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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Page 27 of 68

Immunology & Implantation Jan 3, 2024

KIR & HLA-C mismatch

Hi Dr Sher, I’m at a crossroads and desperate for advice. I’m 34 and my husband and I did 3 rounds of IVF to bank 4 euploid embryos. While I have low amh/DOR — my euploid rate was 80%. I… — Mel M.

Dr. Geoffrey Sher answered

WE should talk: I suggest you call my assistant, Patti at 702-533-2691 and set up an online consultation with me. When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up…
Early Pregnancy & hCG Jan 2, 2024

Embarazada

Quiero saber si estoy embarazada — Roxana A.

Dr. Geoffrey Sher answered

Please post in English! Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions (SFS) ; http://sherfertilitysolutions.com/sher-fertility-solutions-ebook.pdf Recurrent Pregnancy Loss and Unexplained IVF…
Egg Health & Ovarian Reserve Jan 2, 2024

Natural Ivf

Hello. 3 years ago I underwent a standard ivf. 13 follicles, 11 oocytes, 9 mature, 6 fertilized, 2 blasts, one very poor quality, one hatching AA resulting in my daughter. Now I am 39 years old, AMH 2,68 and I… — Helen C.

Dr. Geoffrey Sher answered

I would urge you not to do NC IVF. Consider the following options: Mini-IVF is a procedure that involves ovarian stimulation with oral fertility drugs such as clomiphene or letrozole to promote the development of follicles, for egg extraction. This is on the pretext that Mini-IVF, involves the…
Early Pregnancy & hCG Jan 2, 2024

withdrawal bleeding during estrogen and progesteron supplementation a week after FET

Dear Dr.Sher. I am an ENT doctor from Europe. I am diagnosed with PCOS and I have amenorrhea and no ovulation at all. One year ago my fertility doctor prescribed me Letrozol, because I wanted to conceive. Not only that… — Maria K.

Dr. Geoffrey Sher answered

It could be an implantation dysfunction due to another thin endometrium (endometrial insufficiency, Back in 1989, I conducted a study that examined how the thickness of a woman's uterine lining, known as the endometrium, affected the successful implantation of embryos in IVF patients. The study revealed that when…
Immunology & Implantation Dec 31, 2023

HLA Matching and Other Immunological Issues

Hi Dr. Sher, I was initially given your name from a friend of mine who had complex fertility issues and great success under your care. I have tested pregnant five times over the past 18 months and either had chemical… — Danielle K.

Dr. Geoffrey Sher answered

This is problematic because you have a total match + NK cell activation. This makes the chance of you carrying your own baby very small regardless of you being treated with LIT/steroids; IVIG/steroids or Intralipid/steroids. We should talk. I suggest you contact my assistant, Patti Converse at702-533-261 and…
IUI & Insemination Dec 31, 2023

Necesito información

Tengo 27 años busco un tratamiento de inseminacion in vitro sufro de síndrome de ovarios poliquisticos — Gresia U.

Dr. Geoffrey Sher answered

Please re-post in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility…
Early Pregnancy & hCG Dec 31, 2023

Pregnancy

My hcg level is 306 on 30/12/2023. LMP 18/11/2023. Abdominal ultrasound shows no embryo sac.Any complications? — Rizvana T.

Dr. Geoffrey Sher answered

Sadly, This sounds like a non-viable pregnancy. Going through IVF is a major investment, emotionally, physically, and financially, for every patient or couple. One of the most crucial moments is receiving the result of the blood test for human chorionic gonadotropin (hCG) pregnancy. It's a big deal! The…
Early Pregnancy & hCG Dec 31, 2023

Hcg level question

Hello! My LMP was 11/18/2023. On 12/18 I tested at 45 hcg, 12/22 I tested 183, and at 12/26 I tested at 1321 at 5 weeks and 3 days. Would you say this is a normal progression? I don’t have… — Sara W.

Dr. Geoffrey Sher answered

This could still be within an acceptable, viability range. An US in 1-2 weeks would be definitive. Going through IVF is a major investment, emotionally, physically, and financially, for every patient or couple. One of the most crucial moments is receiving the result of the blood test for…
IVF Failure & Pregnancy Loss Dec 31, 2023

Chemicals pregnancy

I had 4 chemical pregnancies what should I do — Selemawit Z.

Dr. Geoffrey Sher answered

When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
Embryos & Genetic Testing Dec 29, 2023

Mosaic embryo

Hello! My husband and I are doing IVF because he has ADPKD and we are trying to chose an embryo without that condition. We thankfully produced two healthy embryos (female) and one male without the ADPKD gene, negative segmental aneuploidy… — Loren S.

Dr. Geoffrey Sher answered

Human embryo development is a marvel of intricate processes, including reprogramming, sequential cleavage divisions, mitotic chromosome segregation, and embryonic genome activation. However, the journey towards a successful pregnancy is not without its challenges, as chromosomal abnormalities can occur during germ cell and preimplantation embryo development, leading to early…
IVF Failure & Pregnancy Loss Dec 28, 2023

Quisiera tener una niña por un vidrio

Quisiera tener una niña por un vidrio porque murió también mi esposo y mi esposo siempre querido una niña — Diana R.

Dr. Geoffrey Sher answered

Please repost in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility…
Embryos & Genetic Testing Dec 23, 2023

Multiple Chemical Pregnancies

Hi Dr. Sher, This has been a long journey. I did a fresh transfer at 38 (got 18 eggs, 5 to blast stage, but we did not test then), the fresh transfer resulted in a chemical. Had to take some… — Mary R.

Dr. Geoffrey Sher answered

On the face of it, this sounds very much like3 "implantation dysfunction). Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as…
Immunology & Implantation Dec 20, 2023

FET + Intralipids + Medrol + Heparin = Miscarriage

Hi Dr. Sher, I listened to your podcast on RPL with Dr. Aimee on The Egg Whisperer. I'm 44F, I've had 2 FET's with 2 tested 4AA embryos. Both implanted, both failed to grow. I was on the kitchen sink… — Marissa D.

Dr. Geoffrey Sher answered

WE need to talk. Might I recommend that you call my assistant, Patti Converse at 702-533-2691 to set up an online consultation with me to discuss. Geoff Sher
IUI & Insemination Dec 20, 2023

Seeking advice – IUI + letrozole

Hi Dr. Sher, I listened to the podcast on IUI with you and Dr. Aimee, the egg whisperer and I wanted to reach out to you in hopes of seeking your advice. I am a 34 year old who is… — Mallory F.

Dr. Geoffrey Sher answered

My bigger concern is that you might have an immunologic inmmplantation dysfunction and if so , IUI alone wont bve effective. This could explain your losses too. Between 2% and 5% of women in their childbearing years deal with hypothyroidism, a condition that affects women more than men.…
Infertility Basics Dec 18, 2023

Quiero tener un bb tengo 55 ano

Quiero tener un bb — Neibe C.

Dr. Geoffrey Sher answered

Please re-post in English! Geoff Sher

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

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