Dr. Geoffrey Sher

Case Report: Can Intralipid/Steroid Therapy be Used Without Undergoing IVF?

_Question posed by by Patient X: _ Can oral steroids (prednisone) and
IL therapy be done without IVF? I have had 2 failed IUI’s 2 years
ago, but I do not like taking ovulation stimulating hormones. I have
endometriosis (not sure of what stage), am not currently working with
an RE, and have been TTC for 6 years. I have a higher than normal for
TTC TSH level (3.5-4), am 34Y/O, totally normal and regular periods
with ovulation almost every month, and husband checks out with good
numbe…

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The Number of Embryos/Blastocysts Transferred & PGT: Effect on IVF Outcome:

A “competent” embryo is one that is chromosomally, genetically and
metabolically capable of propagating a viable conceptus in-utero. Such
an embryo will have the same chance of resulting in a baby whether it
is transferred cleaved( on day 2,3,4) or as a blastocyst (day 5 or 6),
post-fertilization. Currently, we have no ability to reliably assess
the genetic and metabolic integrity of an embryo. The only tools we
currently have to rely on are: a) the embryo’s microscopic
appearance …

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Case Report: Egg Donation-Mother Uses her Daughter’s Eggs to conceive

The case involves D.R, a recently remarried, premenopausal woman in
her late 40’s, who had a daughter (N.R.) some 33Y ago, in a prior
marriage. D.R. inquired whether I would be willing to do IVF on her
daughter, fertilize the eggs with her husband’s sperm and then
transfer the embryos to her (DR’s) uterus. Needless to say, it was
recognized that if successful, and D.R. were to give birth to a baby
born from NR’s eggs, she would be giving birth to her own genetic
grandchild who wo…

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Case Report: The Diagnosis of “Unexplained” Recurrent IVF-Failure is Sometimes a Cop-out

Ingrid (37y) and Jesse 41y had been trying to conceive for 6 years.
The couple was “thoroughly tested” and had been “labeled” as
having _“unexplained infertility”._ Ingrid had patent fallopian
tubes, a normal (regular) uterine cavity, was experiencing regular and
normal menstrual cycles and her ovulation was found to be normal with
adequate supporting hormonal environment. Jesse had normal sperm
parameters and had in fact initiated a pregnancy in a previous
relationship,…

Case Report: The Diagnosis of “Unexplained” Recurrent IVF-Failure is Sometimes a Cop-out Read More »

Case Report: IVF in a 32y old with Premature-Menopause Following Cancer Chemotherapy.

Malia (33y) and her husband, Paul (41y), presented to me a few months
back. with 3 years of primary infertility (she had never conceived in
the past). Paul had initiated 3 pregnancies in a previous marriage and
by all tested parameters, was fertile. Malia on the other hand, was
menopausal with absent ovulation and menstruation. She had been
diagnosed with and treated for Leukemia 12 years prior and had been in
full remission for the last decade. However, her chemotherapy had
caused progr…

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Case Report: Intractable Damage to the Uterine Lining (Asherman Syndrome ) causing Failed Implantation

Marissa (39y) and her husband, Pete (43y) presented with a history of
having had 2 healthy children together. Marissa was a normally
menstruating/ovulating lady with a fertile husband. The birth of her
2nd child was complicated by partial delivery of the placenta and
  was accompanied by a post-partum hemorrhage (bleeding). A manual
removal of the retained piece of placenta was undertaken following
which her uterus was deemed to be empty. After the birth of her baby,
Marissa…

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Selecting the Ideal Protocol for Controlled Ovarian Stimulation!

 “IVF IS NEITHER A PURE ART OR A PURE SCIENCE. RATHER IT IS A BLEND
OF BOTH!”“Virtually nothing that we do clinically in IVF can be
fully supported or validated by “gold standard statistical analysis.
This is because in the ART setting, when it comes to establishing
comparative evidence of clinical efficacy, randomized controlled
statistical assessments cannot be applied.  Such determinations of
outcome would require stabilizing all…

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