Blog - Sher Fertility Solutions

Violet™ Artificial Intelligence (AI)-based Software: A Break-through in the Field of Egg Banking which Reliably Predicts Reproductive Potential by Scoring “Egg Competency”

By Dr. Geoffrey Sher

In order for a human embryo to develop into a viable, healthy
pregnancy it needs to be “competent” (capable, upon being
transferred to the uterus, of propagating a viable pregnancy).
Currently, the most reliable determinant of such embryo
“competence” is the measurement of the number of chromosomes in
the embryo’s cells (i.e., its karyotype). An embryo whose cells have
all 46 chromosomes intact, is seen as a requirement and therefore
deemed to be one that is most likel…

Violet™ Artificial Intelligence (AI)-based Software: A Break-through in the Field of Egg Banking which Reliably Predicts Reproductive Potential by Scoring “Egg Competency” Read More »

Total Absence of Sperm in the Ejaculate due to Complete Obstruction of the Vas deferens: Congenital or acquired.

By Dr. Geoffrey Sher

Following male orgasm, sperm are ejaculated after traveling rapidly in
sequence through the vas deferens duct, the prostate gland, and the
urethra. The vas deferens must be patent to allow the passage of sperm
in the ejaculate.

CAUSES OF TOTAL OBSTRUCTION OF THE VAS DEFERENS:

* _Primary occlusion: Congenital (Bilateral) Absence of the Vas
Deferens (CBAVD): _In some cases men are born with occlusion of
the vas deferens, obstructing the…

Total Absence of Sperm in the Ejaculate due to Complete Obstruction of the Vas deferens: Congenital or acquired. Read More »

Egg Banking-Fertility Preservation

By Dr. Geoffrey Sher

THE BOTTOM LINE IS THAT BECAUSE OF THE TRAUMATIC EFFECT OF FREEZING ON
EGG VIABILITY AND “COMPETENCY” THE STATISTICAL CHANCE OF EACH
FROZEN/ THAWED EGG ULTIMATELY RESULTING IN A BABY IS ONLY AT BEST
6-8%. SO, WHILE SUCCESS RATES FOLLOWING THE TRANSFER OF EMBRYOS
DERIVED FROM FROZEN EGGS HAVE INDEED IMPROVED SUBSTANTIALLY OVER THE
LAST 5-10 YEARS, THEY REMAIN SIGNIFICANTLY LOWER THAN WHEN EMBRYOS
DERIVED THROUGH FERTILIZATION OF FRESH (NOT FROZEN) EGGS, ARE
TRANSFERRED. …

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Recurrent Pregnancy Loss (RPL)

By Dr. Geoffrey Sher

The bottom line is that because of the traumatic effect of freezing on
egg viability and “competency” the statistical chance of each
frozen/ thawed egg ultimately resulting in a baby is only at best
6-8%. So, while success rates following the transfer of embryos
derived from frozen eggs have indeed improved substantially over the
last 5-10 years, they remain significantly lower than when embryos
derived through fertilization of fresh (not frozen) eggs, are
transferre…

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Prolactin (PRL)

By Dr. Geoffrey Sher

Prolactin (PRL) is a protein hormone (closely related to human growth
hormone
[/blog/human-growth-hormone-administration-in-ivf-does-it-enhance-eggembryo-quality-and-outcome/])
that is secreted by specialized cells in the anterior part of the
pituitary gland. In addition, the hormone is also produced and
secreted by a broad range of other cells in the body, most prominently
variou…

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EZ-IVF

By Dr. Geoffrey Sher

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EZ-IVF Read More »

EZ-IVF: AN IMPROVED , LOW-COST, LOW-STIMULATION, SAFE & SUCCESSFUL ALTERNATIVE T0 MINI-IVF AND NATURAL CYCLE-IVF

By Dr. Geoffrey Sher

Geoffrey Sher MD & Drew Tortoriello MD
Mini-IVF is a procedure that involves ovarian stimulation with oral
fertility drugs such as clomiphene or letrozole to promote the
development of follicles, for egg extraction. This is on the pretext
that Mini-IVF, involves the administration of oral low-dosage
medication, cuts down on cost, reduces the need for intensive
monitoring and is highly successful. Natural-cycle (NC)- IVF is an
extension of the same concept….

EZ-IVF: AN IMPROVED , LOW-COST, LOW-STIMULATION, SAFE & SUCCESSFUL ALTERNATIVE T0 MINI-IVF AND NATURAL CYCLE-IVF Read More »

Hormonal Treatment of Male Infertility

By Dr. Geoffrey Sher

There exists in the man a cyclical production of spermatozoa where
the duration of spermatogenesis from takes approximately 90 days. It
follows that, any treatment aimed at enhancing sperm production
requires approximately a period of 3 months. Since the enhancement of
testicular function must of necessity be mediated through FSH and LH
it follows that in order to assess response to testicular stimulatory
drugs it is necessary to get a baseline FSH, LH and testosterone as
well as a semen…

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Reno Gazette Journal

Cyclical Estrogen Therapy Prior to Embryo Transfer, in Post-Menopausal Women and those with Prolonged Hypothalamic Amenorrhea, Can Reduce the Chance of Failed IVF and Miscarriage

By Dr. Geoffrey Sher

An absence of menstruation (amenorrhea) in reproductive age women is
usually due to an absence of ovulation (anovulation). If this becomes
prolonged, then these women are at risk for the ill effects associated
from chronically low estrogen levels (hypoestrogenemia).
Specifically, the women at risk for this would be those experiencing
premature ovarian failure (early menopause) or hypothalamic
amenorrhea. Whatever the cause, hypoestrogenemia will eventually lead
to a shrinkin…

Cyclical Estrogen Therapy Prior to Embryo Transfer, in Post-Menopausal Women and those with Prolonged Hypothalamic Amenorrhea, Can Reduce the Chance of Failed IVF and Miscarriage Read More »

The Sacramento Bee

The Role of IVF in the Management of Infertility Caused by Pelvic Inflammation

By Dr. Geoffrey Sher

Pelvic Inflammatory Disease (PID) refers to inflammation of pelvic
structures including the uterus, fallopian tubes
[/blog/role-ivf-cases-tubal-damage/], ovaries, bowel, and the smooth
membrane that lines the surface of the pelvic cavity (the peritoneum).
PID
[/blog/pelvic-inflammatory-disease-pid-tubal-damage-hydrosalpinx-preparing-ivf/]
follows inf…

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