Blog - Sher Fertility Solutions

Deciding between Egg and Embryo Banking for Fertility preservation (FP)

By Dr. Geoffrey Sher

Women should not delay trying to have a baby
[/blog/new-advancing-age-diminished-ovarian-reserve-dor-affect-eggembryo-competency-problem-addressed/],
thinking that as long as they are ovulating regularly the biological
clock can simply be put on hold or that they can simply to freeze
their eggs and then later decide if/when to thaw them for use. T…

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How can stress affect IVF?

By Dr. Geoffrey Sher

There is little doubt that stress and emotional lability plays a role
in the normal physiological/hormonal regulation of the menstrual
cycle. After all, Eskimos often stop ovulating and menstruating during
long dark winters, young women confronted by a major emotional trauma
such as a broken love affair can develop

How can stress affect IVF? Read More »

IVF: Immature and Post-mature Egg Cells: What does this mean and how can it be prevented?

By Dr. Geoffrey Sher

One commonly hears patients undergoing IVF report that they had too
many “immature eggs”, and inferring that had more time been allotted
to ovarian stimulation and the administration of the “trigger shot
been delayed by a day or more, this might not have happened. Nothing
could be farther from the truth. In fact, the duration of ovarian
stimulation is rarely the cause of egg “immaturity”. More often than
not can be attributable to the use of a sub-opti…

IVF: Immature and Post-mature Egg Cells: What does this mean and how can it be prevented? Read More »

How Old is Too Old to Do IVF Using Your Own Eggs?

By Dr. Geoffrey Sher

There is little doubt that age is a very important determinant of IVF
outcome. This is mainly because a woman’s eggs undergo
deterioration in quality as her age advances to and beyond her mid
30’s. Remember, eggs have been in the woman’s ovaries ever since
she was incubating in her mother’s uterus. Thus, after a certain
period of time….when she reaches her mid 30’s, a wear and tear
effect increases the likelihood of chromosomal abnormalities that
become unmasked with th…

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(NEW) IVF: Approach to Selecting the Best Embryos for Transfer to the Uterus.?

By Dr. Geoffrey Sher

The numerical chromosomal configuration of a cell is referred to as
its karyotype or ploidy. A cell with an irregular chromosome number is
referred to as aneuploid while one with a normal karyotype, as
euploid. It is predominantly (but not exclusively) the ploidy of the
embryo that determines its subsequent ability, upon reaching a
receptive uterine environment, to propagate a normal pregnancy, also
referred to as its “competence.” A “euploid (“competent”)
embryo tr…

(NEW) IVF: Approach to Selecting the Best Embryos for Transfer to the Uterus.? Read More »

Gestational Surrogacy for a Case of Rokitansky Syndrome: 2 Frozen Embryo Transfers Yields 3 Babies.

By Dr. Geoffrey Sher

[CASE REPORT]_THIS IS A RE-POST FOR PURPOSES OF FOLLOW-UP (SEE
POST-SCRIPT AT THE END)._BACKGROUND: Mary, 30 years of age and married
to a fertile male partner
[/blog/diagnosing-treating-male-factor-infertility/], presented to me
about four years ago with primary

Gestational Surrogacy for a Case of Rokitansky Syndrome: 2 Frozen Embryo Transfers Yields 3 Babies. Read More »

IVF: After How Many Tries Should I Give Up?

By Dr. Geoffrey Sher

Because of the emotional, physical, and financial toll
[/blog/cost-of-ivf-treatment/] exacted by IVF, it is preferable that
no one undertake a one‑shot attempt. If a couple can only afford one
treatment cycle, IVF is probably not the right course of action.
After all, with conventional IVF there is only about one chance in
three that it will result in a live birth ‑and a tremendous letdown
if it fails. It is thus unreasonable to undergo IVF…

IVF: After How Many Tries Should I Give Up? Read More »

IVF & Polycystic Ovarian Syndrome (PCOS): Reducing the Risk of Severe Ovarian Hyperstimulation Syndrome (OHSS), Improving Egg Quality and Optimizing Outcome

By Dr. Geoffrey Sher

Polycystic ovary syndrome (PCOS)
[/blog/new-ivf-outcome-patients-polycystic-ovarian-syndrome-pcos/] is
a common hormonal system disorder among women affecting between 5% and
10% of women of reproductive age worldwide. Women with PCOS may have
enlarged ovaries that contain multiple small collections of fluid
(subcapsular microcysts) that are arranged like a “string of
pearls” immediately below the ovarian su…

IVF & Polycystic Ovarian Syndrome (PCOS): Reducing the Risk of Severe Ovarian Hyperstimulation Syndrome (OHSS), Improving Egg Quality and Optimizing Outcome Read More »

Deciding Between Intrauterine Insemination (IUI) and In Vitro Fertilization (IVF)

By Dr. Geoffrey Sher

Many infertile patients, are erroneously advised by their physicians
to first try IUI
[/blog/reflecting-upon-use-misuse-intrauterine-insemination-iui-time-serious-reality-check/]
several times before resorting to IVF. Additionally many misguided
insurance providers often, purely for economic
[/blog/ivf-the-economic-realities/] reasons, req…

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How Does Advancing Age and Diminished Ovarian Reserve (DOR) Affect Egg/Embryo “Competency” and How Should the Problem be Addressed.

By Dr. Geoffrey Sher

It is primarily the egg (rather than the sperm) that determines the
chromosomal integrity (karyotype) of the embryo, the most important
determinant of egg/embryo competency
[/blog/ivf-factors-affecting-egg-embryo-competency-during-controlled-ovarian-stimulation-cos/].
A “competent” egg is therefore one that has a normal karyotype and
has the best potential to pro…

How Does Advancing Age and Diminished Ovarian Reserve (DOR) Affect Egg/Embryo “Competency” and How Should the Problem be Addressed. Read More »