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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Answers from our doctors

Search 1,006 questions patients have already asked, or narrow them by topic.

  1. Egg Health & Ovarian Reserve

    DOR

    dear Dr.Sher , please help me with your advice. i admire you and i am so sad that here in Serbia we don’t have more fertility options. 39yo ,DOR , fsh 30 , Amh 0,375 4 IVF 1st and 4.… — Ana T.

    Dr. Geoffrey Sher answered

    Thank you for your kind words Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation…

  2. Egg Health & Ovarian Reserve

    Poor Fertilization and Embryo Quality

    Hello. I had an egg retrieval last week - 75 eggs collected, 1/2 normal insemination and 1/2 ICSI. 0 eggs fertilized with normal insemination. In the ICSI group (38 eggs) - 25 mature, 12 fertilized, 1 graded 3BB blast at… — Nkoli A.

    Dr. Geoffrey Sher answered

    I suspect it has to do with the ovarian stimulation protocol rather than an inherent egg quality deficit. Geoff Sher Empowering Choices: Embryo Banking vs. Egg Banking for Fertility Preservation" Geoffrey Sher MD It's crucial for women to make informed decisions about preserving their fertility. Delaying trying to…

  3. Egg Health & Ovarian Reserve

    Success at 44

    Hello. My husband and I are trying for our first. I am 44. My AMH was assessed 8 months ago and was .09. At the time my FSH was 14. I took a urine sample this cycle and it is… — Sara E.

    Dr. Geoffrey Sher answered

    IVF at 44y, even with normal ovarian reserve (AMH) is a long shot. See below. Sorry! Geoff Sher ADDRESSING ADVANCING AGE AND DIMINISHING OVARIAN RESERVE (DOR) IN IVF Geoffrey Sher MD Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is…

  4. Egg Health & Ovarian Reserve

    HGH

    Hi Dr. Sher, I’m wondering what your opinion is on using HGH specifically for egg QUALITY (not quantity). I’m turning 44 in a week and although my reserve seems to be fine, it’s the quality that I’m attempting to help.… — Bree M.

    Dr. Geoffrey Sher answered

    IVF and the use of Supplementary Human Growth Hormone (HGH) : Is it Worth Trying and who needs it? Geoffrey Sher MD Older women and those who have diminished ovarian reserve (DOR) have greater difficulty in conceiving naturally or through assisted reproductive technology (ART). This is largely due…

  5. Egg Health & Ovarian Reserve

    Flare Protocol for Low Ovarian Reserve

    Hi Dr. Sher, I have gone through 2 ivf cycles and one FET done so far - i had 5 eggs retrieved in first cycle , 4 fert, resulting in 1 euploid embryo . Second cycle - 8 follicles, 6… — Sujana G.

    Dr. Geoffrey Sher answered

    Women with DOR , often have excessive LH-induced ovarian testosterone production which in my opinion can be hazardous to egg development. Lupron induces a rapid increase in LH release and in the setting of DOR further prejudices egg development. When Lupron is given at the very start of…

  6. Egg Health & Ovarian Reserve

    Low AMH

    Dear Dr. Sher, I am 36-year-old, planning an IVF in a couple of months, but AMH today shows low 1.01 ng/ml. Do I have good chances? Planning to go through egg pooling, NGS and 1 embryo transfer. I want to… — Ola C.

    Dr. Geoffrey Sher answered

    Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…

  7. Egg Health & Ovarian Reserve

    Fertilizing well, but with really high attrition rates

    Age: 39.5 AMH 3.6 FSH 6.1 LH 4.6 I just completed my second fairly disappointing cycle. I've been told my AMH is high for my age, although, I have not been formally diagnosed with PCOS and my RE told me… — Taylor M.

    Dr. Geoffrey Sher answered

    In my provisional opinion, this is likely attributable to the protocols used for ovarian stimulation. I do not agree with testosterone supplementation or concomitant clomiphene included in the cycle. I think we should talk and I urge you to contact Patti Converse (my assistant) at 702-533-2691 (see below).…

  8. Egg Health & Ovarian Reserve

    13 cycles of immature eggs

    Dear Dr Sher, I'm 37.5 years old and have a long history of unsuccessful IVF rounds albeit with one successful cycle four years ago. My case has been classed as quite challenging. I've undergone 13 IVF cycles under the care… — O W.

