Blog - Sher Fertility Solutions

Raised Blood Prolactin

By Dr. Geoffrey Sher

Prolactin (PRL) is a protein hormone (closely related to human growth
hormone
[https://drgeoffreysherivf.com/human-growth-hormone-administration-in-ivf-does-it-enhance-eggembryo-quality-and-outcome/])
that is secreted by specialized cells in the anterior part of the
pituitary gland. In addition, the hormone is also produced and
secreted by a broad range of other cells in the body, most prominently
various immune cells, the brain, and the endometrium (lining of the
uterus).Â Â…

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Diminished Ovarian Reserve: The Sher Philosophy

By Dr. Drew Tortoriello

It appears from my vantage point that the proportion of patients
suffering from diminished ovarian reserve is on the increase.

This increase is likely due to several reasons:

* Social/lifestyle: Many women are deliberately delaying their
childbearing to focus on other aspects of their life, including the
furtherance of their education and their career objectives.

* Environmental issues: As technology advances, we are constantly
being exposed to new food addi…

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Acupuncture and IVF: Does it Improve Success?

By Dr. Geoffrey Sher

Acupuncture involves the insertion of thin needles into the skin along
so called meridians (energy channels). It has been used in China for
centuries to regulate and treat many health disorders including
ailments involving the female reproductive system.
When I visited China back in 1987, I actually witnessed a Cesarean
birth being performed without sedation, pain killers or anesthesia…
using only acupuncture. The mother lay there relaxed, conversing with
the surgeon and…

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Endometriosis and IVF

By Dr. Geoffrey Sher

When women with infertility due to endometriosis seek treatment, they
are often advised to first try ovarian stimulation (ovulation
Induction) with intrauterine insemination (IUI). As with essentially
all reasons for infertility, IVF offers a much higher chance of
success than proceeding with multiple IUI cycles in endometriosis
patients. This is not to suggest that all women with
infertility-related endometriosis should automatically resort to IVF.
Quite to the contrary; in spi…

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Why did IVF fail?

By Dr. Geoffrey Sher

Whenever a patient fails to achieve a viable pregnancy following
embryo transfer (ET), the first question asked is “Why?”

Was it simply due to bad luck? How likely is the failure to recur in
future attempts and what can be done differently to avoid it happening
next time?.
It is an indisputable fact that any IVF procedure is at least as
likely to fail as it is to succeed. Thus when it comes to outcome,
luck is an undeniable factor. Notwithstanding, it is incumben…

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Embryo Transfer: Simply Crucial in IVF

By Dr. Geoffrey Sher

Embryo transfer (ET) is undoubtedly a rate limiting factor in IVF. The
IVF doctor’s expertise in performing ET is one of the most important
factors determining IVF outcome. It requires the dexterity, skill, and
gentle touch that can only truly come through experience. Of all the
procedures in IVF, this is the most difficult to teach. It is a true
“art” and there is little doubt that many women will fail to
conceive following IVF from a suboptima…

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A Thin Uterine Lining: Vaginal Viagra may help

By Dr. Geoffrey Sher

In 1989, Dr. Sher first published a study that examined the
correlation between the thickness of a woman’s uterine lining (the
endometrium), and the odds of embryo implantation in IVF patients.
This study revealed that when the uterine lining measured at least 9mm
in thickness by the day of the “hCG trigger” (in fresh IVF
cycles), or at the time of initiating progesterone therapy (in embryo
recipient cycles, e.g. frozen embryo transfers-FET, egg donation-IVF
etc.) , pregna…

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Diagnosing and Treating Immunologic Implantation Dysfunction (IID)

By Dr. Geoffrey Sher

Central to making a diagnosis of an immunologic implantation
dysfunction (IID) is a need for the appropriate interpretation of
Natural Killer Cell Activity (NKa). In this regard, one of the
commonest and most serious errors, is interpret the blood
concentration of natural killer cells as being relevant. Rather it is
the activity (toxicity) of NK cells that matters as mentioned. This
activity can best be measured using the blood, K-562 target cell test
(the gold standard). and/ o…

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Raised Blood Prolactin Levels (Hyperprolactinemia) in Women Undergoing Infertility Treatment

By Dr. Geoffrey Sher

Prolactin (PRL) is a protein hormone (closely related to human growth
hormone
[https://blog.drgeoffreysherivf.com/human-growth-hormone-administration-in-ivf-does-it-enhance-eggembryo-quality-and-outcome/])
that is secreted by specialized cells in the anterior part of the
pituitary gland. In addition, the hormone is also produced and
secreted by a broad range of other cells in the body, most prominently
various immune cells, the brain, and the endometrium (lining of t…

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What Is Diminished Ovarian Reserve?

By Dr. Geoffrey Sher

Ovarian reserve refers to the reproductive potential left within a
woman’s two ovaries based on number of eggs (oocytes). If you have
diminished ovarian reserve, this means that the number of your eggs is
lower than expected for your age. Although the relative quality
(chromosomal normalcy or competency) of eggs in DOR patients may also
be compromised, we often see quality being more aligned with a
patient’s age rather than her number of eggs.
Normal aging causes mos…

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