Dr. Geoffrey Sher

Overcoming Age Barriers in IVF and Embracing New Pathways to Parenthood: Unlocking the Possibilities

Age should never be a barrier to hope and fulfillment when it comes to IVF. Many women in their early to mid-40s are successfully having IVF babies using their own eggs, especially if they have a good number of eggs left in their ovaries. However, for women with diminished ovarian reserve (DOR) or those over

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IVF Failure With “Normal” Embryos: Examining and Addressing Anatomical and Immunologic Causes

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success rates have been improving in the past

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Egg/Embryo Quality in IVF & How Selection of the Ideal Protocol for Ovarian Stimulation Influences Egg/Embryo Quality and Outcome

The journey of in vitro fertilization can be a rollercoaster of emotions for many patients. Often times they have to face the harsh reality that the number and quality of eggs retrieved has fallen short of their expectations. Then, should fertilization of these eggs not propagate chromosomally normal (euploid), “competent” embryos suitable for transfer to

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Embryo Implantation Dysfunction

Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. This is especially relevant in cases of unexplained IVF failure, recurrent pregnancy loss (RPL), and in women with underlying endo-uterine surface lesions, thickness of the uterine lining (endometrium) and /or immunologic factors. IVF success rates have been improving over the last decade.

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Disruption in the relationship between KIR, HLA, and NK cell activity and embryo implantation dysfunction: how to assess this

I constantly receive inquiries from “confused” patients with unexplained recurrent IVF failure , unexplained infertility, recurrent pregnancy loss etc. (where an immunologic implantation dysfunction (IID) is often underlying) as to the relevance of measuring Killer Cell immunoglobulin Receptors (KIR) and Human Leukocyte Antigens (HLA).

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Why IVF is the treatment of choice when it comes to Infertile Women over 40Y

Consider the fact that at age 40-43 years, the birth rate per cycle of treatment with injectible fertility drugs alone, or in combination with intrauterine insemination (IUI) is about 2% and 10-15 times higher with IVF performed in an IVF program of excellence. It follows that for childless women for whom the biological clock is

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Treating Endometriosis Related Infertility: Dr. Geoffrey Sher & Dr. Aimee

This article and interview originally aired on The Egg Whisperer Show with Dr. Aimee, and can be seen here: https://draimee.org/treating-endometriosis-related-infertility-with-guest-dr-geoffrey-sher You can also see the Apple Podcast at The Egg Whisperer Show: Treating Endometriosis Related Infertility with guest Dr. Geoffrey Sher on Apple Podcasts You can also watch the video on our SFS YouTube Channel

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Causes of Infertility

Infertility is defined as inability to conceive in spite of engaging in well-timed unprotected sex for more than one year. The causes of infertility are multiple and are often difficult to define but may include anatomical conditions involving tubal patency and/or function as well as diseases of the testicles and/or or sperm ducts, dysfunctional levels

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