    Dr. Geoffrey Sher answered

    _ If you've undergone in vitro fertilization (IVF) and didn't achieve a successful pregnancy, you may be wondering why. It's important to know that IVF outcomes can be unpredictable, but there are factors that can affect your chances. Let's explore some common reasons for IVF failure in simpler…

  9. Egg Health & Ovarian Reserve

    Failing to achieve an euploid

    Dear Dr. Sher, 42 year old here desperately wanting to be mother for the first time! 6 year unknown infertility, 99 lbs, 5'6'', eat healthy, taking COQ10 and prenatal, very healthy and no disease illnesses in the past. My AMH… — Anne C.

    Dr. Geoffrey Sher answered

    Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…

  10. Egg Health & Ovarian Reserve

    PGTA/Endometriosis

    Hi, quick background info- 37 years old, husband is 48 years old. I have stage 4 endometriosis with bilateral endometriomas about 4-5 cm on both ovaries. AMH of 3.8, FSH 5.5, Estradiol 45. Sperm analysis is above normal. I just… — Marie F.

    Dr. Geoffrey Sher answered

    When women with infertility due to endometriosis seek treatment, they are all too often advised to first try ovarian stimulation (ovulation Induction) with intrauterine insemination (IUI) ………as if to say that this would be just as likely to result in a baby as would in vitro fertilization (IVF).…

  11. Egg Health & Ovarian Reserve

    HGH if PCOS suspected?

    Hello I read your blog and love the content. I am 36yrs old woman (AMH 29 pmol/L, AFC 14-20), obesity (BMI from 31-34 in the last year, used to be much more). My DHEA, testosterone, PRL were normal/low-normal/mid-range... FSH 7… — Petra V.

    Dr. Geoffrey Sher answered

    HGH will not do harm. I personally do not advocate routine use of DHEA. The journey of in vitro fertilization can be a rollercoaster of emotions for many patients. Often times they have to face the harsh reality that the number and quality of eggs retrieved has fallen…

  12. Egg Health & Ovarian Reserve

    IVF own eggs after failed attempt

    Hello, I am considering treatment at a new clinic after a disappointing first attempt at IVF. I am 46 years old and tried using my own eggs. From my last blood test some two months ago I had an AMH… — Yasmin V.

    Dr. Geoffrey Sher answered

    You certainly could try again, but please know that age is a major factor affecting IVF outcome. Women over 44y of age are advised to do egg donation. Age should never be a barrier to hope and fulfillment when it comes to IVF. Many women in their early…

  13. Egg Health & Ovarian Reserve

    Fertility and egg rupturing

    My amh is 20 and now I am into iui treatment. My follicle size is 23mm in right ovary and left ovary pcos . My egg is not rupturing after taking injection also.. — Tej K.

    Dr. Geoffrey Sher answered

    I would need much more information to respond informatively! Sorry! GS ADDITIONAL INFORMATION: I am attaching online links to two E-books which I recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: 1.From In Vitro Fertilization to Family: A Journey with Sher Fertility…

  14. Egg Health & Ovarian Reserve

    No blastocysts from 2 ivf cycles.

    My husband and I are both 29 years, we’ve been trying to conceive since two years and we’ve started visiting a fertility clinic since 11/2022. We’re both healthy, have no other health issues. Later in March-2023, my AMH fell to… — Kamala K.

    Dr. Geoffrey Sher answered

    If you've undergone in vitro fertilization (IVF) and didn't achieve a successful pregnancy, you may be wondering why. It's important to know that IVF outcomes can be unpredictable, but there are factors that can affect your chances. Let's explore some common reasons for IVF failure in simpler terms.…

  15. Egg Health & Ovarian Reserve

    CoQ10

    Would love to hear your thoughts on taking CoQ10 in women over 40yrs doing IVF? If you feel it’s worth taking, at what dose & duration pre- IVF, Thanks, R — Rosie S.

    Dr. Geoffrey Sher answered

    It is important to nurture and take care of yourself mentally and physically when preparing and going through your IVF journey. This starts with trying to have a positive attitude about what you are about to go through, creating a stress support system for yourself by using tools…

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