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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Search 1,006 questions patients have already asked, or narrow them by topic.

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  1. Hormones & Ovulation

    estradiol

    Can you kindly tell me what is the appropriate level of estradiol in a modified natural cycle? I am in the middle of a MN cycle. They had me take letrozole for 5 days and roughly 10 days later I… — Carmela R.

    Dr. Geoffrey Sher answered

    Each follicle should contribute 150-200pg/ml to the E2 level. Your dropping E2 is concerning and suggests premature luteinization. I think when this cycle is over we should talk. The protocol used for ovarian stimulation and its implementation are both pivotal. Call my assistant, Patti at 702-533-2691 and set…

  2. Ovarian Stimulation & OHSS

    IUD/Egg Retrieval

    Hello! I’m interested in getting an IUD and freezing my eggs. I’d like to do the IUD insertion while under anesthetia for egg retrieval. Is that possible? Thanks! Isabella — Isabella G.

    Dr. Geoffrey Sher answered

    WE can help! Please call us and ask for Dr Ravikumar.

  3. Embryos & Genetic Testing

    Recurrent Failed implantation

    H! Dr. Sher , I am honored to have a chance to ask you some questions about IVF . My husband and I just had a failed embryo transfer which was our 4th transfer with a euploid embryo and all… — Maria P.

    Dr. Geoffrey Sher answered

    Thank you for your communication. Below please find information that I feel confident will help explain the possible reasons for implantation dysfunction. Thereupon, if you would like to have a consultation with me to discuss your circumstances and potential remedies, please call or text my assistant, Patti Converse…

  4. Immunology & Implantation

    covid

    Hi, Dr Sher I got COVID 1 day prior to FET My FET was cancelled They say I can proceed next cycle. Do you agree that next cycle we can proceed or should be a longer washout period to allow… — Carmela R.

    Dr. Geoffrey Sher answered

    I agree with the advice given by your doctor! Good luck! Geoff Sher

  5. Immunology & Implantation

    implantation dysfunction

    Listened to you on a podcast recently and appreciate you so much for sharing your knowledge on this topic. Wondering if you have any input for next steps after 2 implantation failures (of 5AA embryos without PGT-A testing, female age… — Ashley S.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

  6. Embryos & Genetic Testing

    Repeat failed implantations

    I have experienced one miscarriage and four failed implantations with untested embryos. In my recent IVF cycle, I obtained one PGT-A–tested 5AB euploid embryo. I also underwent a hysteroscopy with a uterine biopsy to investigate the failed implantations, and all… — Fab W.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

  7. Hormones & Ovulation

    FET

    Hello! I had a recent FET just a few days ago. On the day oftransfer, my progesterone was 37 and estradiol was 1700. This estradiol level is considerably higher than it was for my last successful FET. So I am… — Eugenia T.

    Dr. Geoffrey Sher answered

    The E2 level, ideally, should be 500-100pg/ml on the day progesterone treatment starts. Endometrial thickness is measured also on the day progesterone starts. It needs to be >8mm with a trilaminar ultrsound appearance, The thickness on the day of transfer is not significant. See the article below, on…

  8. Embryos & Genetic Testing

    Dup(13)(q21.1-qter)[mos]

    DI have a high level mosaic Dup(13)(q21.1-qter)[mos] tested by Cooper. My doctor had incureged me to transfer but genetic councilor seemed concerned. What do you think? — Veselina M.

    Dr. Geoffrey Sher answered

    I agree with your doctor unless there is a pressing reason to 1st do another cycle using a modified/improved protocol for ovarian stimulation to try and access more euploid embryos for use. Geoff Sher Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY…

  9. IVF Failure & Pregnancy Loss

    Implantation failure regarding

    Hello Doctor, I have a query regarding repeated implantation failure. I have low amh and my spouse has severe Oligoasthenoteratozoospermia(only 2 sperm found even under the highest resolution). So we opted for donor eggs and donor sperms. But overall I… — Shilpa M.

    Dr. Geoffrey Sher answered

    IMPLANTATION DYSFUNCTION Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors.…

  10. Embryos & Genetic Testing

    Testing

    I have a history of-two failed FET Embryos were not tested Embryos were not tested at 37 years old. I did two more rounds of IVF and I have now 7 euploids with CCRM I also did a lap to… — Michelle F.

    Dr. Geoffrey Sher answered

    They are wrong with regard to the Receptiva test. It is very helpful in diagnosing silent endometriosis which if present can be associated with an immunologic implantation dysfunction (IID) I am not a believer in Emma/Alice testing and ; The method of FET will not affect the risk…

  11. Early Pregnancy & hCG

    First pregnancy scan after IVF with PGT

    Hi, I've recently discovered I'm pregnant through IVF with an euploid embryo. I had my first beta HCG blood test at 12 days past transfer and this came back at 540 IU/L. I'm now waiting for my first scan in… — Mary D.

    Dr. Geoffrey Sher answered

    Congratulations!! I wish I could predict. Unfortunately you will need to wait for the US result! Good luck! Geoff Sher

  12. Embryos & Genetic Testing

    Blighted Ovum

    I just had my first FET, and it resulted in a blighted ovum. I am 35 years old with 5 PGT abnormal eggs. We will try again in a few months. But in the meantime, is there anything I should… — Kate S.

    Dr. Geoffrey Sher answered

    I would need much more information to provide an authoritative opinion. Feel free to contact my assistant, Patti (concierge@sherivf.com to set up an online consultation with me. to discuss. Geoffrey Sher MD ADDITIONAL INFORMATION: Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY…

  13. Clinic & Practice

    IVF second opinion

    I need a second opinion. I am 35 years old on my first round of IVF after 2 failed IUIs. I have been trying for a year to get pregnant. I have AMH level of .112 and 7 follicles. This… — Gweneth V.

    Dr. Geoffrey Sher answered

    Thank you for reaching out. I will do my best to help: Given your diminished ovarian reserve; IUI is definitely not for you. The success rate is far too low and you do not have the time to spare. You do need IVF but unless an individualized protocol…

  14. Fertility Preservation

    Egg freezing

    Hello there I need some information I’m from Texas wanting to do egg freezing looking for bowl part of course No insurance I saw someone on TikTok talking about your clinic so wanted to get lucky I’m 42 my AMH… — Mona R.

    Dr. Geoffrey Sher answered

    For more than 50 years, scientists have been working to perfect the art of freezing and storing a woman's eggs, also known as “egg banking”. Although there have been challenges, the progress has been both amazing and is promising. Since the birth of the first "frozen egg baby"…

  15. Egg Health & Ovarian Reserve

    Stimulation protocols for DOR in 45 yr old

    I'm trying to write up the protocol outlined in one of your recent videos with the egg whisper to take to my Dr. whom is going to do my next cycle. We've started the HGH and we did the PRP… — Ariane B.

    Dr. Geoffrey Sher answered

    I would never presume tom tell your doctor what to do with regard to your stimulation. I can tell you that regardless of protocol, the chance of propagating euploid ("competent") eggs at 45y is very slim (!:2o eggs or so will end up being viable). Obviously if in…

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