– Geoffrey Sher, MD
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Age & Fertility
I want to do IVF for triplets but I’m 50+. I’m still seeing my circle but this April, it came out one day and stopped — Chinwe O.
Dr. Geoffrey Sher answered
Given the natural and inevitable decline in "egg competency and ovarian reserve with advancing age, the chance of conceiving on your own or through IVF with own eggs is remote. So sorry! Geoff Sher
Early Pregnancy & hCG
Hello doctor, I spoke with your office, and I understand that you do not follow women's hormones throughout pregnancy. You help women get pregnant and then pass them to an OB. I'm working with a high-risk OB, but because I… — Anna L.
Dr. Drew Tortoriello answered
With very few exceptions. I am not a believer in their being any benefit through progesterone supplementation throughout pregnancy. Geoff Sher
Third-Party Reproduction
como puedo hacer para ser donante de ovulos — Barbara A.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
Ovarian Stimulation & OHSS
I am writing to ask for advice on the proper protocol for me. Background: I am 32 years old, with a normal BMI. My AMH is 0.11, and my AFC is 3. My husband has male-factor infertility that requires IVF.… — Avery C.
Dr. Geoffrey Sher answered
Respectfully, I do not think you were on optimal stimulation protocols. I suggest you call my assistant, Patti (702-533-2691)and set up an online consultation with me to discuss in detail. Understanding the impact of ovarian reserve on the success of in vitro fertilization (IVF) is crucial when it…
Embryos & Genetic Testing
Hello Dr. Sher, I listen to your podcast with Dr. Aimee Eyvazzadeh and I wanted to engage with you before going into another FET w/egg donor my questions to you: 5 year IVF Journey/History: * Zero pregnancy * 2 Aneuploid… — Rosalyn G.
Dr. Geoffrey Sher answered
Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as endo-uterine surface lesions, thin uterine lining (endometrium), or immunological factors. IVF success…
Third-Party Reproduction
Como puedo ser madre surrogada — Sandra A.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
Embryos & Genetic Testing
Hi!! I have a grade 422 low level mosaic. Specifically, it says 46, XY, -Yp (x0, mos, ~40%), -14 (x1, mos, ~50%). What are my real options to have a healthy/sick baby if I get it transferred? Thank you so… — Xiomara R.
Dr. Geoffrey Sher answered
Human embryo development is a marvel of intricate processes, including reprogramming, sequential cleavage divisions, mitotic chromosome segregation, and embryonic genome activation. However, the journey towards a successful pregnancy is not without its challenges, as chromosomal abnormalities can occur during germ cell and preimplantation embryo development, leading to early…
Third-Party Reproduction
Quiero saber cuáles son los requirimientos ya que estoy muy interesada. — Brenda B.
Dr. Drew Tortoriello answered
Please re-post in English! Geoff Sher
Egg Health & Ovarian Reserve
Dear Dr. Geoffrey, I get a empty follicle. What I can change for my last stimulation? Low AMH. Age 40. Kind regards, Charlene — Charlene T.
Dr. Geoffrey Sher answered
“Empty Follicle Syndrome" is a misleading term because follicles always contain eggs. However, some eggs may have difficulties detaching and being retrieved. This is more likely to happen when multiple attempts are needed to retrieve an egg from a follicle, indicating the egg may have chromosomal abnormalities. The…
Ovarian Stimulation & OHSS
Puedo volver a tomar clomid ahora que han pasado más de cuatro meses de descanso? — Iman D.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
Third-Party Reproduction
Cómo hago para ser donante de óvulos que requisitos debo cumplir para donar — Netzaly P.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
Hormones & Ovulation
Dear Dr, my husband and I have a 5year old daughter. we have been trying to get pregnant for the last 4 years but no success so far. we visited a fertility Dr and were subjected to hormonal profile test,… — Clare A.
Dr. Geoffrey Sher answered
UNEXPLAINED” INFERTILITY: A RATIONAL APPROACH TO MANAGEMENT Infertility affects y 10%-15% of couples who are unable to conceive. In some cases, the cause of infertility cannot be determined using conventional diagnostic methods, leading to a diagnosis of "unexplained infertility." However, it is important to note that in most…
Third-Party Reproduction
hola, buen día. Quería saber cuantos años tengo que tener para donar óvulos y cómo sería todo el proceso, tengo que pagar algo? — Brenda N.
Dr. Geoffrey Sher answered
Please re-post in English! Geoff Sher
Cost & Insurance
Hi, My wife and I are doing IVF in Canada and going to transfer embryos to United States for surrogacy. Can I know the cost estimation of FET at your clinic? (including fees to receive embryos from other clinics, FDA… — Ziyi W.
Dr. Geoffrey Sher answered
Please call Jessie at SFS in New York (646-792-7476) for this information. Geoff Sher
Embryos & Genetic Testing
Hello, I compared the markers of different HLA genes between myself and my husband from our raw genetic data which was produced by 23andMe and I found the following: 1. HLA-A: 3/3 markers matched = 100% 2. HLA-B: 2/4 markers… — Holly S.
Dr. Geoffrey Sher answered
This is too complex for me to respond to authoritatively here. I request that you call my assistant, Patti Converse (702-533-2691) and set up an online consultation with me to discuss. Geoff Sher
