Hello Dr Sher, I am a scientist and as I often do i studied all mechanisms of action of IVF drugs. I have done natural start cycles but recently had leading follicles. AMH of 1.33 40 years old 6-9 afc but past two months afc got to 20. My IVF doctor for next cycle is suggesting estrogen patches 5 days before period and 3 shots of cetrotide 3 days before cycle. My question is – is this too suppressive? Often LH surges day of period guarantees follicle recruitment and cetrotide will completely suppress that. I have been oversuppressed by bcp and I have used estrace before with not too different results than natural start anyways. I’m deadly afraid of oversuppression especially now that my afc seems to have improved (changed lifestyle last 6 months). The protocol of stim after priming would be typical antagonist with clomid menopur follitism and dexamethasone. Let me know your thoughts on this strange priming protocol thanks!