Dr. Sher,
I convinced my IVF doctor to let me use your agonist/antagonist conversion protocol with Zomacton (using Ganirelix to replace Lupron and keep using it until trigger date). My March cycle resulted in 4 eggs retrieved, 3 fertilized, unfortunately none to blast. However, when I used the same protocol again earlier this month (August-2024), there is only 1 GV graded egg retrieved. It did mature overnight but fail to fertilized. I did a PRP session in May to hope to boost my ovary reserve. From your experience, is the difference of AFC and egg retrieval outcome more likely to be attributed to potentially spoiled medication (Gonal-f pens were gifted by other patients w an almost-expiring date) or my overall slow reaction to BCP? I’ve noticed that in both cycles, it took about 8 days from stopping BCP to have menses onset. If I don’t use BCP and Lupron to start the protocol, would the conversion protocol still works for DOR patient like me?
My info:
46 yr old, AMH 0.34, FSH 2.6, LH 2.2 (all day 3 values)
highest stim dose: 300 IU gonal-f, 150 IU manepour daily
Thank you so much!