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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Egg Health & Ovarian Reserve Jan 11, 2025

Dor Diagnosis

I’ve been diagnosed with Dor. First antagonist cycle only ended up with 4 follicles on trigger day after 10days of stimming. However, e2 never got above 380 and seemed to have dipped on trigger day to 373. Clinic still proceeded… — Avie H.

Dr. Geoffrey Sher answered

There is a great deal to discuss! I suggest that you contact my assistant, Patti (concierge@sherIVF.com ) and set up a time to discuss online. ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF Understanding the impact of age and ovarian reserve on the success of in…
Egg Health & Ovarian Reserve Nov 24, 2024

IVF

I am 28 and my husband is 27. My husband was diagnosed with male factor infertility 1 year ago (low count, low motility). Our first IVF round produced 17 eggs, 14 mature, 14 fertilized and 6 untested fair quality blasts.… — Payton D.

Dr. Geoffrey Sher answered

I do not think the reason for your failed cycles was due to the male factor. It sounds more like an implantation dysfunction. We should connect online and discuss this in depth. I think I can help. Please call my assistant, Patti Converse at 702-533-2691 and set up…
Egg Health & Ovarian Reserve Oct 30, 2024

Changes to a 4th cycle

I’m at a bit of a loss. Having ICSI for secondary infertility (1st child conceived naturally age 29) and just midway through my 3rd cycle. I have paid up for a 4th cycle already so I’m keen to get some… — Amy E.

Dr. Geoffrey Sher answered

WE would need to discuss this complex matter. I suggest you call my assistant, Patti Converse (702-533-2691 and set up an online consultation with me. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my…
Egg Health & Ovarian Reserve Oct 28, 2024

Advice for last IVF round

Dear Dr. Sher: Thank you for hosting this forum. I am just shy of 41 with social infertility and have had two failed IVF cycles. The first used an antagonist protocol at 300 IU gonadotropin and resulted in one whole… — Claire C.

Dr. Geoffrey Sher answered

Please read what follows and thereupon, might I suggest that we talk . Please call my assistant. Patti at 702-533-2691 and set up an online consultation with me to discuss. The journey of in vitro fertilization can be a rollercoaster of emotions for many patients. Often times they…
Egg Health & Ovarian Reserve Oct 16, 2024

Adderall for DODR

Hello- I'm hearing a lot about the value of Adderall for patients with DOR and difficulty with implantation. Is there any data for this? What are the risks/benefits? Thank you! — Kristen S.

Dr. Geoffrey Sher answered

Respectfully, to my knowledge there is no data to support this. ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims…
Egg Health & Ovarian Reserve Oct 7, 2024

“Empty follicles”

Dr. Sher, I have a problem with my right ovary. Every time if we have more than one follicle > 17 mm in diameter on this side, we cannot retrieve the eggs (experienced that 3 times). We tried multiple protocols,… — Patricia K.

Dr. Geoffrey Sher answered

I suggest you call my assistant "Patti" (702-533-2691) and set up an online consultation with me to discuss...see below. EMPTY FOLLICLE SYNDROME” “Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely…
Egg Health & Ovarian Reserve Oct 1, 2024

Too many immature eggs

My daughter just completed her 2nd round of IVF. The first round yielded 7 out of 9 mature eggs but only one good blastocyst. This round yielded 14 eggs, and only 2 were mature. Only one of those fertilized &… — Eileen H.

Dr. Geoffrey Sher answered

Embarking on the journey of IVF often raises questions about the likelihood of success and the quality of embryos. While it’s challenging to predict outcomes due to various factors, there’s hope and information to guide you. Firstly, the key to fertilization potential lies in the chromosomal integrity of…
Egg Health & Ovarian Reserve Sep 30, 2024

Bad quality eggs

Dear Dr. Sher. I am out of options i feel. Unknown fertility problem, endometriosis. I am now 30 years old. For the last 5 years: 5 IVF/ICSI cycles, 65 mature eggs, 30 fertilized, 0 good blastocyst, only poor quality, nothing… — Maggy M.

Dr. Geoffrey Sher answered

Embarking on the journey of IVF often raises questions about the likelihood of success and the quality of embryos. While it’s challenging to predict outcomes due to various factors, there’s hope and information to guide you. Firstly, the key to fertilization potential lies in the chromosomal integrity of…
Egg Health & Ovarian Reserve Sep 30, 2024

It’s over

Dear Dr. Sher, I am 43 years old, and in the last 2 years: 6 cycles, 100 follicles, 90 oocytes collected, 60 oocytes matured, 50 embryos, 10 blastocytes, 1 euploid. One abortion (prior to ivf), two failed transfers (the euploid… — Anne C.

