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Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

  • Dear Patients,

    I created this forum to welcome any questions you have on the topic of infertility, IVF, conception, testing, evaluation, or any related topics. I do my best to answer all questions in less than 24 hours. I know your question is important and, in many cases, I will answer within just a few hours. Thank you for taking the time to trust me with your concern.

    – Geoffrey Sher, MD

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Search 1,018 questions patients have already asked, or narrow them by topic.

Latest answers

Page 1 of 68

  1. IVF Failure & Pregnancy Loss

    Recurrent Implantation Failure

    Hello, I have PMOS and stage 1 endometriosis, which was recently excised. I have done 7 embryo transfers which resulted in 4 early miscarriages and 3 failures. The clinic I am currently at will not explore immunilogic factors or treatments.… — Julie D.

    Dr. Geoffrey Sher answered

    It is amazing to me that your clinic is so closed minded. Here is an article I wrote on implantation dysfunction. If you would like to have an online discussion with me, please email Patti at concierge@sherIVF.com and she will set it up. Implantation Dysfunction: An Under-recognized Cause…

  2. Egg Health & Ovarian Reserve

    Low amh

    How can i increase my egg quality — Ade B.

    Dr. Geoffrey Sher answered

    We need to talk. Call Patti at 702-566-2691 and set up an online consultation with me. GS The Most Important Decision in IVF: Choosing the Right Ovarian Stimulation Protocol: Why Individualized Ovarian Stimulation May Be the Single Most Important Modifiable Factor Determining IVF Success by Geoffrey Sher MD/Drew…

  3. Egg Health & Ovarian Reserve

    IVF & DOR

    Hello Dr. Sher ! My name is Christina and I’ve been watching many of your videos. I believe your expertise and view on DOR could help me in my journey of IVF cycles :) below is my history in brief… — Christina V.

    Dr. Geoffrey Sher answered

    Age is on your side but your ovarian reserve is a problem. You need a very strategic protocol. WE should talk! I suggest that you email my assistant, Patti converse (concierge@sherivf.com) and she will set you up with on online consultation so we can interact one-on-one. In the…

  4. Infertility Basics

    Sperm Analysis Summary & Inquiries – Trying to Conceive for 1 Year

    ​I would like to share the summary of my husband's recent sperm analysis (Spermiogram) as we have been trying to conceive for one year without success. Here are the key findings: ​Volume & Concentration: Normal (Volume: 2.1 ml, Concentration: 50… — Fares D.

    Dr. Geoffrey Sher answered

    I do not believe this is likely to be an intractable sperm issue. WE should talk! I suggest that you email my assistant, Patti converse (concierge@sherivf.com) and she will set you up with on online consultation so we can interact one-on-one. In the interim...see below! Geoff Sher

  5. Egg Health & Ovarian Reserve

    What protocol is best for me? 42, amh 4.34, afc 17-25,

    Hi Dr Sher, please guide me urgently. Im currently in a cycle im thinking of cancelling. Started a Synarel (lupron) prime three weeks then stopped and started stims next day 150 menopur, 75 gonalf and hgh. My follicles were 17… — Kylie M.

    Dr. Geoffrey Sher answered

    WE should talk! I suggest that you email my assistant, Patti converse (concierge@sherivf.com) and she will set you up with on online consultation so we can interact one-on-one. In the interim...see below! Geoff Sher The Most Important Decision in IVF: Choosing the Right Ovarian Stimulation Protocol: Why Individualized…

  6. Embryos & Genetic Testing

    Inflammation

    Riddle me this: 2 missed miscarriages, 2 chemical pregnancies: asthma returned during pregnancy, allergies, wheezing with alcohol, RH - blood type, hx endometritis, often lower WBC (but within a "normal range"), sister has MTHFR gene mutation (ive not been tested).… — Rebecca A.

    Dr. Geoffrey Sher answered

    WE should talk! I suggest that you email my assistant, Patti converse (concierge@sherivf.com) and she will set you up with on online consultation so we can interact one-on-one. In the interim...see below! Geoff Sher Understanding Recurrent Pregnancy Loss (RPL): Looking Beyond “Bad Luck” Recurrent Pregnancy Loss (RPL), often…

  7. Egg Health & Ovarian Reserve

    35F with DOR post ovarian fibroma surgery

    I am 35 years old and underwent laparoscopic removal of a benign ovarian fibroma. I have DOR with last AMH < 3 pmol/L. My cycles have gradually shortened from 28–30 to 23–27 days, although I appear to ovulate regularly. We… — A. S.

    Dr. Geoffrey Sher answered

    I would personally NOT recommend either a natural cycle or a mini-stim cycle. You have very severely diminished ovarian reserve and it might not be possible to elicit an adequate response. We need to talk! I suggest that you email my assistant, Patti converse (concierge@sherivf.com) and she will…

  8. Egg Health & Ovarian Reserve

    Age 40, 0 euploid of 3 on first retrieval. What would you change for cycle 2?

    I'm 40 (born June 1986) and just finished my first IVF retrieval at a Boston clinic. Goal is two children, so I'm banking embryos. What would you change to improve egg quality and euploid yield before cycle 2? Reserve and… — Annmarie E.

