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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Embryos & Genetic Testing Mar 9, 2026

Recurrent Natural Pregnancy Loss followed by Recurrent Implantation Failure

I (33 years old) have a small piece of "benign" genetic material (#15) mosaically which may be contributing to recurrent natural pregnancy loss (4 losses, 2 were between 10-16 weeks with confirmed T18 and T21). Genetic Counselors could not confirm… — Sam L.

Dr. Geoffrey Sher answered

WE really need to talk. I invite you to contact my Office Manager, Patti Converse (702-533-2691 and set up an online consultation with me. UNDERSTANDING RECURRENT PREGNANCY LOSS ( RPL): CAUSES AND SOLUTIONS. When it comes to reproduction, humans face challenges compared to other mammals. A significant number…
Embryos & Genetic Testing Mar 2, 2026

Potential transfer of aneuploid embryos with your clinic?

Hello, I had two failed transfers with my euploid and mosaic embryos. I have two aneuploid embryos left and we're considering transferring to your clinic for transfer if they would be considered. My clinic won't transfer aneuploids and I've read… — Sarah P.

Dr. Geoffrey Sher answered

HONESTLY, i DO NOT RECOMMEND TRANSFECTING ANEUPLOID EMBRYOS. SORRY! GEOFF SHER
Immunology & Implantation Feb 13, 2026

Hashimoto-NK toxicity

Dear Dr. Sher, I have a diagnosed Hashimoto‘s disease with high thyroid antibodies >1500. We tried naturally for a while but nothing happend. I am 33 and my husband is 34 yeras old. I recently tested my NK cell acitivation… — Anna G.

Dr. Geoffrey Sher answered

Between 2% and 5% of women of the childbearing age have reduced thyroid hormone activity (hypothyroidism). Women with hypothyroidism often manifest with reproductive failure i.e. infertility, unexplained (often repeated) IVF failure, or recurrent pregnancy loss. The condition is 5-10 times more common in women than in men. In…
Male Infertility Jan 21, 2026

Sperm

How do I go about it — Jaheim W.

Dr. Geoffrey Sher answered

Please email my office Manager Patti Converse at concierge@sherIVF.com and set up an onlne consultation with me. Geoff Sher
Clinic & Practice Jan 21, 2026

Ovarian mass

I would like a consultation — Swandi C.

Dr. Geoffrey Sher answered

Please email my office Manager Patti Converse at concierge@sherIVF.com and set up an onlne consultation with me. Geoff Sher
Ovarian Stimulation & OHSS Jan 21, 2026

Protocols

Wanted to chate about my protocols.. — Sabrina K.

Dr. Geoffrey Sher answered

I suggest you email Patti at concierge@sherivf.com and set up an online consultation with me. Geoff Sher
Embryos & Genetic Testing Jan 21, 2026

Recurrent Pregnancy Loss

I have a history of autoimmune and clotting issues possibly contributing to recurrent pregnancy loss (4 losses, 2 from IVF) and currently have 6 frozen PGT-A tested embryos at Shady Grove Fertility (4 euploid, 2 mosaic). I no longer have… — Katie B.

Dr. Geoffrey Sher answered

UNDERSTANDING RECURRENT PREGNANCY LOSS ( RPL): CAUSES AND SOLUTIONS. When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending…
Clinic & Practice Jan 21, 2026

Question

We wanna to know how much consultation it's cost — Irina G.

Dr. Geoffrey Sher answered

Please call my office Manager, Patti at 702-533-2691 and inquire with her. Geoff Sher
Embryos & Genetic Testing Jan 21, 2026

EMBRYO

Hello Dr. Sher, I have 2 embryos frozen in 2021. I am now looking to implant. Embryo 1: - Gardner Score: BG3CB - KIDScore: 4.6 - NGS: Euploid Embryo 2: - Gardner Score: BG4AA - KIDScore: 9.3 - NGS: Low… — Anu A.

Dr. Geoffrey Sher answered

The euploid embryo!
Uterine & Endometrial Health Jan 21, 2026

Endometriosis

Dr. Sher, I successfully cycled with you in April 2004 in the NYC office. I also gave birth to another child naturally (miraculously after an ectopic 6 months after I had my child through IVF). My second child is now… — Sara N.

Dr. Geoffrey Sher answered

Please have her reach out to my Office Manager, Patti Converse (conciege@sherivf.com and set up a consultation online, with me. Geoff Sher ENDOMETRIOSIS: A RATIONAL BASIS FOR IVF Endometriosis is a condition where the uterine lining (endometrium) grows on pelvic structures outside the uterine cavity. In early stage-…
Egg Health & Ovarian Reserve Jan 21, 2026

Research papers on trigger dosage for POI/DOR patients

Dear Dr. Sher, with great interest have I read your articles on the "empty" follicle syndrome: I was diagnosed with premature ovarian insufficiency incl. elevated LH levels. In my two egg retrieval attempts only 1 egg could be retrieved out… — Lena T.

Dr. Geoffrey Sher answered

I suggest you email Patti Converse (concierge@sherivf.com and set up an online consultation with me. Geoff Sher
Uterine & Endometrial Health Jan 21, 2026

ERA testing

Dr. Geoffrey Sher answered

i PERSONALLY AM NOT A BIG BELIEVER IN THE VALUE OF ERA TESTING. GEOFF SHER
Infertility Basics Jan 21, 2026

unexplained infertility age 33

I have unexplained infertility, age 33, partner 29. We have done all the testing(HSG,bloodwork,ultrasounds) and everything looks very normal. AMH 1.1 (which I’ve been told is a little low for my age but still normal). We have tried for 1.5… — Nour N.

Dr. Geoffrey Sher answered

UNEXPLAINED” INFERTILITY: A RATIONAL APPROACH TO MANAGEMENT Infertility affects y 10%-15% of couples who are unable to conceive. In some cases, the cause of infertility cannot be determined using conventional diagnostic methods, leading to a diagnosis of "unexplained infertility." However, it is important to note that in most…
Ovarian Stimulation & OHSS Jan 21, 2026

Fresh or frozen transfer

I’m currently on a short antagonist with a fresh cycle, following my egg retrieval the doctor noted she could see triple layer endometrium but there was no triple layer detected in the most recent scan so mentioned as she didn’t… — Louise S.

Dr. Geoffrey Sher answered

Yes you can go ahead. However, please be aware that 30% of women with endometriosis (regardless of severity, havd an immunologic implantation dysfunction (see below) which needs treatment. Geoff Sher Contact my Office manager..for appointment: Concierge@sherivf.com ENDOMETRIOSIS AND IMMUNOLOGIC IMPLANTATION FAILURE. Patients with endometriosis have immunologic abnormalities. The…
Ovarian Stimulation & OHSS Nov 14, 2025

Agonist/Antagonist Conversion protocol-meds

Hello Dr. Sher. I have a question about the Agonist/Antagonist Conversion protocol I am to start this protocol, and I wonder if it matters if I use Menopur or Gonal-F/Follistim during the stimulation? The reason for this question is that… — Liz S.

Dr. Geoffrey Sher answered

Embarking on the journey of in vitro fertilization (IVF) can be a daunting experience especially for women with sub-normal AMH levels (diminished ovarian reserve -DOR). Here is a novel and highly effective protocol known as the Agonist/Antagonist Conversion Protocol (A/ACP), designed to optimize the chances of success for…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Latest answers

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