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Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

Dear Patients,

I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

– Geoffrey Sher, MD

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Dr. Geoffrey Sher

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Embryos & Genetic Testing Jul 5, 2024

Mosaic 20p embrio

Dear Dr. Sher, We have only one embrio with following NGS data: seq[GRCh37] (20p13p11.21)x1[0.27],(X,Y)x1 Would you please tell, how much are the risks in the case of transfer? Thank you — Alex B.

Dr. Geoffrey Sher answered

In my opinion, it is worth transferring BUT ...if/once pregnant, you should do a CVS or amniocentesis to assess the pregnancy. Decoding Embryo Mosaicism: Navigating the Complex Path to Healthy Births\ Human embryo development is a marvel of intricate processes, including reprogramming, sequential cleavage divisions, mitotic chromosome segregation,…
Uterine & Endometrial Health Jul 5, 2024

Itsmocele

Buenas noches, me han descubierto un itsmocele no muy grande... (creo). Lo malo es q esta a menos de 2mm de la pared vaginal y utero (no estoy muy segura si es asi). La cuestión es que no quieren operarme… — María D.

Dr. Geoffrey Sher answered

Please re-post in English and I will gladly respond! Geoff Sher
Immunology & Implantation Jul 1, 2024

Suggestions before another fet transfer

Hello Dr. Sher, As background, We have been trying to conceive naturally for 2 years. We failed 2 ivf transfers ( both times Fet transfers with confirmed viable euploid blastocysts. 1st transfer was a double blastocyst transfer which's resulted in… — Ben U.

Dr. Geoffrey Sher answered

It certainly sounds as if you do have an implantation dysfunction. However, in my opinion these tests done are not adequate. I suggest you contact Patti Converse (my assistant) at 702-533-2691 and set up an online consultation with me to discuss in detail. Geoff Sher IVF FAILURE WITH…
Immunology & Implantation Jul 1, 2024

Kir y hla

Buenas tardes, nuestro caso mi mujer es kir A/B y c1/c2 mientras yo soy c2c2. Hemos tenido 5 fiv con dgp las dos ultimas, pruebas de trombofilias bien, biopsia endometrial bien y esperma bien. Me gustaria saber si existe en… — Cristian O.

Dr. Geoffrey Sher answered

Please re-post in English! Geoff Sher
Third-Party Reproduction Jul 1, 2024

Donor

Can my daughter donate an egg for ivf — Indira B.

Dr. Geoffrey Sher answered

Yes! Feel free to contact my assistant, Patti Converse at 702-533-2691 to set up an online consultation with me to discuss. Geoff Sher PLEASE SHARE THIS WITH OTHERS AND HELP SPREAD THE WORD!! Herewith are online links to 2 E-books recently co-authored with my partner at SFS-NY (Drew…
Immunology & Implantation Jun 26, 2024

HLA-DQA complete match

Hi Dr Sher I am looking for any supportive data for the claim that complete HLA-DQA matching is impossible to treat with immune therapy. Can you help? Thanks Gavin — Gavin S.

Dr. Geoffrey Sher answered

Unless there is a concomitant NK cell activation, a DQ alpha match is in my opinion irrelevant and no treatment is required. There has to be both NKa+ a match. This is regardless of whether iot is a "partial" or a complete match. A partial match is treatable…
Third-Party Reproduction Jun 24, 2024

Mujer

Quisiera información de cómo es el procedimiento para donar óvulos y si aplico — Gabriela A.

Dr. Geoffrey Sher answered

Please re-post in English! Geoff Sher
Embryos & Genetic Testing Jun 24, 2024

Two failed IVF with healthy embryos

Hi! I recently had 3 failed iuis and two failed transfers with seemly healthy embryos (BA BB) These eggs were from when I froze them at age 34. I am now 40 and have no embryos left. I have had… — Carolyn S.

