Dr. Geoffrey Sher

Reno Gazette Journal

Cyclical Estrogen Therapy Prior to Embryo Transfer, in Post-Menopausal Women and those with Prolonged Hypothalamic Amenorrhea, Can Reduce the Chance of Failed IVF and Miscarriage

 
An absence of menstruation (amenorrhea) in reproductive age women is
usually due to an absence of ovulation (anovulation). If this becomes
prolonged, then these women are at risk for the ill effects associated
from chronically low estrogen levels (hypoestrogenemia).  
Specifically, the women at risk for this would be those experiencing
premature ovarian failure (early menopause) or hypothalamic
amenorrhea. Whatever the cause, hypoestrogenemia will eventually lead
to a shrinkin…

Cyclical Estrogen Therapy Prior to Embryo Transfer, in Post-Menopausal Women and those with Prolonged Hypothalamic Amenorrhea, Can Reduce the Chance of Failed IVF and Miscarriage Read More »

The Sacramento Bee

The Role of IVF in the Management of Infertility Caused by Pelvic Inflammation

Pelvic Inflammatory Disease (PID) refers to inflammation of pelvic
structures including the uterus, fallopian tubes
[/blog/role-ivf-cases-tubal-damage/], ovaries, bowel, and the smooth
membrane that lines the surface of the pelvic cavity (the peritoneum).
PID
[/blog/pelvic-inflammatory-disease-pid-tubal-damage-hydrosalpinx-preparing-ivf/]
follows inf…

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Case Report: Can Intralipid/Steroid Therapy be Used Without Undergoing IVF?

_Question posed by by Patient X: _ Can oral steroids (prednisone) and
IL therapy be done without IVF? I have had 2 failed IUI’s 2 years
ago, but I do not like taking ovulation stimulating hormones. I have
endometriosis (not sure of what stage), am not currently working with
an RE, and have been TTC for 6 years. I have a higher than normal for
TTC TSH level (3.5-4), am 34Y/O, totally normal and regular periods
with ovulation almost every month, and husband checks out with good
numbe…

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The Number of Embryos/Blastocysts Transferred & PGT: Effect on IVF Outcome:

A “competent” embryo is one that is chromosomally, genetically and
metabolically capable of propagating a viable conceptus in-utero. Such
an embryo will have the same chance of resulting in a baby whether it
is transferred cleaved( on day 2,3,4) or as a blastocyst (day 5 or 6),
post-fertilization. Currently, we have no ability to reliably assess
the genetic and metabolic integrity of an embryo. The only tools we
currently have to rely on are: a) the embryo’s microscopic
appearance …

The Number of Embryos/Blastocysts Transferred & PGT: Effect on IVF Outcome: Read More »

Case Report: Egg Donation-Mother Uses her Daughter’s Eggs to conceive

The case involves D.R, a recently remarried, premenopausal woman in
her late 40’s, who had a daughter (N.R.) some 33Y ago, in a prior
marriage. D.R. inquired whether I would be willing to do IVF on her
daughter, fertilize the eggs with her husband’s sperm and then
transfer the embryos to her (DR’s) uterus. Needless to say, it was
recognized that if successful, and D.R. were to give birth to a baby
born from NR’s eggs, she would be giving birth to her own genetic
grandchild who wo…

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Case Report: The Diagnosis of “Unexplained” Recurrent IVF-Failure is Sometimes a Cop-out

Ingrid (37y) and Jesse 41y had been trying to conceive for 6 years.
The couple was “thoroughly tested” and had been “labeled” as
having _“unexplained infertility”._ Ingrid had patent fallopian
tubes, a normal (regular) uterine cavity, was experiencing regular and
normal menstrual cycles and her ovulation was found to be normal with
adequate supporting hormonal environment. Jesse had normal sperm
parameters and had in fact initiated a pregnancy in a previous
relationship,…

Case Report: The Diagnosis of “Unexplained” Recurrent IVF-Failure is Sometimes a Cop-out Read More »

Case Report: IVF in a 32y old with Premature-Menopause Following Cancer Chemotherapy.

Malia (33y) and her husband, Paul (41y), presented to me a few months
back. with 3 years of primary infertility (she had never conceived in
the past). Paul had initiated 3 pregnancies in a previous marriage and
by all tested parameters, was fertile. Malia on the other hand, was
menopausal with absent ovulation and menstruation. She had been
diagnosed with and treated for Leukemia 12 years prior and had been in
full remission for the last decade. However, her chemotherapy had
caused progr…

Case Report: IVF in a 32y old with Premature-Menopause Following Cancer Chemotherapy. Read More »

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