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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Dr. Geoffrey Sher

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Uterine & Endometrial Health Dec 5, 2023

Viagra

For thin lining I am considering trying viagra suppositories. Is there a difference between just using the regular tablet vs. Having it compounded? As info, with just estradiol, my lining seems to max out at about 7.2, hoping based on… — Tasha T.

Dr. Geoffrey Sher answered

Back in 1989, I conducted a study that examined how the thickness of a woman's uterine lining, known as the endometrium, affected the successful implantation of embryos in IVF patients. The study revealed that when the uterine lining measured less than 8mm in thickness by the day of…
Embryos & Genetic Testing Dec 5, 2023

Secondary Infertility

Hi Dr Sher Ive watched the egg whisper Dr aimee talk to you about implantation failure and I wanted to ask you your advice, I messaged you a few years ago and was very grateful for your response and advice,… — Ayesha A.

Dr. Geoffrey Sher answered

I am so happy that you ultimately succeeded. But now you do have the biological clock working against your egg/embryo quality. The most important determinant is no doubt the issue of egg/embryo quality. Here,age, ovarian reserve and your husband's sperm dysfunction all are the most important operative variables.…
Egg Health & Ovarian Reserve Nov 30, 2023

Hipogonadismo hipogonadotrópico

Buenas tardes tras azoospermia y un mes tomando citrato de clomifeno por tener la lsh fsh y testosterona baja me he realizado una analitica y han subido los tres parametros, ¿ eso quiere decir que el seminograba mejorara? Gracias un… — Danie L.

Dr. Geoffrey Sher answered

Please post your inquiry in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1. From In Vitro Fertilization to Family: A Journey…
Uterine & Endometrial Health Nov 30, 2023

Fluid in endometrium before FET

Hello, I am currently on day 14 of taking estrogen in preparation for a FET, but since Day 12, a small mount of fluid has been seen in the lining. The estrogen is working to build the lining an Friday… — Rebecca S.

Dr. Geoffrey Sher answered

In many cases, the fluid will absorb after a few days of progesterone. If it fails to absorb, the FET should be canceled and a hysteroscopy performed to look for a surface lesion in the uterine cavity. Please also note that if the endometrium was
Embryos & Genetic Testing Nov 30, 2023

Immune System issues

I just had a miscarriage at 5 weeks 4 days of a tested normal embryo 5 day AA PGT . And I tried to get pregnant for over 10 years. I was told I had an immunity disorder years ago,… — Sheyla M.

Dr. Geoffrey Sher answered

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Embryos & Genetic Testing Nov 30, 2023

Embryo testing

Hi, dr. Sher! Do you recomend PGT (NGS) on day 3 embryos? I m 51 and have two day 3 embryos and my clinic want to biopsy now, because they think they won' t make it to day 5. I… — Polona B.

Dr. Geoffrey Sher answered

Absolutely not! They should wait to see if they reach blastocyst and then biopsy for PGS/PGT. Remember, embryos that do not reach blastocysts are all abnormal anyway and would never have propagated a viable pregnancy had they been transferred earlier. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND…
Egg Health & Ovarian Reserve Nov 30, 2023

Autoimmune Protocol

Hi Dr Sher I have recently discovered your work and am curious if you think I should pursue an autoimmune protocol for IVF. I'm 40 years old and have undergone 2 unsuccessful cycles of IVF this year. I have been… — Jen M.

Dr. Geoffrey Sher answered

The fact that you have conceived before does not rule out an immunologic implantation dysfunction (IID). If so, you endometriosis and hypothyroid states would favor an autoimmune IID rather than alloimmune. However since treatment differs for each of these, a diagnosis is imperative. Your diminished ovarian reserve merely…
Nov 29, 2023

Quiero tener una niña

Ya que mi esposo no tiene yo creo que una niña — Diana R.

Dr. Geoffrey Sher answered

Please re-post in English! Geoff Sher
Immunology & Implantation Nov 28, 2023

Repeated miscarriages

Dear Dr. Sher, Just had my 6th miscarriage, natural conception with ivig and lit. I am disgnosed with partial dq-alpha gene match (0301) and elevated nk cells. We have a 4.5 years old son concieved naturaly and easily. My miscarriages… — Irit L.

