IVF: Should Treatment Cycles be Uninterrupted or be Conducted in Pre-scheduled Batches?

The conventional way of conducting IVF treatment is to provide
patients with opportunity to undergo treatment any time they are ready
to do so. But such delivery of services in fact often falls short of
affording access to the most efficient and best quality of treatment
because it fails to allow much needed opportunities for clinical and
laboratory staff to take much needed breaks in order to implement
optimal quality control and to recover from the pressure resulting
from uninterrupted…

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Reflecting upon the Use and Misuse of Intrauterine Insemination (IUI): Time for a Serious Reality Check

It is hard for me to believe that more than three decades have flown
by since I first introduced intrauterine insemination into the
clinical arena (Journal of Fertility & Sterility, April, 1984). At
that time and for more than 2 decades thereafter, I held the strong
belief that IUI would provide a less expensive, safe and equally
successful alternative to  IVF in cases where the woman had at least
one patent Fallopian tube… How wrong I was! In my defense however,
let me say that in th…

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GnRH Antagonists (Ganirelix/Cetrotide/Orgalutron) in IVF Ovarian Stimulation Protocols

CONVENTIONAL GNRH ANTAGONIST (GNRHA) PROTOCOLS: GnRH antagonists (e.g.
Ganirelix, Cetrotide, and Orgalutron) are currently used with many
controlled ovarian stimulation (COS)
[/blog/controlled-ovarian-stimulation-cos-for-ivf-selecting-the-ideal-protocol/]
protocols. The conventional approach is to administer 250mcg
antagonist, daily starting from the 6th-8th day afte…

GnRH Antagonists (Ganirelix/Cetrotide/Orgalutron) in IVF Ovarian Stimulation Protocols Read More »

Testing for Immunologic Implantation Dysfunction (IID): Who Should be Tested, Where Should Testing be Done and How should results be interpreted?

Unless tests for immunologic implantation dysfunction (IID) i
[https://blog.drgeoffreysherivf.com/endometriosis-immunologic-implantation-dysfunction-iid-ivf/]mmunologic
implantation dysfunction [/blog/endometriosis-and-infertility-sfs/]are
performed correctly and conducted by a one of the few reliable
reproductive immunology reference laboratory in the United States,
treatment will likely be unsuccessful. . In this regard…

Testing for Immunologic Implantation Dysfunction (IID): Who Should be Tested, Where Should Testing be Done and How should results be interpreted? Read More »

Ureaplasma and Infertility: How Can It Affect IUI/IVF Outcome?

Ureaplasma urealyticum is a bacterium that belongs to the mycoplasma
family. It can be detected in the reproductive tract of as many as 40%
of individuals (male and female). Ureaplasma probably does not prevent
normal conception in the majority of cases, because by and large, the
uterine cavity remains  free of such pathogenic bacteria even in
women whose cervical mucous cultures positive for the organism.
However, when present in the woman’s cervical secretions, the
organism can be u…

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Multiple Pregnancies Carry Serious Risks: How Many Embryos Should we Transfer at One Time?

All multiple pregnancies pose a risk to both mother and offspring.
Pregnancy induced maternal complications such as miscarriage,
pre-eclampsia, antepartum and post-partum hemorrhage become
progressively more prevalent the higher the multiple gestation. For
the babies, it is an escalating risk of premature birth and
intrauterine growth retardation that places the offspring at risk.

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A Fresh Look at Ovarian Hyperstimulation Syndrome (OHSS)

Ovarian hyperstimulation syndrome (OHSS) is a life-endangering
condition that occurs following ovarian stimulation
[/blog/ovarian-stimulation-for-women-with-diminished-ovarian-reserve-dor-and-in-older-women-undergoing-ivf/]
for the treatment of infertility. It occurs due to overstimulation of
the ovaries with the development of numerous follicles in susceptible
women. S…

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IVF: Selecting the Best Quality Embryos to Transfer 2

The numerical chromosomal configuration of a cell is referred to as
its karyotype or ploidy. A cell with an irregular chromosome number is
referred to as aneuploid while one with a normal karyotype, as
euploid. It is predominantly (but not exclusively) the chromosomal
configuration of the embryo that determines its subsequent ability,
upon reaching a receptive uterine environment, to propagate a normal
pregnancy, also referred to as its “competence.” A “euploid”
(compet…

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Male Infertility

Male factor problems as a contributing cause of infertility are very
common. Male infertility is reported as a factor in 30-50% of
infertility cases. In fact, many fertility specialists will recommend
a semen analysis as one of the very first tests that should be done.
It is relatively simple, inexpensive and yields much information. The
two main causes of male factor infertility can be divided into either
problems in manufacturing sperm or problems in getting sperm outside
of the body (…

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The IVF Journey: The importance of “Planning the Trip” Before “Taking the Ride”

The objective with In Vitro Fertilization is to consistently transfer
competent embryos into a receptive uterine environment. This requires
a very individualized and meticulous approach to evaluating and
addressing those factors that can influence IVF outcome
[/blog/fundamental-requirements-achieving-optimal-ivf-success/]: All
patients/couples should learn what they can reasonably expect before
committ…

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