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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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165 answers

Egg Health & Ovarian Reserve

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Egg Health & Ovarian Reserve Nov 2, 2023

Elevated dhea

I just Received blood work where my dhea levels are elevated and they might believe it’s associate with pcos. What can I do In regards to having a baby? — Julie A.

Dr. Geoffrey Sher answered

Raised DHEA is not a real problem . it is a raised DHEAS that xcouyld be problematic as it would point to a possible adrenal contribution to the PCOS equation. Navigating Polycystic Ovary Syndrome: Understanding, Hope, and Treatment Geoffrey Sher MD Understanding the intricate interplay of hormones and…
Egg Health & Ovarian Reserve Nov 2, 2023

Egg freezing risks in IVF

Hello Dr. Sher I am 39, childless and I'm currently undergoing IVF in Portugal. I have had 4 miscarriages in the past (2 clinical and 2 chemicals). On my last scan, my AFC was 15. My AMH is 1.24. I… — Lisa-Marie E.

Dr. Geoffrey Sher answered

I concur. I would collect as many eggs as possible in advance. "Empowering Choices: Embryo Banking vs. Egg Banking for Fertility Preservation" Geoffrey Sher MD It's crucial for women to make informed decisions about preserving their fertility. Delaying trying to conceive, relying on egg freezing, or assuming the…
Egg Health & Ovarian Reserve Oct 31, 2023

Immature Egg Rate

Good afternoon, For my 1st, and most recent cycle, I retrieved 14 eggs and only 6 were mature. 6 were GV and 2 were M1. I am 32, my AFC was 17, my AMH is 2.4, my CD3 FS &… — Margaret C.

Dr. Geoffrey Sher answered

In my opinion, this is likely due to the protocol used for ovarian stimulation (see below EGG/ EMBRYO QUALITY IN IVF & HOW SELECTION OF THE IDEAL PROTOCOL FOR OVARIAN STIMULATION INFLUENCES EGG/EMBRYO QUALITY AND OUTCOME. Geoffrey Sher MD The journey of in vitro fertilization can be a…
Egg Health & Ovarian Reserve Oct 30, 2023

Reoccurring failed implantation

Hi Dr. Sher, I found your website after researching pgt embryos that fail to implant. I’m 38 years old, I have DOR, AMH .5 when tested a year ago, FSH 10.3. I did three retrievals and ended up with 5… — Jill D.

Dr. Geoffrey Sher answered

Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Egg Health & Ovarian Reserve Oct 26, 2023

IVF

I have gone through two failed IVF cycles and have very low AMH 0.4.. is it possible for me to undergo another IVF with my own eggs — Samudika R.

Dr. Geoffrey Sher answered

Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…
Egg Health & Ovarian Reserve Oct 16, 2023

Empty follicles

Hi Dr, thanks for your article on empty follicles. I have DOR, and had two retrievals in 2021 and 2023 which yielded zero eggs (out of 3-4 follicle ). My protocol were different each time but both at least included… — Halima I.

Dr. Geoffrey Sher answered

It is too complex to respond to here. I suggest you call my assistant Patti at 702-533-2691 and set up an online consultation with me to discuss. Geoff Sher
Egg Health & Ovarian Reserve Oct 13, 2023

DOR

dear Dr.Sher , please help me with your advice. i admire you and i am so sad that here in Serbia we don’t have more fertility options. 39yo ,DOR , fsh 30 , Amh 0,375 4 IVF 1st and 4.… — Ana T.

Dr. Geoffrey Sher answered

Thank you for your kind words Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation…
Egg Health & Ovarian Reserve Oct 9, 2023

Poor Fertilization and Embryo Quality

Hello. I had an egg retrieval last week - 75 eggs collected, 1/2 normal insemination and 1/2 ICSI. 0 eggs fertilized with normal insemination. In the ICSI group (38 eggs) - 25 mature, 12 fertilized, 1 graded 3BB blast at… — Nkoli A.

