Ask Our Doctors
I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.
– Geoffrey Sher, MD
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Hi, we are doing an ivf cycle in canada and plan to continue that here. However, we would like to get consultation from Dr. Sher to review our file, details, previous tries and provide recommendations remotely. We might be wrong but think the current clinic we are in and the previous one had limited resources or expertise.
we would like to book a consultation and hopefully you can help us with your expert opinion
I scored 1.8 on the Receptiva test, and had a laparoscopy two weeks ago that revealed pelvic and bowel adhesions, and a blocked tube (all likely caused by a past silent infection – not from endo?). They also found less than 1 cm of endometriosis on my left pelvic wall. All adhesions and endo were excised and the tube was removed, as well as a 9mm polyp in my uterus. My RE is saying that doing one month of Lupron will give me the best possible chance for my first upcoming FET to suppress any endo potentially missed or unseen. I’m wondering, would a month Lupron really make a difference when there was so little endo found? If it truly will increase my success rate for transferring, I’m open to trying it. But lupron seems to come with potential high risks so I don’t want to take it without likely impact for success!
I also saw your posts about blood testing for IID, including the APA and NKa. Is this something you advise testing prior to any FETs? And is that something our RE would be able to order, and how would we go about using one of the 3 reputable labs? (I live in AZ!)
Thank you in advance. I greatly appreciate you sharing your wisdom.
I recently moved to Las Vegas after being in Japan for 2 years. I had an embryo transfer on the 15th of July but its looking to be a blighted ovum. I have a confirmatory ultrasound scheduled for Monday with my primary OB provider.
I’m a little lost on how to move forward. I have 3 embryos still in Japan with no stateside clinic and no stateside provider who can perform FET. I had a successful FET last year and wanted to continue growing my family. But my job has strict limitations on where I can go and how long I can be gone for. Do you have any suggestions on how I can proceed forward?
As a follow up to my last question. Could you still do an FET if the lining thickens to a good size although the follicle is slow to develop/lack of ovulation. My lining is close to 7 mm despite having a small 10 mm follicle. Could I not transfer and supplement with progesterone since a thick lining is the most important?
Hi Dr. Sher,
I had a dating ultrasound last week on Tuesday and was measuring 5 w and 5 d and they did an hcg test with and my levels were 52819 H. Yesterday I had another ultrasound and measuring 6w and 2D with an hcg level of 55810 H. We saw a heart rate of 96 bpm. Should I be concerned of this pregnancy.
I am almost 40 and just did an egg retrieval on may. I have 5 euploids and 1 LLM. I also have pcos. I was hoping to do a modified natural cycle this month using 5mgs of letrozole. I have always responded well to letrozole on the past when I was doing timed intercourse. I’ve done 7 cycles in total using letrozole and ovidrel.
On day 10 all my follicles were between 7-9 mms and my lining was 6. Today, day 13 my biggest follicle is 10 mm and my lining is 6.7. I’m so discouraged. I have to go back in 3 days for a recheck. My cycles are fairly regular, between 30-32 days.
Do you think this mean I’m out this month? Could I try letrozole at 7.5 mgs next month? I’m trying to stay away from taking estrace. I also don’t want to take clomid due to ovarian cancer risks.
I am currently 18 weeks pregnant following a fresh IVF transfer.
Would you advise that I stay on lovenox 0.4 during the whole pregnancy since I have the following genetic mutations?
– homogenous MTHFR 677CT
– heterozygous PAI 4G/5G
Also would it be advised that I take a low dose of progesterone throughout the pregnancy?
I do not have recurrent miscarriage but it took me 6 years in total to get a continuing pregnancy. My last pregnancy ended in a miscarriage at 9 weeks (following IVF but I wasn’t on any medication), 3.5 years ago. After that we had a lot of failed transfers before our successful transfer.
Hi Dr Sher, apologies to bother you again, your insights are so helpful and I’m worried this IVF round isn’t going to work! It’s a Euploid embryo being transferred that I don’t want to wast. We’re doing a modified natural cycle (as mentioned in my previous message).. and instead of triggering the day dominant follicle was 20mm.. we waited a day, so a day later on day 11.. so not before the LH surge, but close to it, if not on it.. We’ll be transferring in 7 days time (from trigger) and will be starting progesterone support in 24 hours time.. I’m worried the timing will be out because we triggered one day late.. would you recommend we cancel? Many thanks in advance! Best wishes, Cassidy
I went in for a scan today in anticipation of doing a modified natural cycle, it’s day 10 – LH levels are rising -I’ve not reached ovulation yet, LH normally surges on day 14 for me. The lining was trilaminar and 9.5mm in thickness and lead follicle was 23mm. The nurse said trigger tonight and come in next Monday for transfer. I asked whether there was any benefit in delaying trigger, letting my lining grow a bit more naturally before we trigger (historically it has grown a bit each day). She said she was happy to postpone the transfer date by a couple of days.. so that’s what we’re doing.. The plan is to trigger on day 12 (instead of day 10), assuming I’ve not got my surge before then, and start progesterone that day and transfer 7 days after trigger…Does that sound like a sensible plan to you – does it hurt to let the lining grow a bit thicker before we trigger? Many thanks for your help in advance! Best wishes, Cassidy.
I am 42, 2.15 AMH, did the first cycle with Decapeptyl only and got all empty follicles. Then did three more cycles with dual trigger and got no euploids. Should I try an Ovidrel only trigger? 500 or 250? (I am low BMI) Thanks a lot in advance for any guidance.
To whom it may be concerned,
I am Dr. Amy Huang’s patient. After more than one year of getting pregnancy naturally, we decided to move forward with other options.
I got referral from Dr. Huang and would like to make an appointment.
Kindly let me know what information you need from me.
My name is Claire…I’ve had 3 pregnancy losses ..one was at 6weeks and the rest were chemical pregnancies they exited even before I noticed I was pregnant..my gyna did thyroid.. diabetes and immune disorder test with my blood and found nothing …but my BMI is 35….am confused and traumatized…what kind of advise would u give…what should I do next I really wanna conceive but this time successfully..but am full of fear..what could be the cause of my miscarriages?…can I try and succeed next time…?..what’s your prediction what could be the cause?….please advise on how or what I can do to carry successfully to term next time I try
Hi, I came across your podcast about implantation issues.
I went thru infertility issues for 4 years (Ivf wasn’t covered) 19iuis- I had a miscarriage in the 2nd trimester- 3 chemical pregnancies and 2 miscarriages ending before 9 weeks we did Ivf- my daughter was the only normal embryo – had one transfer and got pregnant and had a healthy pregnancy.
I went back for retrieval and got 19 normal embryos – first round back had an ectopic 2nd round had a chemical and I’m on my 3rd round now- my linning always takes forever to thicken but finally after a month gets to 10/11- this last transfer my doctor has put me under to get to my uterus because the other 2 times were difficult to reach my uterus due to being tilted and scar tissue from C-section. I’m on day 7 post transfer and have a super light positve which I’m guessing will result in another chemical – to say I’m heart broken is an understantment- all 3 of these transfers have been boys- is it possible the boy embryos could be an issue? Could my uterus be the issue? I’m not sure my question- what should I ask my doctor at this point? I’m 38 will be 39 in feb- I have another boy left and 13 girls – help me 🙁