– Geoffrey Sher, MD
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IVF Failure & Pregnancy Loss
I had 4 chemical pregnancies what should I do — Selemawit Z.
Dr. Geoffrey Sher answered
When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
Embryos & Genetic Testing
Hello! My husband and I are doing IVF because he has ADPKD and we are trying to chose an embryo without that condition. We thankfully produced two healthy embryos (female) and one male without the ADPKD gene, negative segmental aneuploidy… — Loren S.
Dr. Geoffrey Sher answered
Human embryo development is a marvel of intricate processes, including reprogramming, sequential cleavage divisions, mitotic chromosome segregation, and embryonic genome activation. However, the journey towards a successful pregnancy is not without its challenges, as chromosomal abnormalities can occur during germ cell and preimplantation embryo development, leading to early…
IVF Failure & Pregnancy Loss
Quisiera tener una niña por un vidrio porque murió también mi esposo y mi esposo siempre querido una niña — Diana R.
Dr. Geoffrey Sher answered
Please repost in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility…
Embryos & Genetic Testing
Hi Dr. Sher, This has been a long journey. I did a fresh transfer at 38 (got 18 eggs, 5 to blast stage, but we did not test then), the fresh transfer resulted in a chemical. Had to take some… — Mary R.
Dr. Geoffrey Sher answered
On the face of it, this sounds very much like3 "implantation dysfunction). Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as…
Immunology & Implantation
Hi Dr. Sher, I listened to your podcast on RPL with Dr. Aimee on The Egg Whisperer. I'm 44F, I've had 2 FET's with 2 tested 4AA embryos. Both implanted, both failed to grow. I was on the kitchen sink… — Marissa D.
Dr. Geoffrey Sher answered
WE need to talk. Might I recommend that you call my assistant, Patti Converse at 702-533-2691 to set up an online consultation with me to discuss. Geoff Sher
IUI & Insemination
Hi Dr. Sher, I listened to the podcast on IUI with you and Dr. Aimee, the egg whisperer and I wanted to reach out to you in hopes of seeking your advice. I am a 34 year old who is… — Mallory F.
Dr. Geoffrey Sher answered
My bigger concern is that you might have an immunologic inmmplantation dysfunction and if so , IUI alone wont bve effective. This could explain your losses too. Between 2% and 5% of women in their childbearing years deal with hypothyroidism, a condition that affects women more than men.…
Infertility Basics
Quiero tener un bb — Neibe C.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
Cost & Insurance
Quiero saber el precio y los pasos a seguir — Alexa A.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) ; http://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf 2. Recurrent Pregnancy Loss and…
Uterine & Endometrial Health
Hi I was trying to do a treatment on another facility I have two frozen embryos. I want to know if I could do the Polypectomy at your office and do my check up on your office. I don’t know… — Tania L.
Dr. Geoffrey Sher answered
Absolutely this can be done. AND it is easy to relocate embryos to us. We do so all the time from all over the world. We in large part help facilitate this for you! G-d bless! Geoff Sher Herewith are online links to 2 E-books recently co-authored with…
Clinic & Practice
Hi Dr. Sher, My husband and I struggled with infertility and failed with IVF. Now we are pursuing embryo donation and we were matched with a couple whose embryos are stored at your clinic. We live in Rochester, NY and… — Mayumi K.
Dr. Geoffrey Sher answered
Absolutely, we often do this. It would probably take no more than 4-5 visits at our center over a 10 day period of time. all the time! More and more American women are exploring IVF treatments in their late 30s and in their 40s. This trend often stems…
Uterine & Endometrial Health
Hello:) I have an endometrioma cyst on my right ovary the drs want to do laparoscopy surgery but it runs the risk of getting good ovarian tissue and since I only have the right ovary I don’t want to do… — Lizeth C.
Dr. Geoffrey Sher answered
It is excellent alternative but unfortunately the medication needed to be injected into the cyst is no longer available. I wish I could help you! Geoff Sher Here is an article I wrote some time ago! • Effect of Advanced Endometriosis with Endometriotic cysts (Endometriomas) on IVF Outcome…
Embryos & Genetic Testing
Hello. My last retrieval only resulted in Day 7 embryos, which we sent for PGT testing. We have 1 euploid Day 7 and 1 Low level mosiac (segemental low level with deletion of of chromosome 15 on the q25.3 arm… — Sumi G.
Dr. Geoffrey Sher answered
Respectfully, in my experience day 7 blastocysts are not worthy of transfer. They rarely iuf ever, will propagate viable pregnancies. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro Fertilization…
Uterine & Endometrial Health
Hello Dr. Sher, I'm a 31 year old married G0 recently diagnosed with bilateral endometriomas: left 1.8x1.4 cm, right 9.8x8.4 cm. Currently on Lo Loestrin as treatment. I have never attempted to conceive but am very worried about future fertility… — Cotter C.
Dr. Geoffrey Sher answered
I no longer have access to a facility where this procedure can be performed and I do not know who to refer you to? Sorry! Geoff Sher
Infertility Basics
Hi there, I am a 41-year-old trying to decide whether to do an ERA and EMMA and ALICE tests ahead of my next donor egg transfer. I had two high-quality embryos transferred last time from a 20-year-old egg donor, but… — Lorna T.
Dr. Geoffrey Sher answered
• IVF FAILURE WITH “NORMAL” EMBRYOS: EXAMINING AND ADDRESSING ANATOMICAL AND IMMUNOLOGIC CAUSES. Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such…
Uterine & Endometrial Health
Dear Dr. Sher, Do you believe in the ERA? We did a modified natural mock cycle. Biopsy was performed at 158.5 hours after a took my trigger shot. I came back at 98 hours receptive. This is so confusing as… — Rachael K.
Dr. Geoffrey Sher answered
The blastocyst and the endometrium are in a constant state of cross-talk. In order for successful implantation to take place, the blastocyst must be at the appropriate stage of development and needs to signal a well synchronized endometrium to ‘accept it”. This dialogue between embryo and endometrium involves…
