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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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231 answers

Embryos & Genetic Testing

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Embryos & Genetic Testing Jan 11, 2025

Eight losses

Hello, my name is Vikki Carpenter. I am 40 years old and started IVF last year. I have one IVF failure (chemical), and 7 other chemical pregnancies before IVF. The pattern is virtually the same: I get pregnant and within… — Vikki C.

Dr. Geoffrey Sher answered

UNDERSTANDING RECURRENT PREGNANCY LOSS ( RPL): CAUSES AND SOLUTIONS. When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending…
Embryos & Genetic Testing Jan 11, 2025

News Reporter

hi, would love to talk to you about PGT testing for a story. — Amy K.

Dr. Geoffrey Sher answered

Please contact my assistant Patti (concierge@sherIVF.com. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) ; https://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf Recurrent Pregnancy Loss and…
Embryos & Genetic Testing Jan 11, 2025

Recurrent pregancy loss and ivf failures cause

I had 3 natural pregnancies that ended up in miscarriages and 3 embryos pgt tested implanted that failed. I want to know the cause — Joyce M.

Dr. Geoffrey Sher answered

UNDERSTANDING RECURRENT PREGNANCY LOSS ( RPL): CAUSES AND SOLUTIONS. When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending…
Embryos & Genetic Testing Nov 27, 2024

Embryo Transfer

Is it normal take 10mg Prednisolone 5 days before transfer and 5 Progynova a day? If so, do you have any suggested reasons why this might be the case ? Also how do you improve blood circulation prior to transfer?… — Meshelley S.

Dr. Geoffrey Sher answered

Respectfully, I do not uses such an approach! Geoff Sher
Egg Health & Ovarian Reserve Nov 24, 2024

IVF

I am 28 and my husband is 27. My husband was diagnosed with male factor infertility 1 year ago (low count, low motility). Our first IVF round produced 17 eggs, 14 mature, 14 fertilized and 6 untested fair quality blasts.… — Payton D.

Dr. Geoffrey Sher answered

I do not think the reason for your failed cycles was due to the male factor. It sounds more like an implantation dysfunction. We should connect online and discuss this in depth. I think I can help. Please call my assistant, Patti Converse at 702-533-2691 and set up…
Embryos & Genetic Testing Nov 22, 2024

Opinion on french MatriceLab test

Dear Dr. Sher, Thank you for the detailed article on immunological issues of embryo implantation failures. I'm writing to you as a fertility patient in France. After a certain number of blastocysts transfered with a single implantation and early miscarriage,… — Manon G.

Dr. Geoffrey Sher answered

I aplaud any research that serves to uncover the immunologic basis for implantation dysfunction. Endometrial local immunity is likely an important parameter that influences implantation and the the prognosis of pregnancy.. Diagnosis of an endometrial immune dysregulation . It seeks to assess embryo-endometrial interaction and focuses on several…
Embryos & Genetic Testing Nov 14, 2024

Recurrent implantation failures

Dear Dr. Sher, Myself and husband are both 38 yrs old started our fertility journey at the age of 32 yrs so trying to conceive for 6 yrs now. We started with ovulation induction, had an ectopic treated with methotrexate.… — Remy A.

Dr. Geoffrey Sher answered

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Embryos & Genetic Testing Nov 8, 2024

Vitrification of embryos

Dear Dr. Sher, do you have experience with the freeze of day 4 embryos (morulas)? My clinic is suggesting that we freeze all remaining embryos on day 4 after transfer on same day, because day 5 is a Sunday and… — Cathryn L.

Dr. Geoffrey Sher answered

Frankly, I prefer to go to blastocyst just to have more confidence in embryo viability, however, transferring as morula isa acceptable. Geoff Sher Geoff Sher
Egg Health & Ovarian Reserve Oct 30, 2024

Changes to a 4th cycle

I’m at a bit of a loss. Having ICSI for secondary infertility (1st child conceived naturally age 29) and just midway through my 3rd cycle. I have paid up for a 4th cycle already so I’m keen to get some… — Amy E.

Dr. Geoffrey Sher answered

WE would need to discuss this complex matter. I suggest you call my assistant, Patti Converse (702-533-2691 and set up an online consultation with me. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my…
Embryos & Genetic Testing Oct 30, 2024

Haploid

What could cause a day 7 BB blastocyst that was fertilized via ICSI to be haploid (PGT-A results)? — Addison J.

Dr. Geoffrey Sher answered

It is likely "incompetent". Geoff Sher
Egg Health & Ovarian Reserve Oct 28, 2024

Advice for last IVF round

Dear Dr. Sher: Thank you for hosting this forum. I am just shy of 41 with social infertility and have had two failed IVF cycles. The first used an antagonist protocol at 300 IU gonadotropin and resulted in one whole… — Claire C.

Dr. Geoffrey Sher answered

Please read what follows and thereupon, might I suggest that we talk . Please call my assistant. Patti at 702-533-2691 and set up an online consultation with me to discuss. The journey of in vitro fertilization can be a rollercoaster of emotions for many patients. Often times they…
Embryos & Genetic Testing Oct 16, 2024

FET canceled due to a yeast infection (vaginal candidiasis)

My fresh embryo transfer was canceled two days before the procedure due to a yeast infection (vaginal candidiasis), and I’m wondering why this infection may have occurred. I haven’t had sexual intercourse or done anything specific that I believe could… — Hannah A.

Dr. Geoffrey Sher answered

In my opinion there is no reason to cancel FET because of a yeast infection. Geoff Sher
Egg Health & Ovarian Reserve Sep 30, 2024

Bad quality eggs

Dear Dr. Sher. I am out of options i feel. Unknown fertility problem, endometriosis. I am now 30 years old. For the last 5 years: 5 IVF/ICSI cycles, 65 mature eggs, 30 fertilized, 0 good blastocyst, only poor quality, nothing… — Maggy M.

Dr. Geoffrey Sher answered

Embarking on the journey of IVF often raises questions about the likelihood of success and the quality of embryos. While it’s challenging to predict outcomes due to various factors, there’s hope and information to guide you. Firstly, the key to fertilization potential lies in the chromosomal integrity of…
Egg Health & Ovarian Reserve Sep 30, 2024

It’s over

Dear Dr. Sher, I am 43 years old, and in the last 2 years: 6 cycles, 100 follicles, 90 oocytes collected, 60 oocytes matured, 50 embryos, 10 blastocytes, 1 euploid. One abortion (prior to ivf), two failed transfers (the euploid… — Anne C.

Dr. Geoffrey Sher answered

I think we should talk first before you make that determination definitively. If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or email her at concierge@sherivf.com\ Geoff Sher ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF…
Embryos & Genetic Testing Sep 4, 2024

Treatment for immune issues and euploid RPL

Hello, I am a 32 y/o in Canada with history of 3 euploid miscarriages. First pregnancy embryo stopped growing 6.5 weeks, second pregnancy was a MMC of a blighted ovum, third pregnancy mono/mono twins resulted from a single embryo, both… — Anastasia S.

Dr. Geoffrey Sher answered

Respectfully, your immunologic implantation dysfunction is likely due to an alloimmune cause and if so would require different treatment (see below and read the E-books presented below ). I suggest you call my assistant, Patti Converse and set up an online consultation with me to discuss your case…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

231 answers

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