Sher answered

    No! By and large, I do not! Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS)…

  9. Hormones & Ovulation

    Laparoscopic Surgery or IVF?

    I’m 31 with secondary infertility and been trying for 4 years with my husband. Three years ago I was diagnosed with hypothyroidism, hashimotos, pcos (before I was diagnosed I did 5 rounds of letrozle, and one IUI) and now endometriosis?… — Rachel B.

    Dr. Geoffrey Sher answered

    Unless the laparoscopy is intended to alleviate symptoms by ablating lesions, freeing pelvic adhesions or removing an ovarian endometrioma, I would NOT go that route. I would do IVF. When women with infertility due to endometriosis seek treatment, they are all too often advised to first try ovarian…

  10. Hormones & Ovulation

    Trigger using HCG10,000 and Decapeptyl

    Hi Dr Sher, my RE has asked me to trigger with both HCG 10,000 and Decapeptyl 1 ml. I find this strange. I understand that Dual Trigger is considered for cases where there might be risk of OHSS, but I… — Jenna H.

    Dr. Geoffrey Sher answered

    Respectfully, I do agree with you, but this is something you need to discuss with your treating RE “Triggering” Egg Maturation in IVF: Comparing urine-derived hCG, Recombinant DNA-hCG and GnRH-agonist: Geoffrey Sher MD Ideal egg development sets the scene for optimal egg maturation that occurs 36-42h prior to…

  11. Hormones & Ovulation

    Dropping LH Levels, no ovulation yet but growing follicles

    Hi Dr. I am undergoing a few rounds of cycle monitoring with medicated timed intercourse while I wait for my turn for funded IVF ( I live in Canada). I took Letrozole on days 2-6 of my cycle and went… — Jackie B.

    Dr. Geoffrey Sher answered

    Letrozole increases blood LH. Geoff Sher ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) “ http://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf “Recurrent…

  12. Hormones & Ovulation

    Clarification on Article

    Can I please get clarification on what this means: Churchill and Comstock (2017) conclude:" In our preliminary observations, the non- receptive ERA group had similar live birth rates compared to the receptive ERA group. It appears the majority of the… — Jamie B.

    Dr. Geoffrey Sher answered

    Endometrial Receptivity Array (ERA): Is There an actual There, There? Geoffrey Sher MD The blastocyst and the endometrium are in a constant state of cross-talk. In order for successful implantation to take place, the blastocyst must be at the appropriate stage of development, and needs to signal a…

  13. Hormones & Ovulation

    38 and ovulation infection meds

    I’m 38 years old and having difficulty conceiving. I developed Ashermans (moderate) in 2020. I got lysis of adhesions and conceived my daughter shortly after at 36 years old. I ovulate and haven’t regular cycles. My doctor is giving me… — Sarah E.

    Dr. Geoffrey Sher answered

    Respectfully, . After Ashernan's, endometrial thickness poses a real problem in many cases. In my opinion, Tamoxifen will make matters worse as far as the uterine lining is concerned. Look this up in my book, From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS)…

  14. Egg Health & Ovarian Reserve

    DHEA & Testosterone Levels

    Hello, I am wondering what you thoughts were on my situation. I just turned 39 and I have “lean” pcos. I have one living child conceived 6 years ago through medicated timed intercourse. Since then I have had a few… — Stephanie W.

    Dr. Geoffrey Sher answered

    Here is an article I wrote on PCOS an IVF: Polycystic ovary syndrome (PCOS) is a common hormonal system disorder among women affecting between 5% and 10% of women of reproductive age worldwide. Women with PCOS may have enlarged ovaries that contain small collections of fluid — called…

  15. Hormones & Ovulation

    Infertility/Recurrent loss

    Hello Dr. Sher, Thank you for taking the time to answer my questions. I have 1 daughter (age 16) then loss my son at 23 weeks gestation 2 years later, had 3 ectopic pregnancies and 4 chemical pregnancies. I've had… — Janeé B.

    Dr. Geoffrey Sher answered

    Your underlying PCOS does not explain the losses (chemical or ectopic). You likely have an underlying secondary implantation dysfunction which could be an autoimmune and/or alloimmune, immunologic implantation dysfunction (IID). The presentation suggests that it possibly is more likely the latter. Endometriosis is associated with an IID in…

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