Progesterone-Estrogen Hormonal Supplementation in IVF: How Does it Work and What is its Value?
Ovulation occurs within 38-42 hours of initiation of the spontaneous luteinizing hormone (LH) surge (which can be detected in the blood or urine prior…
Sher Fertility Solutions
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Ten years of writing on IVF, fertility and reproductive medicine from Sher Fertility Solutions. Ten years of writing on IVF and fertility.
Antisperm Antibodies, Infertility, and the Role of IVF with Intracytoplasmic Sperm Injection
Antisperm antibodies (ASA) are immunoglobulins that attach to sperm. They are most commonly encountered in semen, blood, cervical mucous and follicular fluid. Not all…
“Triggering” Egg Maturation in IVF: Comparing urine-derived hCG, Recombinant DNA-hCG and GnRH-agonist
Ideal egg development sets the scene for optimal egg maturation that occurs 36-42h prior to ovulation or egg retrieval. Without prior optimal egg development…
Ectopic (Tubal) Pregnancy and IVF
Approximately 1 out of every 100 embryos will implant and grow outside of the uterine cavity, almost always in a fallopian tube. This is…
The Fundamental Requirements For Achieving Optimal IVF Success
Given the considerable emotional, physical and financial investment associated with IVF treatment [/blog/confronting-the-real-cost-of-ivf-treatment/], it is essential that factors known to affect success be identified…
“Functional” Ovarian Cysts and IVF
An ovarian cyst [http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024724] is any collection of fluid, surrounded by a very thin wall, within an ovary [http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0022599]. An
Varicocele and Male Infertility
What is a varicocele? The testicles are housed in the scrotum, a skin-covered sac that houses the two testicles as well as blood vessels…
Viagra as a Treatment to Thicken Uterine Lining
About seventeen years ago, after reporting on the benefit of vaginal Sildenafil (Viagra) for women who had implantation dysfunction due to thin endometrial linings,…
Intralipid and IVIG Therapy in the Treatment of Immunologic Implantation Dysfunction
There is an ever growing realization, recognition, and acceptance of the fact that uterine immunologic dysfunction can lead to immunologic implantation dysfunction (IID) [/blog/diagnosing-and-treating-immunologic-implantation-dysfunction-iid/]…
Janet Jackson Delays Tour to Start Family: How Old is too Old for IVF?
More and more women are deciding, based upon personal preference and professional necessity, to postpone having a family to a later age. In fact,…
Pros and Cons of The Lupron (Leuprolide) Trigger Shot
Traditionally, IVF egg retrievals are timed for about 36 hours after a 10,000U hCG “trigger”. The hCG hormone thereupon remains in the system for…
How Does Bodyweight Affect Fertility and IVF Outcome?
The prevalence of obesity in Western societies is on the rise, which has a profound effect on the reproductive performance of women who are…
Premature Luteinization (“the premature LH surge): Why it Happens and how it can be Prevented
Premature luteinization ("premature LH surge") occurs when prior to the planned initiation of the hCG trigger, a progressive rise in LH, irreversibly compromises follicle…
Induction of Ovulation With Clomiphene Citrate: Mode of Action, Indications, Benefits, Limitations and Contraindications for its use
Clomiphene (Clomid, Serophene) is by far the most widely prescribed agent for the induction of human ovulation for women who do not ovulate, those…
Uterine Fibroids and Fertility: Causes & Treatment Options
Fibroids or leiomyomas are non-malignant muscle tumors that grow in the uterine wall. They can be found in about one out of every five…
Natural Killer Cell Activation (NKa) and Immunologic Implantation Dysfunction (IID) in IVF: The Controversy!
“Innovators are rarely received with joy, and established authorities launch into condemnation of newer truths; for at every crossroad to the future are a…
How Many Embryos Should be Transferred: A Critical Decision in IVF
The decision on how many embryos to transfer confronts most IVF physicians and their IVF patients. It is driven by a goal that both…
Frozen Embryo Transfer (FET): A Rational Approach to Hormonal Preparation and How new Methodology is Impacting IVF
Until about 15 years ago, we believed that the best and safest way to cryopreserve embryos was by using a slow freezing method. What…
Human Growth Hormone (Omnitrope) in IVF
The term “Biological Clock [/blog/the-biological-clock-and-how-it-should-influence-the-selection-and-design-of-ovarian-stimulation-protocols-for-ivf/]” is used to define the time line for a woman’s reproductive potential. It is affected primarily by two factors:…
Adenomyosis Related Infertility: A Therapeutic Challenge
Adenomyosis is a condition where endometrial glands develop outside the uterine lining (endometrium) [/blog/viagra-treatment-thicken-uterine-lining/], within the muscular wall of the uterus (myometrium). A definitive…