Dr. Geoffrey Sher answered

IVF FAILURE WITH “NORMAL” EMBRYOS: EXAMINING AND ADDRESSING ANATOMICAL AND IMMUNOLOGIC CAUSES. Implantation dysfunction is often overlooked as a significant reason for IVF failure. This is especially true when IVF failure is unexplained, or when there are recurring pregnancy losses or underlying issues with the uterus, such as…
Early Pregnancy & hCG Jun 24, 2024

Test Interpretation

Hi there, I am just wondering that, if the value of beta HCG is 2029.35 mIU/mL, then what should be the interpretation, means how many weeks pregnancy is this? — Ali R.

Dr. Geoffrey Sher answered

Not possible to date..but on the face of it this seems like a healthy hCG level. Good luck! Geoff Sher
Hormones & Ovulation Jun 19, 2024

infertility questions

Hi Dr. Sher, First off thank you for what you do & all of the valued information you provide people. Good information is hard to find on infertility. Here is my scenario: I am currently 39 y/o Female and my… — Holly B.

Dr. Geoffrey Sher answered

Hi Holy, Thank you for that detailed letter. I really would need to talk to you after receiving all relevant information. It does sound as if a male factor might be involved but I cannot vouch for this without more detail. It is possible (in spite of US…
Uterine & Endometrial Health Jun 19, 2024

Progesterone type

Is sub cutaneous progesterone as effective as intra muscular? Can there be a case of too much progesterone If progesterone gel, oral and sub cutaneous forms are administered together for luteal support? — Sreevidhya V.

Dr. Geoffrey Sher answered

Here is the Luteal Phase support I advocate. Luteal support: commences on day-1 , 6 days prior to the FET, with intramuscular progesterone in oil (PIO) at an initial dose of 75-100 mg (-Day 1). Daily administration- is continued until late in the evening of Day 5 (…
Embryos & Genetic Testing Jun 19, 2024

Gender Selection Options

Hello, What options are available that allow for gender selection? Thanks! Michelle B — Michelle B.

Dr. Geoffrey Sher answered

Couples have for centuries sought to influence the gender of their offspring. More than seven centuries ago the ancient Chinese developed a birth calendar said to be able to predict gender on the basis of when conception occurred. Later, the ancient Greeks suggested that by lying on her…
Uterine & Endometrial Health Jun 19, 2024

Vaginal viagra suppositories

Hi there I am from the UK and have been prescribed vaginal viagra suppositories but finding it impossible to find a pharmacy that can obtain it or make it up. Could you advise how the suppositories are made? Presumably they… — Helena G.

Dr. Geoffrey Sher answered

I really do not know how you could get access in the UK. I suggest you contact MD-RX Pharmacy in Encino, CA . They might be able to advise you.. Good Luck! Geoff Sher Ask for Robert Makhane and mention my name when you talk with him..
Cost & Insurance Jun 19, 2024

IVF cost

Hello Doctor I have listened to you on Egg Whisper and would like to come for IVF treatment from Tanzania. I am 48 years and would like to use my own eggs. My last eggs retrieval at 47 years we… — Esnath C.

Dr. Geoffrey Sher answered

Before making a final decision on how tom proceed, I suggest we talk. Let me tell you from the get go that doing IVF with own eggs at your age is not a wise option. Success rates are dismal....But let us have a dialogue about this. Geoff Sher…
Embryos & Genetic Testing Jun 17, 2024

Frozen embryo transfer add on

Hello Dr. Sher, Hope you are doing well.. 1. What is your view about hcg booster shots between ovulation induction and transfer for modified natural transfer? Does it have positive effect on endometrium before transfer? If yes what will be… — Sreevidhya V.

Dr. Geoffrey Sher answered

What is your view about hcg booster shots between ovulation induction and transfer for modified natural transfer? Does it have positive effect on endometrium before transfer? If yes what will be the ideal protocol and dose for hcg booster? A: I do not advocate this! 2. What is…

Ask Our Doctors

Supporting Your Journey

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

980 answers

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