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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Answers from our doctors

Search 1,010 questions patients have already asked, or narrow them by topic.

Latest answers

Page 4 of 68

  1. Age & Fertility

    Reoccurring GeneticRisk

    I am turning 41 in a couple weeks and unfortunately just had to make the heart wrenching choice to medically terminate our Trisomy 21 pregnancy at 13 weeks. Two years ago, I had a miscarriage/ D&C due to Trisomy 10.… — Kim S.

    Dr. Geoffrey Sher answered

    The cause of your trisomy pregnancy was likely age-related egg aneuploidy. The chance of an embryo having the right chromosomal configuration declines with with advancing age. Since you already have several children, you might want to stop. However, since you et pregnant quite easily on your own, and…

  2. Immunology & Implantation

    Reproductive Immunology

    Hello, I have had two, late, second trimester losses, back to back. Both of these losses have happened since I was diagnosed with a rare autoimmune, eosinophillic esophagitis. What is your familiarity with reproductive immunology and how likely is there… — Kathryn C.

    Dr. Geoffrey Sher answered

    In the world of assisted reproduction, when IVF fails repeatedly or without explanation, it's often assumed that poor embryo quality is the main culprit. However, this view oversimplifies the situation. The process of embryo implantation, which begins about six or seven days after fertilization, involves a complex interaction…

  3. Hormones & Ovulation

    High testosterone during hormone suppression prior to fet

    Hi I am currently doing suppression before embryo transfer. I am almost 2 month into suppression with lupron depot, letrozole, and norethindrone. I had done 2 months of suppression with just lupron about 6 months ago before a transfer that… — Holly F.

    Dr. Geoffrey Sher answered

    A high testosterone has an adverse effect on egg/embryo quality and endometriosis can adversely affect embryo attachment (implantation) through an immune mechanism. Feel free to email my assistant, Patti (concierge@sherivf.com if you wish to discuss your case with me online. Geoff Sher

  4. Ovarian Stimulation & OHSS

    DOR,age,IVF

    Hello, dear doctor. Listened to you podcast and been blown away by your expertise! I am a youthful 45 year old trying to get pregnant. Gotten pregnant 2 years ago naturally, but miscarried in week 9. Had done 3 IVF… — Maja S.

    Dr. Geoffrey Sher answered

    Understanding the impact of age and ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it comes to reproductive health. This article aims to simplify and clarify these concepts, emphasizing their significance in the selection of ovarian stimulation protocols for IVF. By providing you…

  5. Early Pregnancy & hCG

    Heavy bleeding after possible implantations

    Hi, I've had two egg collections resulting in 5 embryos (3 of which didn't survive thawing) and 3 on the second round. In my first fresh embryo transfer I passed a couple of large blood clots the day after transfer,… — Megan M.

    Dr. Geoffrey Sher answered

    IMPLANTATION DYSFUNCTION Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors.…

  6. Ovarian Stimulation & OHSS

    4th IVF cycle questions on microdose flare protocol

    Hello Dr. Sher, I am 42 yrs old with a low AMH (less than 1) trying to get pregnant for the 2nd time. My first pregnancy was natural when I was 38. I started my 2nd fertility journey with IUI… — Terri M.

    Dr. Geoffrey Sher answered

    At 42 years of age and especially if you are experiencing diminishing ovarian reserve, a flare protocol (in my opinion) is less than ideal. I suggest you call my assistant, Patti at 702-533-2691 and set up an online consultation with me. Geoff Sher EGG/ EMBRYO QUALITY IN IVF…

  7. Hormones & Ovulation

    estradiol

    Can you kindly tell me what is the appropriate level of estradiol in a modified natural cycle? I am in the middle of a MN cycle. They had me take letrozole for 5 days and roughly 10 days later I… — Carmela R.

    Dr. Geoffrey Sher answered

    Each follicle should contribute 150-200pg/ml to the E2 level. Your dropping E2 is concerning and suggests premature luteinization. I think when this cycle is over we should talk. The protocol used for ovarian stimulation and its implementation are both pivotal. Call my assistant, Patti at 702-533-2691 and set…

  8. Ovarian Stimulation & OHSS

    IUD/Egg Retrieval

    Hello! I’m interested in getting an IUD and freezing my eggs. I’d like to do the IUD insertion while under anesthetia for egg retrieval. Is that possible? Thanks! Isabella — Isabella G.

    Dr. Geoffrey Sher answered

    WE can help! Please call us and ask for Dr Ravikumar.

  9. Embryos & Genetic Testing

    Embryo

    Hello- I’m looking to discuss possible embryo creation. does your practice take insurance? — Tatiane T.

    Dr. Drew Tortoriello answered

    Yes we do take insurance. Please call my assistant, Patti at 702-533-2691

  10. Embryos & Genetic Testing

    Recurrent Failed implantation

    H! Dr. Sher , I am honored to have a chance to ask you some questions about IVF . My husband and I just had a failed embryo transfer which was our 4th transfer with a euploid embryo and all… — Maria P.

    Dr. Geoffrey Sher answered

    Thank you for your communication. Below please find information that I feel confident will help explain the possible reasons for implantation dysfunction. Thereupon, if you would like to have a consultation with me to discuss your circumstances and potential remedies, please call or text my assistant, Patti Converse…

  11. Immunology & Implantation

    covid

    Hi, Dr Sher I got COVID 1 day prior to FET My FET was cancelled They say I can proceed next cycle. Do you agree that next cycle we can proceed or should be a longer washout period to allow… — Carmela R.

    Dr. Geoffrey Sher answered

    I agree with the advice given by your doctor! Good luck! Geoff Sher

  12. Immunology & Implantation

    implantation dysfunction

    Listened to you on a podcast recently and appreciate you so much for sharing your knowledge on this topic. Wondering if you have any input for next steps after 2 implantation failures (of 5AA embryos without PGT-A testing, female age… — Ashley S.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

  13. Embryos & Genetic Testing

    Repeat failed implantations

    I have experienced one miscarriage and four failed implantations with untested embryos. In my recent IVF cycle, I obtained one PGT-A–tested 5AB euploid embryo. I also underwent a hysteroscopy with a uterine biopsy to investigate the failed implantations, and all… — Fab W.

    Dr. Geoffrey Sher answered

    Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…

  14. Embryos & Genetic Testing

    Second transfer

    Hello!! I wanted to inquire about a possible timeline for a second embryo transfer. My daughter was born via c section 11/19/24. We have been trying to conceive since January of this year. When would be an appropriate time to… — Samantha L.

    Dr. Drew Tortoriello answered

    Any cycle would be fine! FROZEN EMBRYO TRANSFER : ONE PREFERRED APPROACH AT SFS. Two decades ago, when women went through IVF (in vitro fertilization), they usually had their embryos put in the uterus right after the eggs were collected in the same cycle (known as "Fresh" Embryo…

  15. Third-Party Reproduction

    GC

    Hello. I am a 2x GC. I had my 6th delivery this year and was wondering if I was able to use this clinic for my next transfer? I have never had any complications with pregnancy or delivery. Please let… — Britanny T.

    Dr. Drew Tortoriello answered

    I do not see this as a problem! Geoff Sher Creating Families through IVF Surrogacy: A Journey of Hope” IVF surrogacy is a remarkable process that allows individuals and couples to fulfill their dreams of parenthood, offering a path to hope and happiness. Let’s explore this transformative journey,…

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