Dr. Geoffrey Sher answered

I suspect it has to do with the ovarian stimulation protocol rather than an inherent egg quality deficit. Geoff Sher Empowering Choices: Embryo Banking vs. Egg Banking for Fertility Preservation" Geoffrey Sher MD It's crucial for women to make informed decisions about preserving their fertility. Delaying trying to…
Egg Health & Ovarian Reserve Oct 2, 2023

Success at 44

Hello. My husband and I are trying for our first. I am 44. My AMH was assessed 8 months ago and was .09. At the time my FSH was 14. I took a urine sample this cycle and it is… — Sara E.

Dr. Geoffrey Sher answered

IVF at 44y, even with normal ovarian reserve (AMH) is a long shot. See below. Sorry! Geoff Sher ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF Geoffrey Sher MD Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is…
Egg Health & Ovarian Reserve Sep 27, 2023

HGH

Hi Dr. Sher, I’m wondering what your opinion is on using HGH specifically for egg QUALITY (not quantity). I’m turning 44 in a week and although my reserve seems to be fine, it’s the quality that I’m attempting to help.… — Bree M.

Dr. Geoffrey Sher answered

IVF and the use of Supplementary Human Growth Hormone (HGH) : Is it Worth Trying and who needs it? Geoffrey Sher MD Older women and those who have diminished ovarian reserve (DOR) have greater difficulty in conceiving naturally or through assisted reproductive technology (ART). This is largely due…
Egg Health & Ovarian Reserve Sep 20, 2023

Flare Protocol for Low Ovarian Reserve

Hi Dr. Sher, I have gone through 2 ivf cycles and one FET done so far - i had 5 eggs retrieved in first cycle , 4 fert, resulting in 1 euploid embryo . Second cycle - 8 follicles, 6… — Sujana G.

Dr. Geoffrey Sher answered

Women with DOR , often have excessive LH-induced ovarian testosterone production which in my opinion can be hazardous to egg development. Lupron induces a rapid increase in LH release and in the setting of DOR further prejudices egg development. When Lupron is given at the very start of…
Egg Health & Ovarian Reserve Sep 9, 2023

Low AMH

Dear Dr. Sher, I am 36-year-old, planning an IVF in a couple of months, but AMH today shows low 1.01 ng/ml. Do I have good chances? Planning to go through egg pooling, NGS and 1 embryo transfer. I want to… — Ola C.

Dr. Geoffrey Sher answered

Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…
Egg Health & Ovarian Reserve Aug 24, 2023

Fertilizing well, but with really high attrition rates

Age: 39.5 AMH 3.6 FSH 6.1 LH 4.6 I just completed my second fairly disappointing cycle. I've been told my AMH is high for my age, although, I have not been formally diagnosed with PCOS and my RE told me… — Taylor M.

Dr. Geoffrey Sher answered

In my provisional opinion, this is likely attributable to the protocols used for ovarian stimulation. I do not agree with testosterone supplementation or concomitant clomiphene included in the cycle. I think we should talk and I urge you to contact Patti Converse (my assistant) at 702-533-2691 (see below).…
Egg Health & Ovarian Reserve Aug 23, 2023

13 cycles of immature eggs

Dear Dr Sher, I'm 37.5 years old and have a long history of unsuccessful IVF rounds albeit with one successful cycle four years ago. My case has been classed as quite challenging. I've undergone 13 IVF cycles under the care… — O W.

Dr. Geoffrey Sher answered

_ If you've undergone in vitro fertilization (IVF) and didn't achieve a successful pregnancy, you may be wondering why. It's important to know that IVF outcomes can be unpredictable, but there are factors that can affect your chances. Let's explore some common reasons for IVF failure in simpler…
Egg Health & Ovarian Reserve Aug 11, 2023

Failing to achieve an euploid

Dear Dr. Sher, 42 year old here desperately wanting to be mother for the first time! 6 year unknown infertility, 99 lbs, 5'6'', eat healthy, taking COQ10 and prenatal, very healthy and no disease illnesses in the past. My AMH… — Anne C.

Dr. Geoffrey Sher answered

Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

165 answers

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