Dr. Geoffrey Sher answered

Firstly, In order for treatment with IVIG or intralipid to work optimally, it must begin long before pregnancy is established. From your report it sounds as if the IVIG therapy only started after the pregnancy was diagnosed and that is too late. Second, treatment must of necessity also…
Immunology & Implantation Nov 27, 2023

Lmit treatment

Hi my wife and I have a partial dq alpha gene match our first child was Ivf my wife did intralipids and steroids clexane we conceived our son naturally 9 months after our daughter was born and she went back… — Dean W.

Dr. Geoffrey Sher answered

You were very lucky to conceive and have a successful pregnancy without using IVF with your immunotherapy. You are best advised to combine the two for this attempt! IMMUNOLOGIC IMPLANTATION DYSFUNCTION (IID) There is a growing recognition that problems with the immune function in the uterus can lead…
Egg Health & Ovarian Reserve Nov 27, 2023

preparation for ivf

Dear Dr. George I am a 36-year-old female struggling with fertility issues and preparing for IVF. My recent tests have shown an AMH level of 5 pmol/L in UK units, indicating possible low ovarian reserve. I typically experience late ovulation… — Maria S.

Dr. Geoffrey Sher answered

WHY DID MY IVF FAIL: HOW CAN I OPTIMIZE THE CHANCE OF SUCCEEDING NEXT TIME ROUND Geoffrey Sher MD If you've undergone in vitro fertilization (IVF) and didn't achieve a successful pregnancy, you may be wondering why. It's important to know that IVF outcomes can be unpredictable, but…
Egg Health & Ovarian Reserve Nov 27, 2023

Empty follicles

Hi. I did multiple rounds of egg freezing and two times although 6 follicles showed on ultrasound the lab retrieved just one. The doctor said i should consider donor eggs. I did these procedures in Lebanon and i was wondering… — J H.

Dr. Geoffrey Sher answered

“Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely to happen when multiple attempts are needed to retrieve an egg from a follicle, indicating the egg may have chromosomal abnormalities. The…
Embryos & Genetic Testing Nov 27, 2023

PGT-A embryos

Hi i recently just had a blighted ovum and was wondering wht really causes blighted ovums? The embryo was tested and it was a donor egg with my husband's sperm... can a normal embryo still b "normal " if the… — Susan K.

Dr. Geoffrey Sher answered

If the embryo was chromosomally normal, then you should consider the possibility that this due to implantation dysfunction. IVF FAILURE WITH “NORMAL” EMBRYOS: EXAMINING AND ADDRESSING ANATOMICAL AND IMMUNOLOGIC CAUSES. Geoffrey Sher MD Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially…
Embryos & Genetic Testing Nov 27, 2023

Miscarriage and Adenomyosis

Hi there I am 39 and since 33 have had recurrent miscarriages. I had two at 6.5 weeks and then a live baby and then 1 at 6.5 weeks that had two trisomies when tested. During that third miscarriage I… — Sophie T.

Dr. Geoffrey Sher answered

Adenomyosis can compromise implantation, but in my opinion this only occurs when the endometrial lining at the time of ovulation, hCG "trigger" or when progesterone treatment begins in cases of FET/embryo adoption etc. In fact in most cases adenomyosis is found in women who have had several babies,…
Uterine & Endometrial Health Nov 22, 2023

Endometrioma treatment

Hi Dr. Sher, I was diagnosed with endometriosis and 2 ovarian endometriomas 2yrs ago after I started having aching in my left pelvis. I’ve been reading PubMed and NIH articles and I’m searching for a doctor who can do the… — Jennifer P.

Dr. Geoffrey Sher answered

I suggest you contact Dr. Aykut Bayrak at LA-IVF Cinic, Century City, CA Sclerotherapy of Ovarian Endometriomas Geoffrey Sher MD The precise mechanism by which ovarian endometrioma causes infertility is unknown. In women with ovarian endometriomas, infertility is potentially associated with a decreased oocyte retrieval rate, reduced oocyte…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

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