IVF: FACTORS AFFECTING EGG/EMBRYO “COMPETENCY” DURING CONTROLLED OVARIAN STIMULATION (COS)
The potential for a woman’s eggs to undergo orderly development and maturation, while in large part being genetically determined can be profoundly influenced…
Sher Fertility Solutions
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Ten years of writing on IVF, fertility and reproductive medicine from Sher Fertility Solutions. Ten years of writing on IVF and fertility.
Preimplantation Genetic Sampling (PGS) Using: Next Generation Gene Sequencing (NGS): Method of Choice
About 10 years ago, Levent Keskintepe PhD and I introduced
Centers for disease control (CDC)IVF: The Economic Realities
Patrick Steptoe and Robert Edwards were responsible for the birth of the world’s 1st IVF baby, Louise Brown, in 1978. Since then about >5…
Egg Freezing and Banking: What are the Merits? (Case Report)
Hi Dr Sher, I am considering pursuing egg freezing in a few months. I had an initial consult with and RE in which…
Embryo Banking/Stockpiling: Slows the “Biological Clock” and offers a Selective Alternative to IVF-Egg Donation
An ever increasing number of American women first seek
Endometriosis and Infertility
Endometriosis is a condition that occurs when the uterine lining (endometrium) grows not only in the interior of the uterus but in other…
Selective Banking of Genetically Tested Donor Eggs
 As a woman ages beyond 30 years, the quality of her eggs starts to decline progressively and with it also her fertility potential.…
Egg Donation-Fashioning Rational Expectations: Preparation; Donor Selection; Using Fresh versus Frozen (Banked) Eggs; Financial/Ethical Considerations; The Process; Outcome!…
For many women, disease, the physiological decline in ovarian reserve (DOR) and spontaneous or pathologically induced menopause will preclude pregnancy using own eggs. For…
Immunologic Implantation Dysfunction (IID) -Making the Diagnosis
Currently there are fewer than a dozen immunology reference laboratories in the U.S that are capable of analyzing the required elements with a sufficient…
Immunologic Implantation Dysfunction (IID): Treatment
In the United States, effective treatment of NK/CTL activation associated with either alloimmune or autoimmune implantation dysfunction requires the administration of primarily Intralipid (IL)or…
IVF-Gestational Surrogacy: An Overview
IVF surrogacy involves the transfer of one or more embryos into the uterus o...
Launching Ovarian Stimulation with a BCP: How Does it Affect Response?
One often hears the expressed opinion that the BCP suppresses response to ovarian stimulation. This is not the case, provided that the BCP…
Frozen Embryo Transfer (FET): What Does it Involve?
Frozen Embryo Transfer (FET) A frozen embryo transfer cycle is initiated by administering an oral contraceptive (OC) to the recipient. This is later…
Immunologic Implantation Dysfunction (IID) & Infertility (IID): PART 1-Background
In 15-20% of women who have infertility or RPL, the cause will be immunologic implantation dysfunction (IID). Accordingly, all women who have predisposing…
Implications of Empty Follicle Syndrome and Premature Luteinization
Frequently, when following vigorous and often repeated flushing of follicles at egg retrieval they fail to yield eggs, it is ascribed to “Empty…
Preventing Severe Ovarian Hyperstimulation Syndrome with “Prolonged Coasting”
I do not use antagonists in high responders (e.g., PCOS) because it interferes with the assay of E2 (often causing the value to…
Secondary Infertility: Addressing the Root Causes
It is one thing for a woman who has never been able to conceive (primary infertility) to come to grips with undergoing In…
Staggered IVF: An Excellent Option When Advancing Age and Diminished Ovarian Reserve (DOR) Reduces IVF Success Rate
Many physicians treating infertile women over 40 years old who have patent fallopian tubes still opt to start with the least invasive strategy…
The Role of Nutritional Supplements in Preparing for IVF
It is important to take care of yourself mentally and physically when preparing and going through your IVF journey. This starts with trying…
Thyroid autoantibodies and Immunologic Implantation Dysfunction (IID)
Between 2% and 5% of women of the childbearing age have reduced thyroid hormone activity (hypothyroidism). Women with hypothyroidism often manifest with reproductive…