Dr. Geoffrey Sher

Embryo transfer (ET) is undoubtedly a rate limiting factor in IVF.
Unquestionably, the IVF doctor’s expertise in performing ET as one
of the most important factors that will determine IVF outcome. It
takes confidence, dexterity, skill, gentility and above all,
experience to do a good transfer. This having been said, of all the
procedures in IVF this is the most difficult to teach. It is a true
“art” and there is little doubt that many women will fail to
conceive following IVF simpl…

It is only through propagation of our biological offspring that we as
humans can leave a lasting legacy of our existence. Perhaps this
explains why the desire to have children is a basic human instincts
and why an inability to achieve this goal (infertility) often leads to
considerable psychological and social difficulties. Infertility evokes
a strong sense of failure, loss and helplessness leading to one of
life’s most distressing crises. Seven out of ten children and young
adults wit…

The conventional way of conducting IVF treatment is to provide
patients with opportunity to undergo treatment any time they are ready
to do so. But such delivery of services in fact often falls short of
affording access to the most efficient and best quality of treatment
because it fails to allow much needed opportunities for clinical and
laboratory staff to take much needed breaks in order to implement
optimal quality control and to recover from the pressure resulting
from uninterrupted…

It is hard for me to believe that more than three decades have flown
by since I first introduced intrauterine insemination into the
clinical arena (Journal of Fertility & Sterility, April, 1984). At
that time and for more than 2 decades thereafter, I held the strong
belief that IUI would provide a less expensive, safe and equally
successful alternative to  IVF in cases where the woman had at least
one patent Fallopian tube… How wrong I was! In my defense however,
let me say that in th…

Unless tests for immunologic implantation dysfunction (IID) i
[https://blog.drgeoffreysherivf.com/endometriosis-immunologic-implantation-dysfunction-iid-ivf/]mmunologic
implantation dysfunction [/blog/endometriosis-and-infertility-sfs/]are
performed correctly and conducted by a one of the few reliable
reproductive immunology reference laboratory in the United States,
treatment will likely be unsuccessful. . In this regard…

All multiple pregnancies pose a risk to both mother and offspring.
Pregnancy induced maternal complications such as miscarriage,
pre-eclampsia, antepartum and post-partum hemorrhage become
progressively more prevalent the higher the multiple gestation. For
the babies, it is an escalating risk of premature birth and
intrauterine growth retardation that places the offspring at risk.

Ovarian hyperstimulation syndrome (OHSS) is a life-endangering
condition that occurs following ovarian stimulation
[/blog/ovarian-stimulation-for-women-with-diminished-ovarian-reserve-dor-and-in-older-women-undergoing-ivf/]
for the treatment of infertility. It occurs due to overstimulation of
the ovaries with the development of numerous follicles in susceptible
women. S…

The numerical chromosomal configuration of a cell is referred to as
its karyotype or ploidy. A cell with an irregular chromosome number is
referred to as aneuploid while one with a normal karyotype, as
euploid. It is predominantly (but not exclusively) the chromosomal
configuration of the embryo that determines its subsequent ability,
upon reaching a receptive uterine environment, to propagate a normal
pregnancy, also referred to as its “competence.” A “euploid”
(compet…