Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

Search the answers our doctors have already given

Fill in the following information and we’ll get back to you.

Answers from our doctors

Search 1,017 questions patients have already asked, or narrow them by topic.

231 answers

Embryos & Genetic Testing

Clear all

Embryos & Genetic Testing Aug 28, 2025

Recurrent Failed implantation

H! Dr. Sher , I am honored to have a chance to ask you some questions about IVF . My husband and I just had a failed embryo transfer which was our 4th transfer with a euploid embryo and all… — Maria P.

Dr. Geoffrey Sher answered

Thank you for your communication. Below please find information that I feel confident will help explain the possible reasons for implantation dysfunction. Thereupon, if you would like to have a consultation with me to discuss your circumstances and potential remedies, please call or text my assistant, Patti Converse…
Embryos & Genetic Testing Aug 15, 2025

Repeat failed implantations

I have experienced one miscarriage and four failed implantations with untested embryos. In my recent IVF cycle, I obtained one PGT-A–tested 5AB euploid embryo. I also underwent a hysteroscopy with a uterine biopsy to investigate the failed implantations, and all… — Fab W.

Dr. Geoffrey Sher answered

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Embryos & Genetic Testing Aug 15, 2025

Second transfer

Hello!! I wanted to inquire about a possible timeline for a second embryo transfer. My daughter was born via c section 11/19/24. We have been trying to conceive since January of this year. When would be an appropriate time to… — Samantha L.

Dr. Drew Tortoriello answered

Any cycle would be fine! FROZEN EMBRYO TRANSFER : ONE PREFERRED APPROACH AT SFS. Two decades ago, when women went through IVF (in vitro fertilization), they usually had their embryos put in the uterus right after the eggs were collected in the same cycle (known as "Fresh" Embryo…
Embryos & Genetic Testing Jun 23, 2025

Dup(13)(q21.1-qter)[mos]

DI have a high level mosaic Dup(13)(q21.1-qter)[mos] tested by Cooper. My doctor had incureged me to transfer but genetic councilor seemed concerned. What do you think? — Veselina M.

Dr. Geoffrey Sher answered

I agree with your doctor unless there is a pressing reason to 1st do another cycle using a modified/improved protocol for ovarian stimulation to try and access more euploid embryos for use. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY…
Embryos & Genetic Testing Jun 23, 2025

Testing

I have a history of-two failed FET Embryos were not tested Embryos were not tested at 37 years old. I did two more rounds of IVF and I have now 7 euploids with CCRM I also did a lap to… — Michelle F.

Dr. Geoffrey Sher answered

They are wrong with regard to the Receptiva test. It is very helpful in diagnosing silent endometriosis which if present can be associated with an immunologic implantation dysfunction (IID) I am not a believer in Emma/Alice testing and ; The method of FET will not affect the risk…
Early Pregnancy & hCG Jun 11, 2025

First pregnancy scan after IVF with PGT

Hi, I've recently discovered I'm pregnant through IVF with an euploid embryo. I had my first beta HCG blood test at 12 days past transfer and this came back at 540 IU/L. I'm now waiting for my first scan in… — Mary D.

Dr. Geoffrey Sher answered

Congratulations!! I wish I could predict. Unfortunately you will need to wait for the US result! Good luck! Geoff Sher
Embryos & Genetic Testing Jun 5, 2025

Blighted Ovum

I just had my first FET, and it resulted in a blighted ovum. I am 35 years old with 5 PGT abnormal eggs. We will try again in a few months. But in the meantime, is there anything I should… — Kate S.

Dr. Geoffrey Sher answered

I would need much more information to provide an authoritative opinion. Feel free to contact my assistant, Patti (concierge@sherivf.com to set up an online consultation with me. to discuss. Geoffrey Sher MD ADDITIONAL INFORMATION: Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY…
Embryos & Genetic Testing May 29, 2025

Slow frozen

Dear Dr Sher! We have a patient who has 6 slow-frozen embryos. She wants to donated them to another family. WE attempted to find a recipient family for her; however, most fertility clinics do not want to accept slow frozen… — Alena W.

