Dr. Geoffrey Sher

Male factor problems as a contributing cause of infertility are very
common. Male infertility is reported as a factor in 30-50% of
infertility cases. In fact, many fertility specialists will recommend
a semen analysis as one of the very first tests that should be done.
It is relatively simple, inexpensive and yields much information. The
two main causes of male factor infertility can be divided into either
problems in manufacturing sperm or problems in getting sperm outside
of the body (…

The objective with In Vitro Fertilization is to consistently transfer
competent embryos into a receptive uterine environment. This requires
a very individualized and meticulous approach to evaluating and
addressing those factors that can influence IVF outcome
[/blog/fundamental-requirements-achieving-optimal-ivf-success/]: All
patients/couples should learn what they can reasonably expect before
committ…

I have all too often heard it said that medical providers knowingly
place unsuspecting infertile women at risk of developing cancer
through the fertility injectable drugs and treatment they administer
and that we knowingly place patients at risk by understating medical
risks associated with the use of fertility treatments
[/blog/ivf-pregnancies-bear-greater-risk/]. To me this is both
offensive and untrue. It is true that the indiscrim…

Implantation dysfunction [/blog/endometriosis-and-ivf/] is
unfortunately often overlooked as an important cause of IVF failure.
In the pursuit of optimizing outcome with IVF, the clinician has a
profound responsibility to meticulously assess and address this
important issue if IVF success is to be optimized. This is especially
relevant in cases of “unexplained …

With cervical Incompetence (CI) the cervix starts to shorten (efface)
and dilate too early in the pregnancy giving rise to late (2nd
trimester) miscarriage or premature birth. It can occur with first
pregnancies (“Primary Cervical Incompetence”) or after a prior
pregnancy (“Secondary Cervical Incompetence”). CI often occurs in
women who give a history of cervical insufficiency in one or more
prior pregnancies; late miscarriages or premature deliveries of
unknown cause; cervical i…

About a decade ago, I, along with my associate, Levent Keskintepe PhD
were the first to introduce full chromosome Preimplantation Genetic
Testing (PGT)
[/blog/preimplantation-genetic-sampling-pgs-using-next-generation-gene-sequencing-ngs-method-of-choice/]
into the IVF clinical realm to try and identify euploid embryos whose
cells contained the required 46 chromosomes…

CASE REPORT: **For the purposes of anonymity, I will be referring to
the patient as RL throughout this blog.** RL, a 31-year-old woman,
presented with a 7 year history of inability to conceive, in spite of
2 prior fresh and 1 frozen IVF attempts
[/blog/frozen-embryo-transfer-fet-versus-fresh-et-make-decision/],
where a total of six

Hi Dr Sher, I’m 42 years of age. Until very recently, I knew nothing
about IVF, and I now find myself in a scramble to optimize my chances
with it. Despite a lifelong dream of having a healthy baby and happy
family, it has taken me this long to find a great man/dad I can
believe in for my unborn kids, so prior, I always used protection and
never tried to get pregnant. Since my mom got pregnant naturally at
40, I grew up thinking that was normal-or at least normal for my
family. And, I …

Following ovulation, what remains of the ruptured follicle transforms
itself into a structure called the Corpus Luteum (CL) which produces
progesterone. The purpose of progesterone is to prepare the uterus to
accept and support an early pregnancy until it is able to sustain
itself at around 8-10 weeks of gestation.
The life span of the CL is predetermined to be 12-13 days, unless
rescued by a signal from the early pregnancy. If no pregnancy occurs,
the CL …