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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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180 answers

IVF Failure & Pregnancy Loss

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Egg Health & Ovarian Reserve May 9, 2024

5 failed IVF rounds – Low AMH –

Dear Dr Sher Geoffrey, I have been through 5 failed IVF rounds. Most of the time my eggs are degenerative, empty or abnormal. I have a 2 year old daughter, concieved naturally, only in 2 months of trying. Now I… — Mary V.

Dr. Geoffrey Sher answered

Hi Sherella; I really think I can help you sort all this out.m However, to do so we would need to consult. I invite you to call my assistant, Patti Converse at 702-53302691 and set up an online consultation with me. ADDRESSING DIMINISHING OVARIAN RESERVE (DOR) IN IVF…
Immunology & Implantation May 4, 2024

RPL and hydroxychloroquine

Hi Dr Sher, I've been getting mixed advice from consultants and I'm hoping you can help. I'm 40years old and have one child, conceived with no issues, and have had a number of chemical pregnancy losses. I'm conceiving very easily,… — Bronagh M.

Dr. Geoffrey Sher answered

Thanks for the inquiry. I think I can help here. Might I suggest that you contact my assistant Patti Converse at 702-533-2691 and set up an online consultation with me to discuss in depth. Geoff Sher When it comes to reproduction, humans face challenges compared to other mammals.…
Embryos & Genetic Testing Apr 23, 2024

Failed FET w/ Autoimmune disorder

Hello Dr. Sher, I listen to your podcast with Dr. Aimee Eyvazzadeh and I wanted to engage with you before going into another FET w/egg donor my questions to you: 5 year IVF Journey/History: * Zero pregnancy * 2 Aneuploid… — Rosalyn G.

Dr. Geoffrey Sher answered

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Immunology & Implantation Apr 10, 2024

Secondary Recurrent Pregnancy Loss and possible IID

Hi Dr Sher, I am 40 years old and have suffered with a number of early pregnancy losses in the past year, all conceived naturally. I have a 3 year old son who was conceived easily with no issues during… — Bronagh M.

Dr. Geoffrey Sher answered

When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
Infertility Basics Apr 10, 2024

RPL, Secondary Infertility

Hello Dr. Sher, I am experiencing my 4th biochemical pregnancy in less than 2 years. I am 45 years old with 8 previous live births. My youngest son turned 2 years old in January. I recently acquired Day 3 labs… — Faith R.

Dr. Geoffrey Sher answered

I am attaching an article I wrote on RPL but I would like to preface this by saying that at 45y of age, and especially with concomitant DOR, the large majority of your eggs will be aneuploid and resulting embryos too. Such embryos, if they implant will be…
IVF Failure & Pregnancy Loss Apr 9, 2024

Yulissa

Aserca de mi tratamiento — Yulissa A.

Dr. Geoffrey Sher answered

Please re-post in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility…
Embryos & Genetic Testing Apr 9, 2024

Recurrent biochemical & Ectopic

Hi Dr Sher, Could you please try and answer what could be causing my issue and possible solution. I am 38 (husband 40) and we are married for 13 years; trying for a child since 10 years. I never had… — Indira V.

Dr. Geoffrey Sher answered

When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
IVF Failure & Pregnancy Loss Apr 1, 2024

I need help with ivf

Hi . I try ivf I don’t get pregnant :( I want baby but I can’t pay a lot money I don’t have :( I need help plz — Ikhlas D.

Dr. Geoffrey Sher answered

If you've undergone in vitro fertilization (IVF) and didn't achieve a successful pregnancy, you may be wondering why. It's important to know that IVF outcomes can be unpredictable, but there are factors that can affect your chances. Let's explore some common reasons for IVF failure in simpler terms.…
IVF Failure & Pregnancy Loss Mar 25, 2024

Female miscarriages

Pleaze call [phone number removed] — Charlotte L.

Dr. Geoffrey Sher answered

I suggest you call my assistant, Patti Converse at 702-533-2691 and set up an online consultation with me to discuss. Geoff Sher When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births,…
Embryos & Genetic Testing Mar 25, 2024

IVF Failure/ embryo issue

Hello Dr. Sher, I just watched a video of your interview with Dr. Aimee regarding RIF. I am age 36 with 5 failed to implant IUI's and 2 IVF retrievals with donor sperm. Prior to now I never tried to… — Michelle D.

Dr. Geoffrey Sher answered

ADDRESSING DIMINISHING OVARIAN RESERVE (DOR) IN IVF Understanding the impact of ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols…
Immunology & Implantation Mar 21, 2024

Recurrent miscarriage

Dr sher In the past 2 years I have had 2 mmc one at 6 weeks and one at 9 weeks. The products were tested of the 9 week one it was genetically normal. After that I have had 3… — Tara B.

Dr. Geoffrey Sher answered

Having done the tests you describe has no real merit if they were not done at one of about 4 Reproductive Immunology Laboratories in Th US that can do these tests with optimal specificity and sensitivity. We need to talk! I invite you to contact my assistant, Patti…
IVF Failure & Pregnancy Loss Mar 19, 2024

Infertility

Can letrozol and omega3 take together during period — Bamikole O.

Dr. Geoffrey Sher answered

Yes! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) ;…
Embryos & Genetic Testing Mar 15, 2024

Recurrent Implantation Failure

Hello Dr. Sher at my current clinic I have gone through 4 transfers with PGT-A normal embryos. My first transfer resulted in a chemical pregnancy, but the following transfers did not implant at all. The tests I have done are… — Ashley P.

Dr. Geoffrey Sher answered

In my opinion this is almost certainly an implantation dysfunction. Bear in mind that in 30% of cases, endometriosis is associated with an immunologic implantation dysfunction. Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or…
IVF Failure & Pregnancy Loss Mar 4, 2024

Next Steps

aI am a 36 y.o. female with PCOS. I have had 2 miscarriages at 6 weeks (1 from an IVF transfer recently and 1 from letrozole round several years ago) , and 2 failed IVF transfers that failed to implant.… — Christy L.

Dr. Geoffrey Sher answered

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
IVF Failure & Pregnancy Loss Feb 25, 2024

Recurrent Implantation Failure

Hello! I am a 24 y.o. female, Gravida 0, AMH 0.2-0.8, four failed IUI’s, and now 4 failed transfers with 5 embryos never implanting. I’ve done two ERA’s (both postreceptive at 96 and 72 hours) but we’ve ignored these results… — Delaney D.

Dr. Geoffrey Sher answered

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

180 answers

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