Dr. Geoffrey Sher answered

If they were frozen on day-3...indeed you could do that. But if they were frozen as blastocysts, the thaw-biopsy-refreeze can damage the embryos. Good luck Geoff Sher ADDITIONAL INFORMATION: Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your…
Early Pregnancy & hCG Apr 27, 2025

To know much about my IVF journey

Thank you for receive me, what if my LH level is higher (15,45 mIU/ml on Day 3 of menstrual cycle — Paola U.

Dr. Geoffrey Sher answered

I would need much more information. If you would like to discuss your case with me , email my assistant (702-533-2691 and set up an online consultation with me,
Early Pregnancy & hCG Apr 1, 2025

FET

Hi Dr Sher I’m 38 y/o and and going through fertility treatment using donor sperm. I have just had an unsuccessful fresh ICSI embryo transfer (6 eggs retrieved, 6 fertilised, grade A embryo transferred, 3 embryos frozen grades B B… — Liz D.

Dr. Geoffrey Sher answered

I Thank you for sharing your IVF treatment details. From what you’ve described, you are 38 years old and have recently undergone your second IVF cycle, during which three cleaved embryos of reasonable quality were transferred, but unfortunately, conception did not occur. In your first cycle, a single…
Embryos & Genetic Testing Mar 3, 2025

RIF

We have had 1 successful implantation which ended in a miscarriage at 8 weeks. 1 chemical pregnancy and 4 failed implantation - 3 of which were with euploid embryos. Husband has poor SA (varicocele) and I have been diagnosed with… — Z M.

Dr. Geoffrey Sher answered

Respectfully, Elevated DFI does not negatively affect implantation. What you are experiencing is likely an implantation dysfunction which could be "immunologic" in origin and linked to endometriosis....see below. I suggest you contact my assistant, Patti Converse (concierge@sherivf.com and ask her to set up with an online consultation with…
Embryos & Genetic Testing Feb 23, 2025

RPL

I am a 42 year old women undergoing IVF treatment. I had a very successful egg retrieval (13 fertilized eggs, 9 blastocyst, after PGT-A testing: 3 euploid embryos and 1 low mosaic). We transfered our 3rd euploid embryo 2 weeks… — Lindsey M.

Dr. Geoffrey Sher answered

At 42y, IUI is definitely not the answer..please read below and thereupon (if so inclined) contact my assistant, Patti Converse (concierge@sherivf.com) and have her set up an online consultation with me. IMPLANTATION DYSFUNCTION Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially…
Embryos & Genetic Testing Feb 11, 2025

Article; IVF: FACTORS AFFECTING EGG/EMBRYO “COMPETENCY” DURING CONTROLLED OVARIAN STIMULATION (COS)

Quick question- sperm and egg cells, don' t they contain 23 chromosomes only as they are germ cells (Haploid cells) , and not 2x 23 as mentioned in this article? — Theivanya U.

Dr. Geoffrey Sher answered

Both sperm and eggs start off with 46 chromosomes. Then during meiosis (reproductive maturational division, the divide their chromosomes in half to 23 (the haploid number). The fusion of the sperm and the egg thereupon reconstitutes the chromosomes in the embryo to 46(the diploid number). Geoff Sher Herewith…
Egg Health & Ovarian Reserve Jan 23, 2025

Fertility at 41

Hello Dr Sher, I am a physician G3P2 who has gone through 6 cycles of IVF for my 3rd child. (My elder two are 11 and 9 who were naturally conceived and delivered NSVD). I have done luteal phase stimulation… — Heena P.

Dr. Geoffrey Sher answered

Thank you for reaching out to me. We should talk. I recommend that you contact my assistant, Patti Converse at concierge@sherivf.com and set up an online consultation with me to discuss. In the meanwhile, please see below. Geoff Sher ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN…
Clinic & Practice Jan 22, 2025

Consult with Dr. Sher

Recommendation regarding future IVF treatment- 41 y.o Female with DOR; multiple IVF cycles; embryos don't make it to blastocyst (only had 2 blastocysts) so far. — Neha K.

Dr. Geoffrey Sher answered

I agree! This requires an online consultation; I suggest you contact my assistant (Patti) and set this up with me. In the meanwhile, see below. Embarking on the journey of IVF often raises questions about the likelihood of success and the quality of embryos. While it’s challenging to…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

231 answers

Location

Follow Us