– Geoffrey Sher, MD
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Embryos & Genetic Testing
Hi Dr. Sher, You did my egg retrieval 3 years ago, and we welcomed our beautiful daughter 2 years ago. We just did another transfer of 1 pgt embryo for a baby boy, and it failed. We only have 1… — Megan L.
Dr. Geoffrey Sher answered
We should talk. Please call my assistant, Patti (702-533-2691) and set up an online consultation to discuss. Geoff Sher
Immunology & Implantation
Hi Dr. Sher, I live in Toronto and have had 2 chemicals and one miscarriage within the span of 5 months. I used Letrozole to ovulate with the first 2 pregnancies, but I ovulated naturally with the third pregnancy. For… — Catherine B.
Dr. Geoffrey Sher answered
Based upon your representation, this sounds very suggestive of an embryo implantation dysfunction.However, to provide an authoritative opinion we should talk. If I turn out to be correct and you are not treated appropriately to counter the implantation dysfunction, you will very likely experience the same over and…
Immunology & Implantation
Dear Dr Sher I’m 50 year old , I have healthy 9 year old boy from my first marriage, with my second marriage my husband is 55 yrs old , tried one cycle ivf with 2 healthy embryos-my won eggs-… — Fofo A.
Dr. Geoffrey Sher answered
This sounds like a possible implantation dysfunction. I suggest we talk. Please contact my assistant, Patti Converse (702-533-2691) and set up an online consultation with me to discuss in depth. IVF FAILURE WITH “NORMAL” EMBRYOS: EXAMINING AND ADDRESSING ANATOMICAL AND IMMUNOLOGIC CAUSES. Implantation dysfunction is often overlooked as…
Hormones & Ovulation
Hi, My husband and I have been trying to conceive for 2 years now and have had 6 miscarriages within that time, all being early miscarriages except for our little girl who stopped growing at 13 weeks due to triploidy.… — Breann W.
Dr. Geoffrey Sher answered
_ When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent…
IVF Failure & Pregnancy Loss
Hi, I'm 38 yo and I live in Norway, and here the doctors are quite conservative. I have had 5 miscarriages after natural conception. 1 at 5w, then had my son in 2021, then 4 the last 12m, one at… — Helene N.
Dr. Geoffrey Sher answered
When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
Early Pregnancy & hCG
Hello doctor, I had a chemical pregnancy due to low hcg 4yr back …it took a lot of time after that to get pregnant again I had all the basic test that my fertility specialist did and I got pregnant… — Ammy K.
Dr. Geoffrey Sher answered
When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
Embryos & Genetic Testing
I just found out my first FET with a PGT-A tested 6AA embryo is ending in a chemical. I'm 35 with 2 known autoimmune issues (vitiligo and Reynaud's) and a history of RPL (2 miscarriages, at 7 and 8 weeks).… — Jillian B.
Dr. Geoffrey Sher answered
When it comes to reproduction, humans face challenges compared to other mammals. A significant number of fertilized eggs in humans do not result in live births, with up to 75% failing to develop, and around 30% of pregnancies ending within the first 10 weeks (first trimester). Recurrent pregnancy…
Egg Health & Ovarian Reserve
Hi Dr. Sher, I come from Denmark and here we can't screen our embryos - so we transfer untested. I have had all initial testing done in August last year before starting my egg retrievals and all my tests were… — Julie R.
Dr. Geoffrey Sher answered
Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Embryos & Genetic Testing
Hi! I recently had 3 failed iuis and two failed transfers with seemly healthy embryos (BA BB) These eggs were from when I froze them at age 34. I am now 40 and have no embryos left. I have had… — Carolyn S.
Dr. Geoffrey Sher answered
IVF FAILURE WITH “NORMAL” EMBRYOS: EXAMINING AND ADDRESSING ANATOMICAL AND IMMUNOLOGIC CAUSES. Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as…
Early Pregnancy & hCG
I happened to take a test and it was positive i started having pains and irregular spotting i consulted with the health providers and so far i recieved to opinion the first Dr suspected an ealry pregnancy as he could… — Philisiwe P.
Dr. Geoffrey Sher answered
There is no specific hCG level that differentiated between and IUP and an ectopic. However, the level should double every 2 days with normal intrauterine pregnancy ...in the early stage of pregnancy. If it rises more slowly, that suggests a possible failing pregnancy or an ectopic. An US…
IVF Failure & Pregnancy Loss
Hello, I recently had an ET resulting in ectopic pregnancy. I would like to have your opinion on whether this is frequent and in which cases. Thanks — Elia F.
Dr. Geoffrey Sher answered
ECTOPIC (“TUBAL”) PREGNANCY By definition, an ectopic pregnancy is a gestation that occurs outside of the uterine cavity. The most common site is in the fallopian tube, but sometimes it can also occur in the ovary, the cervix, or even the abdominal cavity. Estimates put the incidence of…
IVF Failure & Pregnancy Loss
Me realize una transferencia de embrión con pruebas genéticas preimplantation ales me pusieron intralipidos unas días antes de la transferencia la implantación fue un éxito y todo iba perfecto hasta la semana 6 y 3 días empecé a sangrar fui… — Casandra E.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew Tortoriello MD)....... for your reading pleasure: From In Vitro Fertilization to Family: A Journey with Sher Fertility…
Egg Health & Ovarian Reserve
Dear Dr Sher Geoffrey, I have been through 5 failed IVF rounds. Most of the time my eggs are degenerative, empty or abnormal. I have a 2 year old daughter, concieved naturally, only in 2 months of trying. Now I… — Mary V.
Dr. Geoffrey Sher answered
Hi Sherella; I really think I can help you sort all this out.m However, to do so we would need to consult. I invite you to call my assistant, Patti Converse at 702-53302691 and set up an online consultation with me. ADDRESSING DIMINISHING OVARIAN RESERVE (DOR) IN IVF…
Immunology & Implantation
Hi Dr Sher, I've been getting mixed advice from consultants and I'm hoping you can help. I'm 40years old and have one child, conceived with no issues, and have had a number of chemical pregnancy losses. I'm conceiving very easily,… — Bronagh M.
Dr. Geoffrey Sher answered
Thanks for the inquiry. I think I can help here. Might I suggest that you contact my assistant Patti Converse at 702-533-2691 and set up an online consultation with me to discuss in depth. Geoff Sher When it comes to reproduction, humans face challenges compared to other mammals.…
Embryos & Genetic Testing
Hello Dr. Sher, I listen to your podcast with Dr. Aimee Eyvazzadeh and I wanted to engage with you before going into another FET w/egg donor my questions to you: 5 year IVF Journey/History: * Zero pregnancy * 2 Aneuploid… — Rosalyn G.
Dr. Geoffrey Sher answered
Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