Dr. Geoffrey Sher answered

I think we should talk first before you make that determination definitively. If you are interested in having an online consultation with me, please contact my assistant, Patti Converse at 702-533-2691 or email her at concierge@sherivf.com\ Geoff Sher ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF…
Egg Health & Ovarian Reserve Sep 19, 2024

poor egg quality

Im 37F no other medical history. AMH 2.01, Day 3 FSH 5.7, estradiol 56. Have done two cycles of IVF: First cycles I was on menopur (150) and gonal (initially 150 and bumped to 300) for about 11 days with… — Serena B.

Dr. Geoffrey Sher answered

In my opinion, you are young enough and have a normal ovarian reserve, such that egg quality should not likely be an inherent problem. In such cases, it is very often the protocol used for ovarian stimulation that plays a role here. It needs to be individualized to…
Egg Health & Ovarian Reserve Sep 17, 2024

IVF for Diminished Ovarian Reserve

I'm interested in speaking with only the best doctors as it relates my fertility. I look forward to speaking with you soon. I turned 49 recently. My odds of pregnancy with my own eggs are a long shot. I tell… — Teresa G.

Dr. Geoffrey Sher answered

At 49y, your only rql option is IVF with Egg donation....I am afraid, Geoff Sher IVF WITH EGG DONATION: A REVIEW Introduction: Egg donation is when a woman donates her eggs for assisted reproduction or research purposes. In assisted reproduction, it usually involves using IVF technology, where the…
Egg Health & Ovarian Reserve Sep 12, 2024

Low AMH, high AFC

I’ve been doing fertility treatments for five years. I have two kids. One with an IUI at age 35, one with IVF at 37. I’m now 40 and keep having trouble. My AMH is now .1, but my afc is… — Sara Q.

Dr. Geoffrey Sher answered

There is a high likelihood that aside from the age factor impacting egg quality, your severely diminished ovarian reserve sets you up fro what is known as "premature Luteinization". This is particularly more likely if the protocol used for ovarian stimulation is not optimally fashioned. ADDRESSING ADVANCING AGE…
Egg Health & Ovarian Reserve Aug 26, 2024

Same Agonist/Antagonist Conversion Protocols with Very Different AFC 6 Months Apart

Dr. Sher, I convinced my IVF doctor to let me use your agonist/antagonist conversion protocol with Zomacton (using Ganirelix to replace Lupron and keep using it until trigger date). My March cycle resulted in 4 eggs retrieved, 3 fertilized, unfortunately… — Meredith S.

Dr. Geoffrey Sher answered

There can be a very rapid decline in AFC at your age . This is because of inevitable decline in ovarian reserve and in egg quality. If you wish, you coulkd call my assistant Patti Converse at 702-533-2691 and set up an online consultation with me to discuss…
Egg Health & Ovarian Reserve Aug 26, 2024

Protocol for second round after low maturity in the first

Hi Dr Sher, We recently embarked on IVF after 1x TFMR at 24 weeks for genetic disorder (22q syndrome) of which neither me or my partner are carriers followed by 3x chemical miscarriage around 4.5/5 weeks. Our first cycle was… — Victoria L.

Dr. Geoffrey Sher answered

We should talk. There is no doubt in my my mind that the protocol used for ovarian stimulation has to be individualized to optimize egg/embryo "competency. I invite you to call 702-533-2691 and ask my assistant, Patti Converse, to set up an online consultation with me to discuss.…
Egg Health & Ovarian Reserve Aug 16, 2024

CoQ10

I am 43 years old with AMH of 3. My egg retrieval was yesterday. My HCG trigger did not absorb after 7 days of Stims and no priming starting on day 5 of my period. I was given 150 meno… — Kristin H.

Dr. Geoffrey Sher answered

The COQ10 likely had nothing to do with your follicle development. However, the protocol used for ovarian stimulation and/or its implementation, probably underlies your issue.We should talk: Please call my assistant, Patti Converse (702-533-2691 and set up an online consultation with me. EGG/ EMBRYO QUALITY IN IVF &…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

165 answers

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