Dr. Geoffrey Sher

Ovulation occurs within 38-42 hours of initiation of the spontaneous
luteinizing hormone (LH) surge (which can be detected in the blood or
urine prior to this event) and/or hCG administered
following controlled ovarian stimulation (COS)…

Antisperm antibodies (ASA) are immunoglobulins that attach to sperm.
They are most commonly encountered in semen, blood, cervical mucous
and follicular fluid. Not all ASA bind to sperm; however, those that
do so can inhibit fertilization. The current methods of detecting
the presence of SAs in blood, in the seminal plasma of the ejaculate
or in the cervical mucus only measure those immunoglobulins that bind
to sperm components. ASAs are related to the …

Ideal egg development sets the scene for optimal egg maturation that
occurs 36-42h prior to ovulation or egg retrieval. Without prior
optimal egg development (ovogenesis), egg maturation will be
dysfunctional and most eggs will be rendered “incompetent” and
unable upon fertilization to propagate viable embryos. In IVF, optimal
ovogenesis requires the selection and implementation of an
individualized approach to

Approximately 1 out of every 100 embryos will implant and grow outside
of the uterine cavity, almost always in a fallopian tube. This is
defined as an ectopic pregnancy. Infrequently, an ectopic pregnancy
attaches to an ovary or to one or more other pelvic organs. On very
rare occasions (1:1,000), one twin attaches and grows in the uterine
cavity with the other growing outside the uterus (i.e. a heterotopic
pregnancy). There is an ever present risk that a tubal (ectopic)
pregnancy might …

Given the considerable emotional, physical and financial investment
associated with IVF treatment
[/blog/confronting-the-real-cost-of-ivf-treatment/], it is essential
that factors known to affect success be identified and regulated in
advance of initiating treatment and to always thoroughly and
meticulously “plan the trip before taking the ride.” This article
addresses the most important considerations in this regard:…

An ovarian cyst [http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024724]
is any collection of fluid, surrounded by a very thin wall, within an
ovary [http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0022599]. An

What is a varicocele? The testicles are housed in the scrotum, a
skin-covered sac that houses the two testicles as well as blood
vessels that deliver blood to these glands, nerves, and lymphatics. An
abnormality of the plexus of veins (the pampiniform plexus) that carry
blood away from the testicles can result in their distention,
proliferation and enlargement within the scrotum. We refer to this as
the development of varicosities similar to varicose veins…

About seventeen years ago, after reporting on the benefit of vaginal
Sildenafil (Viagra) for women who had implantation dysfunction due to
thin endometrial linings, I was proud to announce the birth of the
world’s first “Viagra baby.”  For those of you who aren’t
familiar with the use of Viagra in IVF, allow me to provide some
context.

There is an ever growing realization, recognition, and acceptance of
the fact that uterine immunologic dysfunction can lead to immunologic
implantation dysfunction (IID)
[/blog/diagnosing-and-treating-immunologic-implantation-dysfunction-iid/]
with “unexplained” infertility, IVF failure
[/blog/unexplained-ivf-failure/], and…

More and more women are deciding, based upon personal preference and
professional necessity, to postpone having a family to a later age. In
fact, very recently Janet Jackson (49Y) was in the news stating that
she was cancelling her tour to prepare for treatment needed to have a
baby. This event prompted me to write this article on IVF in women of
a more advanced age The truth is that hardly a day goes by when I am
not asked the question of, “How old is too old to do IVF?” The
standar…