RIF

We have had 1 successful implantation which ended in a miscarriage at 8 weeks. 1 chemical pregnancy and 4 failed implantation – 3 of which were with euploid embryos. Husband has poor SA (varicocele) and I have been diagnosed with endometriosis. We’ve done PGT, EMMA & ALICE, ERA, laparoscopy. Husband has just done a tunnel assay and been informed he has elevated DNA fragmentation. All our IVF cycles are with ICSI. There’s a lot of contradictory info on DNA fragmentation – whether it affects implantation or not. Is it worth doing TESA? Is ICSI sufficient? What should we be doing differently?

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