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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Answers from our doctors

Search 1,006 questions patients have already asked, or narrow them by topic.

  1. Uterine & Endometrial Health

    ERA question

    Dear Dr. Sher, Do you believe in the ERA? We did a modified natural mock cycle. Biopsy was performed at 158.5 hours after a took my trigger shot. I came back at 98 hours receptive. This is so confusing as… — Rachael K.

    Dr. Geoffrey Sher answered

    The blastocyst and the endometrium are in a constant state of cross-talk. In order for successful implantation to take place, the blastocyst must be at the appropriate stage of development and needs to signal a well synchronized endometrium to ‘accept it”. This dialogue between embryo and endometrium involves…

  2. Enseminacion invitro

    Siento esterilizada puedo embarazarme — Irlanda R.

    Dr. Geoffrey Sher answered

    Please post in English please.

  3. Egg Health & Ovarian Reserve

    Stimulation poor responder

    Advice on stimulation proctol please. Background: I’m 36y, normal BMI, pelvic and bowel endometriosis (lap confirmed and excised), high activated NK cells, persistently raised cardiolipin IgM titre, 3+ yr history primary infertility.5 failed embryo transfers. I did have brief chemical… — Maya G.

    Dr. Geoffrey Sher answered

    A. Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing…

  4. Egg Health & Ovarian Reserve

    Mistake on one dosage

    Hi Dr Sher, On the 5th day of my FSH treatment with Gonal-F only, I made a mistake and used Pergoveris instead of Gonal-F (same dosage), It's the same follitropin alfa, but I am afraid of the LH surge, that… — Jennifer S.

    Dr. Geoffrey Sher answered

    I don't think it will be a problem. I would not cancel...but discuss with your own RE. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your…

  5. IVF Failure & Pregnancy Loss

    Chemical Pregnancy

    TTC 3+ years. One Tube removed from ectopic 17 years ago previous partner. AFC 11. 37years old. Elevated NK cells. 1 failed round of IVF. 3 IUI, 2 of which were recent and I had chemical pregnancy in both. One… — Anneka K.

    Dr. Geoffrey Sher answered

    Subject to confirmation through further consultation and testing, I believe your history to be highlyb suggestive of an implantation dysfunction (probably) partly or completely due to an immunologic cause. Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure…

  6. Early Pregnancy & hCG

    Bleeding as soon as I fall pregnant

    Medication plan help: I am currently going through IVF. I have one PGT-tested embryo. My last two pregnancies, as soon as I fell pregnant, I experienced severe bleeding. First pregnancy - natural conception - bleeding started on day 33 and… — Abs G.

    Dr. Geoffrey Sher answered

    Protocols differ from clinic tom clinic. While interesting, the information provided here is not comprehensive enough for me to provide an adequate opinion. I suggest you call my assistaznt, patti Converse at 702-533-2691 and set up an online consultation with me to discuss. Good luck! Geoff Sher PLEASE…

  7. Early Pregnancy & hCG

    No quedo embarazada

    Quiero salir embarazada — Aamy A.

    Dr. Geoffrey Sher answered

    Please re-post in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro Fertilization to Family: A Journey with Sher…

  8. Hormones & Ovulation

    Ovidrel dosage on low BMI

    Dear Dr. Sher, I am low BMI. Should I do 500mcg hCGr for trigger or is 250mcg enough? Thanks again for all the help, A.C. — Anne C.

    Dr. Geoffrey Sher answered

    500mcg Ovidrel! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro Fertilization to Family: A Journey with Sher Fertility Solutions…

  9. Uterine & Endometrial Health

    Invitro

    Se puede hacer un invitro si tube clamidia y mi utero está inflamado — Karina C.

    Dr. Geoffrey Sher answered

    Please post your comment/question in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro Fertilization to Family: A Journey…

  10. Egg Health & Ovarian Reserve

    Suspected endometriosis and low AMH.

    I have suspected endometriosis and very low ovarian reserve. Should I do a laparoscopy for endometriosis, then PRP therapy to increase my ovarian reserve before I retry IVF? Will this help? My last two attempts at IVF have only ever… — Aqsa G.

    Dr. Geoffrey Sher answered

    Unless you need surgery because of intractable symptoms or you require surgical treatment of ovarian endometriomas, I would not advocate laparoscopy at all. Your miscarriages could well be due to endometriosis-induced , immunologic implantation dysfunction. When women with endometriosis-related infertility seek treatment, they are often advised to try…

  11. Embryos & Genetic Testing

    embrion mosaico nivel bajo

    Buenas tardes Dr El resultado del examen PGT de mi esposa fue Sample ID Sample Barcode Result Sex Chromosomes Impacted Interpretation LB1 2023061467 Aneuploid XY +9 Abnormal LB2 2023061467 Mosaic XY -Y [mos] Low Level Mosaic Aconseja implantar el LB2… — Jose S.

    Dr. Geoffrey Sher answered

    Please re-post in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro Fertilization to Family: A Journey with Sher…

  12. Egg Health & Ovarian Reserve

    Omnitrope dosage

    Dear Dr. Sher, Should Omnitrope continue to be taken on the day of the trigger and the next day, all the way till egg retrieval day, or stop two days before, when FSH stops? And what's the optimal dosage? Thanks… — Anne C.

    Dr. Geoffrey Sher answered

    No! It stops on the day of the "trigger". Good luck! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro…

  13. Egg Health & Ovarian Reserve

    Empty follicles

    I am currently 33 years old and have already had 3 ICSIs. However, the first one was 5 years ago. Last year I stimulated for 2 days with 375 Gonal f and 75 Menopur and then with 225 Gonal f… — Monika O.

    Dr. Geoffrey Sher answered

    “Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely to happen when multiple attempts are needed to retrieve an egg from a follicle, indicating the egg may have chromosomal abnormalities. The…

  14. Egg Health & Ovarian Reserve

    Positive lads after 4th lit treatment

    Dear Dr. Sher, Thank you for your answer. I did take ivig before pregnancy was diagnosed. Took 30g ivig on ovulation and on positive hgc test but it faild to relax my immune system. I refuse to take steroids as… — Irit L.

    Dr. Geoffrey Sher answered

    I Did 3 lit treatments 1.5 years ago. Lads were negative. After the last pregnancy loss I did the 4th lit. Finally lad became weak positive 40%. Do you think that positive lads gives me a better chance to carry a pregnancy? A: I do not believe this…

  15. Ovarian Stimulation & OHSS

    Endometrial cavity fluid

    I’ve had ECF ever since a d&c and forcep removal of rpoc in Jan 2022. I’ve taken prophylactic abx, hysteroscopy with loa and normal lap, 2.5 months lupron and letrozole for adeno. Failed medicated FET. 1) should I do a… — Arielle M.

    Dr. Geoffrey Sher answered

    There is too much here to discuss with a short response. We should talk. If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or email her at

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