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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Answers from our doctors

Search 1,017 questions patients have already asked, or narrow them by topic.

  1. Embryos & Genetic Testing

    Failed FET

    Hi Dr. Sher, You did my egg retrieval 3 years ago, and we welcomed our beautiful daughter 2 years ago. We just did another transfer of 1 pgt embryo for a baby boy, and it failed. We only have 1… — Megan L.

    Dr. Geoffrey Sher answered

    We should talk. Please call my assistant, Patti (702-533-2691) and set up an online consultation to discuss. Geoff Sher

  2. Embryos & Genetic Testing

    PGT-A results

    Dear Dr Sher, I have listened with interest to your interviews on The Egg Whisperer and I hope you won’t mind my reaching out. I am a 46 year old woman from London, UK. I began IVF treatment with my… — Belle E.

    Dr. Geoffrey Sher answered

    There is no point in holding on to a "complex aneuploid embryo". You should discard it , in my opinion. There can be a very rapid decline in AFC at your age . This is because of inevitable decline in ovarian reserve and in egg quality. If you…

  3. Embryos & Genetic Testing

    My embryo segmental abnormal

    I worked with you about 3 years ago. Thank you for helping us to our dream daughter. We are forever grateful. My question is about another embryo I would like to transfer . This is how it’s labeled, 46,XX,del(4)(q22). In… — Haley P.

    Dr. Geoffrey Sher answered

    Wonderful hearing from you...You made my day! I invite you to call 702-533-2691 and ask my assistant, Patti Converse, to set up an online consultation with me to discuss. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books…

  4. Embryos & Genetic Testing

    PGT-A

    Dear Dr Sher, I have listened with interest to your interviews on The Egg Whisperer and I hope you won’t mind my reaching out. I am a 46 year old woman from London, UK. I began IVF treatment with my… — Belle E.

    Dr. Geoffrey Sher answered

    If the embryo is aneuploid, there is no merit in keeping it. Frankly, trying with own eggs at 45y with such severely diminished ovarian reserve is ill-advised. You need an egg donor. ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF Understanding the impact of age and…

  5. Embryos & Genetic Testing

    FET for women over 45

    Hello! I wanted to see if your fertility office has a maternal age limit to transfer frozen embryos? I am 49 and have two frozen embryos that were frozen when I was 36. My current fertility clinic will not continue… — Barb J.

    Dr. Geoffrey Sher answered

    Absolutely no such age limit! Two decades ago, when women went through IVF (in vitro fertilization), they usually had their embryos put in the uterus right after the eggs were collected in the same cycle (known as "Fresh" Embryo Transfer). Freezing embryos at that time was risky, with…

  6. Embryos & Genetic Testing

    AMA and RPL (Secondary Infertility) – Chemical after First FET

    I just found out my first FET with a PGT-A tested 6AA embryo is ending in a chemical. I'm 35 with 2 known autoimmune issues (vitiligo and Reynaud's) and a history of RPL (2 miscarriages, at 7 and 8 weeks).… — Jillian B.

    Dr. Geoffrey Sher answered

    When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…

  7. Embryos & Genetic Testing

    Baby

    Good day I am looking for info. I am a 36 year old single female from NY. I would love to adopt a boy embrio, black hair and blue eyes, white. I am not able to have kids of my… — Jorja P.

    Dr. Geoffrey Sher answered

    I suggest you call Patti Converse (my assistant) and set up an online consultation with me to review your case and make suggestions. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In…

  8. Egg Health & Ovarian Reserve

    Repeat implantation failure

    Hi Dr. Sher, I come from Denmark and here we can't screen our embryos - so we transfer untested. I have had all initial testing done in August last year before starting my egg retrievals and all my tests were… — Julie R.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

  9. Embryos & Genetic Testing

    Important

    Do you help a women get pregnant with twin babies if she’s 29 years old? — Nathan K.

    Dr. Geoffrey Sher answered

    There is no guarantee that if you transfer >1 embryo you will get a multiple pregnancy. I suggest you call Patti Converse (my assistant) and set up an online consultation with me to discuss. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are…

  10. Embryos & Genetic Testing

    Mosaic 20p embrio

    Dear Dr. Sher, We have only one embrio with following NGS data: seq[GRCh37] (20p13p11.21)x1[0.27],(X,Y)x1 Would you please tell, how much are the risks in the case of transfer? Thank you — Alex B.

    Dr. Geoffrey Sher answered

    In my opinion, it is worth transferring BUT ...if/once pregnant, you should do a CVS or amniocentesis to assess the pregnancy. Decoding Embryo Mosaicism: Navigating the Complex Path to Healthy Births\ Human embryo development is a marvel of intricate processes, including reprogramming, sequential cleavage divisions, mitotic chromosome segregation,…

  11. Embryos & Genetic Testing

    Two failed IVF with healthy embryos

    Hi! I recently had 3 failed iuis and two failed transfers with seemly healthy embryos (BA BB) These eggs were from when I froze them at age 34. I am now 40 and have no embryos left. I have had… — Carolyn S.

    Dr. Geoffrey Sher answered

    IVF FAILURE WITH “NORMAL” EMBRYOS: EXAMINING AND ADDRESSING ANATOMICAL AND IMMUNOLOGIC CAUSES. Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as…

  12. Embryos & Genetic Testing

    Gender Selection Options

    Hello, What options are available that allow for gender selection? Thanks! Michelle B — Michelle B.

    Dr. Geoffrey Sher answered

    Couples have for centuries sought to influence the gender of their offspring. More than seven centuries ago the ancient Chinese developed a birth calendar said to be able to predict gender on the basis of when conception occurred. Later, the ancient Greeks suggested that by lying on her…

  13. Embryos & Genetic Testing

    Frozen embryo transfer add on

    Hello Dr. Sher, Hope you are doing well.. 1. What is your view about hcg booster shots between ovulation induction and transfer for modified natural transfer? Does it have positive effect on endometrium before transfer? If yes what will be… — Sreevidhya V.

    Dr. Geoffrey Sher answered

    What is your view about hcg booster shots between ovulation induction and transfer for modified natural transfer? Does it have positive effect on endometrium before transfer? If yes what will be the ideal protocol and dose for hcg booster? A: I do not advocate this! 2. What is…

  14. Embryos & Genetic Testing

    2nd opinion

    Hi. Is it possible to get a second opinion on my IVF process? I'm located in Philadelphia and won't be getting IVF at your clinic. I just wanted to find out Dr. Sher's opinion about my IVF protocols and what… — Kseniya F.

    Dr. Geoffrey Sher answered

    Please call Patti at 702-533-2691 or email her at concierge@sherivf.com and set up an online consultation with me. Geoff Sher EGG/ EMBRYO QUALITY IN IVF & HOW SELECTION OF THE IDEAL PROTOCOL FOR OVARIAN STIMULATION INFLUENCES EGG/EMBRYO QUALITY AND OUTCOME. The journey of in vitro fertilization can be…

  15. Embryos & Genetic Testing

    Transfer of monosomy embryo

    Hi, We have a PGT-tested monosomy 19 blastocyst that is presently frozen. Mosaicism was not detected. We are no longer doing retrievals. The lab that conducted our PGT-A testing said Monosomy19 is in the group of genetically abnormal embryos that… — Mike R.

    Dr. Geoffrey Sher answered

    I would agree! I would transfer the embryo, provided you undergo CVS or amniocentesis during pregnancy and are willing to consider pregnancy termination should there be a chromosomal fetal abnormality diagnosed. Geoff Sher

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