IVF – Friend of Ivan Sher

Hello, I am 41 years old. I am a friend of Ivan Sher’s for many years and he mentioned I could get some help from Dr. Sher on here. My AMH levels are 2.87. We started IVF when I was 40, in July 2022. Mainly because of reasons not for me. In July we retrieved 27 eggs, 25 mature, 17 fertilized, 7 embryos, after PGT 1 normal and 1 low level +19 mosaic. We used fresh sperm. CoQ10 and prenatal vitamins only supplements. Second retrieval in September 2022. 27 retrieved, 25 mature, 22 fertilized, 9 embryos, 2 normal after PGT and 1 inconclusive. We used fresh sperm again and same supplements. Did a transfer in October and I was pregnant. Mis carried at 9 weeks, end of November. Did a second transfer in January and that transfer failed. switched doctors. Did a mock trial. Doctor said I have a little bit of andemyosis on one part of my lining that we will supress for 3 months with Lupron Depot then we can do a 3rd transfer in June. I said I will do a 3rd retrieval to try and bank more embryos for the future. I asked if we should supress before retrieval and they told me no that my ovaries don’t have anything to do with my uterus and the andemyosis is only on my uterus. March 2023 i do my 3rd retrieval. We received 32 eggs, 21 mature, 15 fertilized and ONLY 1 EMBRYO THIS TIME which is currently out for PGT. I was in complete shock with the difference in my results. We used Frozen Sperm this time and an entire list of supplements the doc gave me. I asked my Doctor WHY this happened ? He said either the frozen sperm didn’t work well or my andemyosis progressed and stimulated during stim. I told him I had asked to supress prior to the retrieval and they told me I don’t need to and he said that we didn’t know It progressed and obviously they still don’t know. It is just a guess either that happened or it’s the frozen sperm. I’m incredibly frustrated. Last Friday I took my first shot of Lupron. I have one normal and one embryo left and one out for PGT … God knows if that one will come back normal. I’m 41.5 now and I just want to have our baby. I really don’t want to do a 4th retrieval and want to just transfer in June. My question is, why do you feel my results this time came back with almost no embryos ? Doc said most arrested around day 4 and 5. I wish they had called me at Day 3 to update me. Any advice on what I should do next after I am on this Lupron for 3 months ? I’m worried if i do a 4th retrieval and then a frozen transfer 5 days after in June, I risk my embryo implanting due to my andemyosis being triggered again from stims, even after Lupron. I was thinking either to do a 4th retrieval in June and transfer 3 day 3 fresh embryos from that retrieval as to not risk losing embryos again and then if there are more embryos, freeze them and send out for PGT testing. That way I still have one normal and one mosaic frozen and if June transfer fails, i can do another transfer in July with a frozen. I am trying to not waste time. Luckily I have a high egg count but this process has been very frustrating and disheartening. a lot of trial and error. I don’t believe i ever had endometriosis or andeymosis before starting IVF. I have been pregnant naturally before. I would love to hopefully hear back from you. I really appreciate your advice. Ivan speaks so incredibly highly of you !!! I wish I could meet you ! you have helped some friends of mine as well.