    Dr. Geoffrey Sher answered

    We would need to talk! However, I would probably use an agonist/Antagonist conversion protocol . I suggest you set up an online cosultation with me to discuss! Email Patti at concierge@sherivf.com and she will set this up. GS The Most Important Decision in IVF: Choosing the Right Ovarian…

  9. Embryos & Genetic Testing

    FET with Viagra help

    Dr. Sher, I have been following you for quite some time and have found your research with IVF extremely helpful. I have completed 2 IVF cycles which have resulted in two precious embryos. I have attempted two FET attempts but… — Amanda K.

    Dr. Geoffrey Sher answered

    It would be my pleasure to interact with you. However, you should please contact my office Manager, Patti Converse and have her send you a brief questionnaire to complete, upon which she will set you up with an online consultation and we can discuss your issues in detail..…

  10. Embryos & Genetic Testing

    I’m 41. I did one IVF retrieval cycle, which produced two PGT-A–tested euploid 5AA blastocysts, one female and one male. I previously had a left laparoscopic salpingectomy, and my hysteroscopy was normal. My first medicated frozen embryo transfer was on July 22, 2026. The (XX) embryo survived thawing completely, re-expanded, and was hatching at transfer. I used estradiol, daily progesterone in oil, low-dose aspirin, NP Thyroid, and prenatal vitamins. My first beta-hCG was 9.5 mIU/mL at 9 days post-transfer, but it decreased to 1.5 mIU/mL four days later, confirming a biochemical pregnancy. My second (XY) medicated transfer was performed on September 16, 2026, after Lupron suppression and apparently adequate endometrial preparation. The protocol included estradiol, progesterone in oil, heparin twice daily, low-dose aspirin, NP Thyroid, prenatal vitamins, and azithromycin. Despite transferring the remaining euploid 5AA embryo, the beta-hCG test was negative, indicating implantation failure. In summary, I have experienced one biochemical pregnancy and one failed implantation following the transfer of two euploid 5AA embryos both Lining 12, with no embryos remaining.

    Is there any treatment that could help me become pregnant and carry a baby myself, rather than using a surrogate? — Mariana R.

    Dr. Geoffrey Sher answered

    Possibly ,...BUT..It depends on your situation and clinical circumstances! Geoff Sher

  11. Clinic & Practice

    New patients: importing frozen oocytes from Spain, ICSI with frozen sperm, and double embryo transfer

    Hello Sher Team, We live in New York City and are considering importing our frozen oocytes and embryos from Instituto Bernabeu (Alicante, Spain) to your clinic, to fertilize them with Julian's frozen sperm. Before booking a consultation, we would be… — Julian W.

    Dr. Drew Tortoriello answered

    It would be my pleasure to interact with you. However, you should please contact my office Manager, Patti Converse and have her send you a brief questionnaire to complete, upon which she will set you up with an online consultation and we can discuss your issues in detail..…

  12. Clinic & Practice

    Consultation Request – DOR and Difficult Response to IVF Stimulation

    Dear Dr. Sher, I would like to arrange a consultation regarding my IVF history and response to stimulation. I have diminished ovarian reserve (DOR) with a very low AFC and have had several disappointing cycles with inconsistent responses. My current… — Daniela K.

    Dr. Geoffrey Sher answered

    It would be my pleasure to interact with you. However, you should please contact my office Manager, Patti Converse and have her send you a brief questionnaire to complete, upon which she will set you up with an online consultation and we can discuss your issues in detail..…

  13. Third-Party Reproduction

    Hmmmm

    Am 55 I would like to start my journey to become a mother — Doris A.

    Dr. Geoffrey Sher answered

    You need IVF with egg donation. WE would need to talk. Call Patti at 702-533-2691 or email her at conscierge@sherivf.com and set up an online consultation with me.

  14. Uterine & Endometrial Health

    Thin uterine lining

    Here’s a polished version with that additional context incorporated: • Seeking a second opinion regarding persistent thin endometrial lining and whether there are any additional diagnostic or treatment options that may be worth considering. • I experienced a miscarriage last… — Lauren M.

    Dr. Geoffrey Sher answered

    WE would need to talk. Call Patti at 702-533-2691 or email her at conscierge@sherivf.com and set up an online consultation with me. ANATOMICAL UTERINE CAUSES OF EMBRYO IMPLANTATION DYSFUNCTION Why Good Embryos Sometimes Fail to Implant—and How Identifying Hidden Uterine Factors Can Transform IVF Failure into Success SHER…

  15. Clinic & Practice

    Transfer embryo

    I am 47 years old, Do you think transfer embryo is possible for me — NadiaJnBaptiste M.

    Dr. Geoffrey Sher answered

    You need IVF with donor egg! Geoff Sher (call us at 702-533-2691) THE GIFT OF POSSIBILITY: FRESH DONOR EGGS, EGG BANKING, AND THE NEW ERA OF FAMILY BUILDING A Revolution in Reproductive Medicine Few developments in reproductive medicine have changed the lives of infertile women and couples as…

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