Early Pregnancy & hCG
IVF
I am pregnant ! Thanks alot Dr Sher for answering my questions and relieving my anxiety . — Monica L.
Dr. Geoffrey Sher answered
Good luck and G-d bless! Geoff Sher
Ask Our Doctors
Supporting Your Journey
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
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Dear Patients,
I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.– Geoffrey Sher, MD
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Answers from our doctors
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Latest answers
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Embryos & Genetic Testing
Chromosomal Abnormalities
Can high doses of drugs used to stimulate the ovaries of older women undergoing fertility treatment may be causing chromosomal abnormalities in their eggs? — Tina M.
Dr. Geoffrey Sher answered
In my opinion...NO! G-d bless! Geoff Sher
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IVF
Hello Doctor Sher , Today is the eleventh day after my IVF and I am intending to do a blood test . The results are supposed to be countable right? Thanks alot for your platform by the way. — Monica L.
Dr. Geoffrey Sher answered
Correct!
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Embryos & Genetic Testing
Embryo
I recently got an embryo report back from coopergenomics and it's euploid, but my PGT-M result came back with maternal chromosome contamination. Do you think this can effect success rates? — Julie G.
Dr. Geoffrey Sher answered
You need to discuss this with your personal RE. Good luck! Geoff Sher
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Embryos & Genetic Testing
Blastocysts
Are two healthy blastocyst enough for a successful implantation? I need to talk to you doctor privately , I live in a very far country and I can't see you , is it possible to discuss my situation with you… — Monica L.
Dr. Geoffrey Sher answered
I transfer up to 2 blastocysts at a time...but no more. Please call my assistant Patti Converse at 702-533-2691 or email her at concierge@sherivf.com and set up an online consultation with me. Geoff Sher
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Immunology & Implantation
HLA/DQ Alpha
I have implantation dysfunction. 6 transfers of 7 embryos have failed (our last being a PGS normal). I do have low LADs but never got HLA/DQ Alpha testing. We have moved on to surrogacy with my husbands sister. Transferred a… — Karly W.
Dr. Geoffrey Sher answered
Implantation dysfunction is unfortunately often overlooked as an important cause of IVF failure. This is especially relevant in cases of unexplained IVF failure, recurrent pregnancy loss (RPL), and in women with underlying endo-uterine surface lesions, thickness of the uterine lining (endometrium) and /or immunologic factors. IVF success rates…
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Immunology & Implantation
DQa partial match
Hello Dr, My question is, it possible to just keep trying naturally in the hope that there will at some stage not be a match and a pregnancy will proceed normally without any intervention? I have had 4 miscarriages so… — Emma P.
Dr. Geoffrey Sher answered
DQ alpha matching is in my opinion only a problem if it is associated with NK cell activation (see below). When it comes to reproduction, humans are the poorest performers of all mammals. In fact we are so inefficient that up to 75% of fertilized eggs do not…
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Embryos & Genetic Testing
IVF
I have done an I VF and I am right now in the two week wait anxiety . I have tried 4 times previously and have a failure . The doctor this time did surgical scratching for the uterus ,… — Monica E.
Dr. Geoffrey Sher answered
I suggest you await the outcome and if you do not conceive, that you contact my assistant Patti Converse (702-533-2691) and set up a consultation online, with me. Good luck! Geoff Sher
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Age & Fertility
DGP
Hola, soy Juan Francisco Martínez , tengo 39 años, recientemente he sido diagnosticado de de una mutación en el gen que codifica la proteína Desmina, con leve repercusión cardiomiopática en el momento actual aunque hay antecedentes de muerte súbita en… — Martinez J.
Dr. Geoffrey Sher answered
Please post your question in English!
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Embryos & Genetic Testing
Day 6 and Day 7 euploid embryos
I'm 36 and doing IVF with PGT-A and PGT-M to avoid passing on a genetic condition I'm a carrier for. I don't have any identified fertility issues and have had a viable natural pregnancy before at age 34. I've had… — Charlotte D.
Dr. Geoffrey Sher answered
Frankly, you and I should have an in depth discussion to address these issues. I do not believe there is merit in transferring day 7 blastocysts whether or not they are euploid. The chance of pregnancy is dismal. There could be embryo issues relating to a possible deficiency…
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Embryos & Genetic Testing
Implantation failure
Hi Dr Sher. I am from New Zealand and almost 2 years on in my fertility journey. I’m 42 now and have 3 children of my own. My husband has 1. We are both fit and healthy. I’ve always had… — Barbara C.
Dr. Geoffrey Sher answered
Whenever a patient fails to achieve a viable pregnancy following embryo transfer (ET), the first question asked is why! Was it simply due to, bad luck?, How likely is the failure to recur in future attempts and what can be done differently, to avoid it happening next time?.…
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Embryos & Genetic Testing
Where to go after 3 rounds of egg retrieval
Hello Dr. I have had 3 MCs ( chromosome issues) 3 rounds of er, in total 34 eggs, 23 fertilized, 5 blasts no euploid, 1 failed fresh 3-day transfer. I am 40 started all this when I was 38. My… — Desiree B.
Dr. Geoffrey Sher answered
There is really a great deal to talk about here. I strongly urge you to call my assistant Patti at 702-533-2691 and set up an online consultation with me. Given your history of 3 losses I think that aside from an egg/embryo quality issue you could, in addition,…
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Male Infertility
Morphology
Hello Dr. Sher, My husband's semen analysis came back as 250 million motile sperm but only 4% morphology. Is such low morphology an issue in your professional experience? Does this mean that its basically 10 million sperm that are ok… — Lisa M.
Dr. Geoffrey Sher answered
This quite acceptable. I do not see it as a significant issue at all.when it comes to IVF/ICSI, Geoff Sher
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Immunology & Implantation
Infertility for 14 years
Hi, we have been facing recurring losses, dq alpha complete match, nk cells causing allergic reactions at the time of implantation. Is there anything you can suggest for us to be pregnant. I'm 40 and my husband 39, we don't… — Shama S.
Dr. Geoffrey Sher answered
When it comes to reproduction, humans are the poorest performers of all mammals. In fact we are so inefficient that up to 75% of fertilized eggs do not produce live births, and up to 30% of pregnancies end up being lost within 10 weeks of conception (in the…
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Early Pregnancy & hCG
Test
What test would you consider if someone had 4 miscarriages before 6 weeks I have done all the basic test Immune conditions Chromosome Ovarian reserve My husband sperm Protein Std Everything is normal No polyps I do have fibroids not… — Medjine E.
Dr. Geoffrey Sher answered
When it comes to reproduction, humans are the poorest performers of all mammals. In fact we are so inefficient that up to 75% of fertilized eggs do not produce live births, and up to 30% of pregnancies end up being lost within 10 weeks of conception (in the…